An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

Sanni E. Ruotsalainen; Juulia J. Partanen; Anna Cichonska; Jake Lin; Christian Benner; Ida Surakka; Mary Pat Reeve; Priit Palta; Marko Salmi; Sirpa Jalkanen; Ari Ahola-Olli; Aarno Palotie; Veikko Salomaa; Mark J. Daly; Matti Pirinen; Samuli Ripatti; Jukka Koskela

doi:10.1038/s41431-020-00730-8

An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

Sanni E. Ruotsalainen, Juulia J. Partanen, Anna Cichonska, Jake Lin, Christian Benner, Ida Surakka, Mary Pat Reeve, Priit Palta, Marko Salmi, Sirpa Jalkanen, Ari Ahola-Olli, Aarno Palotie, Veikko Salomaa, Mark J. Daly, Matti Pirinen, Samuli Ripatti, Jukka Koskela

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	European Journal of Human Genetics
Volume	29
Pages (from-to)	309–324
Number of pages	16
ISSN	1018-4813
DOIs	https://doi.org/10.1038/s41431-020-00730-8
Publication status	Published - Feb 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

1184 Genetics, developmental biology, physiology
IMPROVED IMPUTATION ACCURACY
GENOME-WIDE ASSOCIATION
PHASE-II TRIAL
HYPERTROPHIC SCARS
GROWTH-FACTOR
EXPRESSION
ANGIOGENESIS
MENINGIOMAS
RECURRENT
PDGF

Access to Document

10.1038/s41431-020-00730-8

ManuscriptAccepted author manuscript, 679 KB

Cite this

Ruotsalainen, S. E., Partanen, J. J., Cichonska, A., Lin, J., Benner, C., Surakka, I., Reeve, M. P., Palta, P., Salmi, M., Jalkanen, S., Ahola-Olli, A., Palotie, A., Salomaa, V., Daly, M. J., Pirinen, M., Ripatti, S., & Koskela, J. (2021). An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease. European Journal of Human Genetics, 29, 309–324. https://doi.org/10.1038/s41431-020-00730-8

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keywords = "1184 Genetics, developmental biology, physiology, IMPROVED IMPUTATION ACCURACY, GENOME-WIDE ASSOCIATION, PHASE-II TRIAL, HYPERTROPHIC SCARS, GROWTH-FACTOR, EXPRESSION, ANGIOGENESIS, MENINGIOMAS, RECURRENT, PDGF",

author = "Ruotsalainen, {Sanni E.} and Partanen, {Juulia J.} and Anna Cichonska and Jake Lin and Christian Benner and Ida Surakka and Reeve, {Mary Pat} and Priit Palta and Marko Salmi and Sirpa Jalkanen and Ari Ahola-Olli and Aarno Palotie and Veikko Salomaa and Daly, {Mark J.} and Matti Pirinen and Samuli Ripatti and Jukka Koskela",

year = "2021",

month = feb,

doi = "10.1038/s41431-020-00730-8",

language = "English",

volume = "29",

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journal = "European Journal of Human Genetics",

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publisher = "Nature Publishing Group",

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Ruotsalainen, SE , Partanen, JJ, Cichonska, A, Lin, J, Benner, C, Surakka, I, Reeve, MP , Palta, P, Salmi, M, Jalkanen, S, Ahola-Olli, A, Palotie, A, Salomaa, V, Daly, MJ , Pirinen, M , Ripatti, S & Koskela, J 2021, 'An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease', European Journal of Human Genetics, vol. 29, pp. 309–324. https://doi.org/10.1038/s41431-020-00730-8

TY - JOUR

T1 - An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease

AU - Ruotsalainen, Sanni E.

AU - Partanen, Juulia J.

AU - Cichonska, Anna

AU - Lin, Jake

AU - Benner, Christian

AU - Surakka, Ida

AU - Reeve, Mary Pat

AU - Palta, Priit

AU - Salmi, Marko

AU - Jalkanen, Sirpa

AU - Ahola-Olli, Ari

AU - Palotie, Aarno

AU - Salomaa, Veikko

AU - Daly, Mark J.

AU - Pirinen, Matti

AU - Ripatti, Samuli

AU - Koskela, Jukka

PY - 2021/2

Y1 - 2021/2

KW - 1184 Genetics, developmental biology, physiology

KW - IMPROVED IMPUTATION ACCURACY

KW - GENOME-WIDE ASSOCIATION

KW - PHASE-II TRIAL

KW - HYPERTROPHIC SCARS

KW - GROWTH-FACTOR

KW - EXPRESSION

KW - ANGIOGENESIS

KW - MENINGIOMAS

KW - RECURRENT

KW - PDGF

U2 - 10.1038/s41431-020-00730-8

DO - 10.1038/s41431-020-00730-8

M3 - Article

SN - 1018-4813

VL - 29

SP - 309

EP - 324

JO - European Journal of Human Genetics

JF - European Journal of Human Genetics

ER -