An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants

Suvi Ravela; Leena Valmu; Mykola Domanskyy; Hannu Koistinen; Leena Kylänpää; Outi Lindström; Jakob Stenman; Esa Hämäläinen; Ulf-Håkan Stenman; Outi Itkonen

doi:10.1007/s00216-017-0803-y

An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants

Suvi Ravela, Leena Valmu, Mykola Domanskyy, Hannu Koistinen, Leena Kylänpää, Outi Lindström, Jakob Stenman, Esa Hämäläinen, Ulf-Håkan Stenman, Outi Itkonen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Analytical and Bioanalytical Chemistry
Volume	410
Issue number	6
Pages (from-to)	1679-1688
Number of pages	10
ISSN	1618-2642
DOIs	https://doi.org/10.1007/s00216-017-0803-y
Publication status	Published - Feb 2018
MoE publication type	A1 Journal article-refereed

Fields of Science

Immunocapture
TATI
SPINK1
Quantitative LC-MS assay
CHRONIC-PANCREATITIS
MUTATIONS
GENE
N34S
3111 Biomedicine

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Ravela, S., Valmu, L., Domanskyy, M., Koistinen, H., Kylänpää, L., Lindström, O., Stenman, J., Hämäläinen, E., Stenman, U.-H., & Itkonen, O. (2018). An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants. Analytical and Bioanalytical Chemistry, 410(6), 1679-1688. https://doi.org/10.1007/s00216-017-0803-y

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Ravela, S, Valmu, L, Domanskyy, M, Koistinen, H, Kylänpää, L, Lindström, O, Stenman, J, Hämäläinen, E, Stenman, U-H & Itkonen, O 2018, 'An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants', Analytical and Bioanalytical Chemistry, vol. 410, no. 6, pp. 1679-1688. https://doi.org/10.1007/s00216-017-0803-y

TY - JOUR

T1 - An immunocapture-LC-MS-based assay for serum SPINK1 allows simultaneous quantification and detection of SPINK1 variants

AU - Ravela, Suvi

AU - Valmu, Leena

AU - Domanskyy, Mykola

AU - Koistinen, Hannu

AU - Kylänpää, Leena

AU - Lindström, Outi

AU - Stenman, Jakob

AU - Hämäläinen, Esa

AU - Stenman, Ulf-Håkan

AU - Itkonen, Outi

PY - 2018/2

Y1 - 2018/2

KW - Immunocapture

KW - TATI

KW - SPINK1

KW - Quantitative LC-MS assay

KW - CHRONIC-PANCREATITIS

KW - MUTATIONS

KW - GENE

KW - N34S

KW - 3111 Biomedicine

U2 - 10.1007/s00216-017-0803-y

DO - 10.1007/s00216-017-0803-y

M3 - Article

SN - 1618-2642

VL - 410

SP - 1679

EP - 1688

JO - Analytical and Bioanalytical Chemistry

JF - Analytical and Bioanalytical Chemistry

IS - 6

ER -