Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro

Senem Merve Fred; Suvi Kuivanen; Hasan Ugurlu; Plinio Cabrera Casarotto; Lev Levanov; Kalle Saksela; Olli Vapalahti; Eero Castren

doi:10.3389/fphar.2021.755600

Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro

Senem Merve Fred, Suvi Kuivanen, Hasan Ugurlu, Plinio Cabrera Casarotto, Lev Levanov, Kalle Saksela, Olli Vapalahti, Eero Castren

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	755600
Journal	Frontiers in Pharmacology
Volume	12
Number of pages	15
ISSN	1663-9812
DOIs	https://doi.org/10.3389/fphar.2021.755600
Publication status	Published - 19 Jan 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

antidepressants (AD)
fluoxetine
SARS-CoV-2
alpha variant
beta variant
delta variant
RECEPTOR-BINDING DOMAIN
FUNCTIONAL INHIBITORS
SARS CORONAVIRUS
SIGMA-RECEPTORS
COVID VACCINES
KETAMINE
MUTATIONS
PROTECT
VIRUS
ACE2
3111 Biomedicine

Access to Document

10.3389/fphar.2021.755600

fphar-12-755600Final published version, 2.65 MBLicence: CC BY

Cite this

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title = "Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro",

keywords = "antidepressants (AD), fluoxetine, SARS-CoV-2, alpha variant, beta variant, delta variant, RECEPTOR-BINDING DOMAIN, FUNCTIONAL INHIBITORS, SARS CORONAVIRUS, SIGMA-RECEPTORS, COVID VACCINES, KETAMINE, MUTATIONS, PROTECT, VIRUS, ACE2, 3111 Biomedicine",

author = "Fred, {Senem Merve} and Suvi Kuivanen and Hasan Ugurlu and Casarotto, {Plinio Cabrera} and Lev Levanov and Kalle Saksela and Olli Vapalahti and Eero Castren",

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T1 - Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro

AU - Fred, Senem Merve

AU - Kuivanen, Suvi

AU - Ugurlu, Hasan

AU - Casarotto, Plinio Cabrera

AU - Levanov, Lev

AU - Saksela, Kalle

AU - Vapalahti, Olli

AU - Castren, Eero

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KW - fluoxetine

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KW - alpha variant

KW - beta variant

KW - delta variant

KW - RECEPTOR-BINDING DOMAIN

KW - FUNCTIONAL INHIBITORS

KW - SARS CORONAVIRUS

KW - SIGMA-RECEPTORS

KW - COVID VACCINES

KW - KETAMINE

KW - MUTATIONS

KW - PROTECT

KW - VIRUS

KW - ACE2

KW - 3111 Biomedicine

U2 - 10.3389/fphar.2021.755600

DO - 10.3389/fphar.2021.755600

M3 - Article

SN - 1663-9812

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JO - Frontiers in Pharmacology

JF - Frontiers in Pharmacology

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