Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation

Henriikka Kentala, Annika Koponen, Annukka M. Kivelä, Robert Andrews, ChunHei Li, You Zhou, Vesa M. Olkkonen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalFASEB Journal
Volume32
Issue number3
Pages (from-to)1281-1295
Number of pages15
ISSN0892-6638
DOIs
Publication statusPublished - Mar 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • CRISPR-Cas9
  • F-actin
  • interactome
  • OSBPL2
  • RNA sequencing
  • OXYSTEROL-BINDING-PROTEIN
  • CELLULAR CHOLESTEROL-METABOLISM
  • OSBP-RELATED PROTEIN-2
  • HEARING-LOSS
  • STEROL TRANSPORT
  • PLASMA-MEMBRANE
  • LIPID DROPLETS
  • EXPRESSION
  • ER
  • CELLS
  • 3111 Biomedicine
  • 1182 Biochemistry, cell and molecular biology

Cite this

Kentala, Henriikka ; Koponen, Annika ; Kivelä, Annukka M. ; Andrews, Robert ; Li, ChunHei ; Zhou, You ; Olkkonen, Vesa M. / Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation. In: FASEB Journal. 2018 ; Vol. 32, No. 3. pp. 1281-1295.
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title = "Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation",
keywords = "CRISPR-Cas9, F-actin, interactome, OSBPL2, RNA sequencing, OXYSTEROL-BINDING-PROTEIN, CELLULAR CHOLESTEROL-METABOLISM, OSBP-RELATED PROTEIN-2, HEARING-LOSS, STEROL TRANSPORT, PLASMA-MEMBRANE, LIPID DROPLETS, EXPRESSION, ER, CELLS, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology",
author = "Henriikka Kentala and Annika Koponen and Kivel{\"a}, {Annukka M.} and Robert Andrews and ChunHei Li and You Zhou and Olkkonen, {Vesa M.}",
year = "2018",
month = "3",
doi = "10.1096/fj.201700604R",
language = "English",
volume = "32",
pages = "1281--1295",
journal = "FASEB Journal",
issn = "0892-6638",
publisher = "Federation of American Societies for Experimental Biology",
number = "3",

}

Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation. / Kentala, Henriikka; Koponen, Annika; Kivelä, Annukka M.; Andrews, Robert; Li, ChunHei; Zhou, You; Olkkonen, Vesa M.

In: FASEB Journal, Vol. 32, No. 3, 03.2018, p. 1281-1295.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Analysis of ORP2-knockout hepatocytes uncovers a novel function in actin cytoskeletal regulation

AU - Kentala, Henriikka

AU - Koponen, Annika

AU - Kivelä, Annukka M.

AU - Andrews, Robert

AU - Li, ChunHei

AU - Zhou, You

AU - Olkkonen, Vesa M.

PY - 2018/3

Y1 - 2018/3

KW - CRISPR-Cas9

KW - F-actin

KW - interactome

KW - OSBPL2

KW - RNA sequencing

KW - OXYSTEROL-BINDING-PROTEIN

KW - CELLULAR CHOLESTEROL-METABOLISM

KW - OSBP-RELATED PROTEIN-2

KW - HEARING-LOSS

KW - STEROL TRANSPORT

KW - PLASMA-MEMBRANE

KW - LIPID DROPLETS

KW - EXPRESSION

KW - ER

KW - CELLS

KW - 3111 Biomedicine

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1096/fj.201700604R

DO - 10.1096/fj.201700604R

M3 - Article

VL - 32

SP - 1281

EP - 1295

JO - FASEB Journal

JF - FASEB Journal

SN - 0892-6638

IS - 3

ER -