Projects per year
Abstract
Background: Self-reported angina symptoms are collected in epidemiological surveys.We aimed at validating the angina symptoms assessed by the Rose Questionnaire against registry data on coronary heart disease. A further aim was to examine the sex paradox in angina implying that women report more symptoms, whereas men have more coronary events.
Design: Angina symptoms of 6601 employees of the City of Helsinki were examined using the postal questionnaire survey data combined with coronary heart disease registries. Methods: The self-reported angina was classified as no symptoms, atypical pain, exertional chest pain, and stable angina symptoms. Reimbursed medications and hospital admissions were available from registries 10 years before the survey. Binomial regression analysis was used.
Results: Stable angina symptoms were associated with hospital admissions and reimbursed medications [prevalence ratio (PR), 6.75; 95% confidence interval (CI), 4.56-9.99]. In addition, exertional chest pain (PR, 5.31; 95% CI, 3.45-8.18) was associated with coronary events. All events were more prevalent among men than women (PR, 2.36; 95% CI, 1.72-3.25).
Conclusions: The Rose Questionnaire remains a valid tool to distinguish healthy people from those with coronary heart disease. However, a notable part of those reporting symptoms have no confirmation of coronary heart disease in the registries. The female excess of symptoms and male excess of events may reflect inequality or delay in access to treatment, problems in identification and diagnosis, or more complex issues related to self-reported angina symptoms.
Design: Angina symptoms of 6601 employees of the City of Helsinki were examined using the postal questionnaire survey data combined with coronary heart disease registries. Methods: The self-reported angina was classified as no symptoms, atypical pain, exertional chest pain, and stable angina symptoms. Reimbursed medications and hospital admissions were available from registries 10 years before the survey. Binomial regression analysis was used.
Results: Stable angina symptoms were associated with hospital admissions and reimbursed medications [prevalence ratio (PR), 6.75; 95% confidence interval (CI), 4.56-9.99]. In addition, exertional chest pain (PR, 5.31; 95% CI, 3.45-8.18) was associated with coronary events. All events were more prevalent among men than women (PR, 2.36; 95% CI, 1.72-3.25).
Conclusions: The Rose Questionnaire remains a valid tool to distinguish healthy people from those with coronary heart disease. However, a notable part of those reporting symptoms have no confirmation of coronary heart disease in the registries. The female excess of symptoms and male excess of events may reflect inequality or delay in access to treatment, problems in identification and diagnosis, or more complex issues related to self-reported angina symptoms.
| Original language | English |
|---|---|
| Journal | European Journal of Cardiovascular Prevention & Rehabilitation |
| Volume | 18 |
| Issue number | 4 |
| Pages (from-to) | 621-626 |
| Number of pages | 6 |
| ISSN | 1741-8267 |
| DOIs | |
| Publication status | Published - 2011 |
| MoE publication type | A1 Journal article-refereed |
Fields of Science
- Angina
- coronary heart disease
- registries
- Rose Questionnaire
- validation
- HOSPITAL DISCHARGE REGISTER
- CORONARY-HEART-DISEASE
- ROSE QUESTIONNAIRE ANGINA
- RISK-FACTORS
- CHEST-PAIN
- FOLLOW-UP
- WOMEN
- MEN
- PREVALENCE
- VALIDITY
- 3142 Public health care science, environmental and occupational health
Projects
- 1 Active
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Helsinki Health Study
Lallukka, T. (Principal Investigator), Kouvonen, A. (Co-Principal Investigator), Rahkonen, O. (Project manager), Lahelma, E. (Participant), Lahti, J. (Participant), Harkko, J. (Participant), Heinonen, N. A. (Participant), Hiilamo, A. J. (Participant), Kanerva, N. (Participant), Karjala, A. K. (Participant), Martikainen, P. (CoIlaborator), Mauramo, E. (Participant), Mänty, M. (Participant), Pekkala, J. (Participant), Pietiläinen, O. (Participant), Piha, K. (Participant), Roos, E. (Participant), Nordquist, H. (Participant), Valkonen, J. H. (Participant), Salonsalmi, A. (Participant), Silventoinen, K. (CoIlaborator), Suur-Uski, J. (Participant), Svärd, A. (Participant), Kivimäki, M. (CoIlaborator), Marmot, M. (CoIlaborator), Sekine, M. (CoIlaborator), Blomgren, J. (Other), Karvonen, S. (Other), Laaksonen, M. (Other), Leino-Arjas, P. (Other), Etholén, A. J. (Participant), Vähäsarja, L. E. J. (Participant) & Päivärinne, V. (Participant)
01/01/2000 → …
Project: Research project