Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

Plinio C. Casarotto; Mykhailo Girych; Senem M. Fred; Vera Kovaleva; Rafael Moliner; Giray Enkavi; Caroline Biojone; Cecilia Cannarozzo; Madhusmita Pryiadrashini Sahu; Katja Kaurinkoski; Cecilia A. Brunello; Anna Steinzeig; Frederike Winkel; Sudarshan Patil; Stefan Vestring; Tsvetan Serchov; Cassiano R. A. F. Diniz; Liina Laukkanen; Iseline Cardon; Hanna Antila; Tomasz Rog; Timo Petteri Piepponen; Clive R. Bramham; Claus Normann; Sari E. Lauri; Mart Saarma; Ilpo Vattulainen; Eero Castren

doi:10.1016/j.cell.2021.01.034

Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

Plinio C. Casarotto, Mykhailo Girych, Senem M. Fred, Vera Kovaleva, Rafael Moliner, Giray Enkavi, Caroline Biojone, Cecilia Cannarozzo, Madhusmita Pryiadrashini Sahu, Katja Kaurinkoski, Cecilia A. Brunello, Anna Steinzeig, Frederike Winkel, Sudarshan Patil, Stefan Vestring, Tsvetan Serchov, Cassiano R. A. F. Diniz, Liina Laukkanen, Iseline Cardon, Hanna AntilaTomasz Rog, Timo Petteri Piepponen, Clive R. Bramham, Claus Normann, Sari E. Lauri, Mart Saarma, Ilpo Vattulainen, Eero Castren

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Cell
Volume	184
Issue number	5
Pages (from-to)	1299-+
Number of pages	34
ISSN	0092-8674
DOIs	https://doi.org/10.1016/j.cell.2021.01.034
Publication status	Published - 4 Mar 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

1182 Biochemistry, cell and molecular biology

Access to Document

10.1016/j.cell.2021.01.034

1-s2.0-S0092867421000775-mainFinal published version, 7.76 MBLicence: CC BY

Cite this

Casarotto, P. C., Girych, M., Fred, S. M., Kovaleva, V., Moliner, R., Enkavi, G., Biojone, C., Cannarozzo, C., Sahu, M. P., Kaurinkoski, K., Brunello, C. A., Steinzeig, A., Winkel, F., Patil, S., Vestring, S., Serchov, T., Diniz, C. R. A. F., Laukkanen, L., Cardon, I., ... Castren, E. (2021). Antidepressant drugs act by directly binding to TRKB neurotrophin receptors. Cell, 184(5), 1299-+. https://doi.org/10.1016/j.cell.2021.01.034

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title = "Antidepressant drugs act by directly binding to TRKB neurotrophin receptors",

keywords = "1182 Biochemistry, cell and molecular biology",

author = "Casarotto, {Plinio C.} and Mykhailo Girych and Fred, {Senem M.} and Vera Kovaleva and Rafael Moliner and Giray Enkavi and Caroline Biojone and Cecilia Cannarozzo and Sahu, {Madhusmita Pryiadrashini} and Katja Kaurinkoski and Brunello, {Cecilia A.} and Anna Steinzeig and Frederike Winkel and Sudarshan Patil and Stefan Vestring and Tsvetan Serchov and Diniz, {Cassiano R. A. F.} and Liina Laukkanen and Iseline Cardon and Hanna Antila and Tomasz Rog and Piepponen, {Timo Petteri} and Bramham, {Clive R.} and Claus Normann and Lauri, {Sari E.} and Mart Saarma and Ilpo Vattulainen and Eero Castren",

year = "2021",

month = mar,

day = "4",

doi = "10.1016/j.cell.2021.01.034",

language = "English",

volume = "184",

pages = "1299--+",

journal = "Cell",

issn = "0092-8674",

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Casarotto, PC, Girych, M , Fred, SM , Kovaleva, V , Moliner, R , Enkavi, G, Biojone, C, Cannarozzo, C, Sahu, MP, Kaurinkoski, K, Brunello, CA, Steinzeig, A, Winkel, F, Patil, S, Vestring, S, Serchov, T, Diniz, CRAF, Laukkanen, L, Cardon, I, Antila, H, Rog, T, Piepponen, TP, Bramham, CR, Normann, C, Lauri, SE , Saarma, M , Vattulainen, I & Castren, E 2021, 'Antidepressant drugs act by directly binding to TRKB neurotrophin receptors', Cell, vol. 184, no. 5, pp. 1299-+. https://doi.org/10.1016/j.cell.2021.01.034

TY - JOUR

T1 - Antidepressant drugs act by directly binding to TRKB neurotrophin receptors

AU - Casarotto, Plinio C.

AU - Girych, Mykhailo

AU - Fred, Senem M.

AU - Kovaleva, Vera

AU - Moliner, Rafael

AU - Enkavi, Giray

AU - Biojone, Caroline

AU - Cannarozzo, Cecilia

AU - Sahu, Madhusmita Pryiadrashini

AU - Kaurinkoski, Katja

AU - Brunello, Cecilia A.

AU - Steinzeig, Anna

AU - Winkel, Frederike

AU - Patil, Sudarshan

AU - Vestring, Stefan

AU - Serchov, Tsvetan

AU - Diniz, Cassiano R. A. F.

AU - Laukkanen, Liina

AU - Cardon, Iseline

AU - Antila, Hanna

AU - Rog, Tomasz

AU - Piepponen, Timo Petteri

AU - Bramham, Clive R.

AU - Normann, Claus

AU - Lauri, Sari E.

AU - Saarma, Mart

AU - Vattulainen, Ilpo

AU - Castren, Eero

PY - 2021/3/4

Y1 - 2021/3/4

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1016/j.cell.2021.01.034

DO - 10.1016/j.cell.2021.01.034

M3 - Article

SN - 0092-8674

VL - 184

SP - 1299-+

JO - Cell

JF - Cell

IS - 5

ER -