An analysis of protocols and publications suggested that most discontinuations of clinical trials were not based on preplanned interim analyses or stopping rules

DISCO Study Grp, Mihaela Stegert, Benjamin Kasenda, Erik von Elm, Matthias Briel, K. A. Tikkinen

Research output: Contribution to journalReview ArticleScientificpeer-review

Original languageEnglish
JournalJournal of Clinical Epidemiology
Volume69
Pages (from-to)152-160
Number of pages9
ISSN0895-4356
DOIs
Publication statusPublished - Jan 2016
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • Randomized controlled trials
  • Protocol
  • Early termination of clinical trials
  • Data monitoring committees
  • Interim analysis
  • Stopping Rules
  • RANDOMIZED-TRIALS
  • 3141 Health care science
  • 3142 Public health care science, environmental and occupational health

Cite this