Antibiotic-Resistance Genes in Waste Water

Research output: Contribution to journalReview ArticleScientificpeer-review

Abstract

Waste water and waste water treatment plants can act as reservoirs and environmental suppliers of antibiotic resistance. They have also been proposed to be hotspots for horizontal gene transfer, enabling the spread of antibiotic resistance genes between different bacterial species. Waste water contains antibiotics, disinfectants, and metals which can form a selection pressure for antibiotic resistance, even in low concentrations. Our knowledge of antibiotic resistance in waste water has increased tremendously in the past few years with advances in the molecular methods available. However, there are still some gaps in our knowledge on the subject, such as how active is horizontal gene transfer in waste water and what is the role of the waste water treatment plant in the environmental resistome? The purpose of this review is to briefly describe some of the main methods for studying antibiotic resistance in waste waters and the latest research and main knowledge gaps on the issue. In addition, some future research directions are proposed.

Original languageEnglish
JournalTrends in Microbiology
Volume26
Issue number3
Pages (from-to)220-228
Number of pages9
ISSN0966-842X
DOIs
Publication statusPublished - Mar 2018
MoE publication typeA2 Review article in a scientific journal

Fields of Science

  • 1182 Biochemistry, cell and molecular biology
  • 1183 Plant biology, microbiology, virology
  • ANTIMICROBIAL RESISTANCE
  • ESCHERICHIA-COLI
  • TREATMENT PLANTS
  • BACTERIAL COMMUNITIES
  • HIGH-THROUGHPUT
  • TETRACYCLINE RESISTANCE
  • METAGENOMIC APPROACH
  • ACTIVATED-SLUDGE
  • DRINKING-WATER
  • SURFACE-WATER

Cite this

Karkman, Antti Valter ; Thuy Do, Thi ; Walsh, Fiona ; Virta, Marko Petri Juhani. / Antibiotic-Resistance Genes in Waste Water. In: Trends in Microbiology. 2018 ; Vol. 26, No. 3. pp. 220-228.
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title = "Antibiotic-Resistance Genes in Waste Water",
abstract = "Waste water and waste water treatment plants can act as reservoirs and environmental suppliers of antibiotic resistance. They have also been proposed to be hotspots for horizontal gene transfer, enabling the spread of antibiotic resistance genes between different bacterial species. Waste water contains antibiotics, disinfectants, and metals which can form a selection pressure for antibiotic resistance, even in low concentrations. Our knowledge of antibiotic resistance in waste water has increased tremendously in the past few years with advances in the molecular methods available. However, there are still some gaps in our knowledge on the subject, such as how active is horizontal gene transfer in waste water and what is the role of the waste water treatment plant in the environmental resistome? The purpose of this review is to briefly describe some of the main methods for studying antibiotic resistance in waste waters and the latest research and main knowledge gaps on the issue. In addition, some future research directions are proposed.",
keywords = "1182 Biochemistry, cell and molecular biology, 1183 Plant biology, microbiology, virology, ANTIMICROBIAL RESISTANCE, ESCHERICHIA-COLI, TREATMENT PLANTS, BACTERIAL COMMUNITIES, HIGH-THROUGHPUT, TETRACYCLINE RESISTANCE, METAGENOMIC APPROACH, ACTIVATED-SLUDGE, DRINKING-WATER, SURFACE-WATER",
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Antibiotic-Resistance Genes in Waste Water. / Karkman, Antti Valter; Thuy Do, Thi; Walsh, Fiona; Virta, Marko Petri Juhani.

In: Trends in Microbiology, Vol. 26, No. 3, 03.2018, p. 220-228.

Research output: Contribution to journalReview ArticleScientificpeer-review

TY - JOUR

T1 - Antibiotic-Resistance Genes in Waste Water

AU - Karkman, Antti Valter

AU - Thuy Do, Thi

AU - Walsh, Fiona

AU - Virta, Marko Petri Juhani

PY - 2018/3

Y1 - 2018/3

N2 - Waste water and waste water treatment plants can act as reservoirs and environmental suppliers of antibiotic resistance. They have also been proposed to be hotspots for horizontal gene transfer, enabling the spread of antibiotic resistance genes between different bacterial species. Waste water contains antibiotics, disinfectants, and metals which can form a selection pressure for antibiotic resistance, even in low concentrations. Our knowledge of antibiotic resistance in waste water has increased tremendously in the past few years with advances in the molecular methods available. However, there are still some gaps in our knowledge on the subject, such as how active is horizontal gene transfer in waste water and what is the role of the waste water treatment plant in the environmental resistome? The purpose of this review is to briefly describe some of the main methods for studying antibiotic resistance in waste waters and the latest research and main knowledge gaps on the issue. In addition, some future research directions are proposed.

AB - Waste water and waste water treatment plants can act as reservoirs and environmental suppliers of antibiotic resistance. They have also been proposed to be hotspots for horizontal gene transfer, enabling the spread of antibiotic resistance genes between different bacterial species. Waste water contains antibiotics, disinfectants, and metals which can form a selection pressure for antibiotic resistance, even in low concentrations. Our knowledge of antibiotic resistance in waste water has increased tremendously in the past few years with advances in the molecular methods available. However, there are still some gaps in our knowledge on the subject, such as how active is horizontal gene transfer in waste water and what is the role of the waste water treatment plant in the environmental resistome? The purpose of this review is to briefly describe some of the main methods for studying antibiotic resistance in waste waters and the latest research and main knowledge gaps on the issue. In addition, some future research directions are proposed.

KW - 1182 Biochemistry, cell and molecular biology

KW - 1183 Plant biology, microbiology, virology

KW - ANTIMICROBIAL RESISTANCE

KW - ESCHERICHIA-COLI

KW - TREATMENT PLANTS

KW - BACTERIAL COMMUNITIES

KW - HIGH-THROUGHPUT

KW - TETRACYCLINE RESISTANCE

KW - METAGENOMIC APPROACH

KW - ACTIVATED-SLUDGE

KW - DRINKING-WATER

KW - SURFACE-WATER

U2 - 10.1016/j.tim.2017.09.005

DO - 10.1016/j.tim.2017.09.005

M3 - Review Article

VL - 26

SP - 220

EP - 228

JO - Trends in Microbiology

JF - Trends in Microbiology

SN - 0966-842X

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ER -