Anticancer activity of the protein kinase C modulator HMI-1a3 in 2D and 3D cell culture models of androgen-responsive and androgen-unresponsive prostate cancer

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalFEBS open bio
Volume8
Issue number5
Pages (from-to)817-828
Number of pages12
ISSN2211-5463
DOIs
Publication statusPublished - May 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • drug development
  • prostate cancer
  • protein kinase C
  • senescence
  • ESTER-INDUCED APOPTOSIS
  • PKC-DELTA
  • 12-O-TETRADECANOYLPHORBOL-13-ACETATE-INDUCED APOPTOSIS
  • SENESCENCE
  • ACTIVATION
  • EXPRESSION
  • PATHWAY
  • DOMAIN
  • INHIBITION
  • PACLITAXEL
  • 1182 Biochemistry, cell and molecular biology
  • 317 Pharmacy

Cite this

@article{ab8f8661ada94c3797c95f22b41e7bcc,
title = "Anticancer activity of the protein kinase C modulator HMI-1a3 in 2D and 3D cell culture models of androgen-responsive and androgen-unresponsive prostate cancer",
keywords = "drug development, prostate cancer, protein kinase C, senescence, ESTER-INDUCED APOPTOSIS, PKC-DELTA, 12-O-TETRADECANOYLPHORBOL-13-ACETATE-INDUCED APOPTOSIS, SENESCENCE, ACTIVATION, EXPRESSION, PATHWAY, DOMAIN, INHIBITION, PACLITAXEL, 1182 Biochemistry, cell and molecular biology, 317 Pharmacy",
author = "Jantti, {Maria H.} and Virpi Talman and Kati R{\"a}s{\"a}nen and Ilari Tarvainen and Hannu Koistinen and Tuominen, {Raimo K.}",
year = "2018",
month = "5",
doi = "10.1002/2211-5463.12419",
language = "English",
volume = "8",
pages = "817--828",
journal = "FEBS open bio",
issn = "2211-5463",
publisher = "Wiley",
number = "5",

}

TY - JOUR

T1 - Anticancer activity of the protein kinase C modulator HMI-1a3 in 2D and 3D cell culture models of androgen-responsive and androgen-unresponsive prostate cancer

AU - Jantti, Maria H.

AU - Talman, Virpi

AU - Räsänen, Kati

AU - Tarvainen, Ilari

AU - Koistinen, Hannu

AU - Tuominen, Raimo K.

PY - 2018/5

Y1 - 2018/5

KW - drug development

KW - prostate cancer

KW - protein kinase C

KW - senescence

KW - ESTER-INDUCED APOPTOSIS

KW - PKC-DELTA

KW - 12-O-TETRADECANOYLPHORBOL-13-ACETATE-INDUCED APOPTOSIS

KW - SENESCENCE

KW - ACTIVATION

KW - EXPRESSION

KW - PATHWAY

KW - DOMAIN

KW - INHIBITION

KW - PACLITAXEL

KW - 1182 Biochemistry, cell and molecular biology

KW - 317 Pharmacy

U2 - 10.1002/2211-5463.12419

DO - 10.1002/2211-5463.12419

M3 - Article

VL - 8

SP - 817

EP - 828

JO - FEBS open bio

JF - FEBS open bio

SN - 2211-5463

IS - 5

ER -