Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN

Cassiano Ricardo Alves Faria Diniz, Plinio C. Casarotto, Senem M. Fred, Caroline Biojone, Eero Castrén, Sâmia R.L. Joca

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNeuropharmacology
Volume135
Pages (from-to)163-171
Number of pages9
ISSN0028-3908
DOIs
Publication statusPublished - Jun 2018
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Angiotensin receptor blocker
  • Losartan
  • TRKB
  • AGTR2
  • DEPRESSION
  • TYROSINE KINASE FYN
  • THERAPEUTIC OPPORTUNITIES
  • CAPTOPRIL
  • MESSENGER-RNA
  • MICE
  • NEUROTROPHIN RECEPTORS
  • RAT-BRAIN
  • STRESS
  • EXPRESSION
  • 3124 Neurology and psychiatry

Cite this

@article{680e526014ad4a3f845ee8e93d42251d,
title = "Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN",
keywords = "Angiotensin receptor blocker, Losartan, TRKB, AGTR2, DEPRESSION, TYROSINE KINASE FYN, THERAPEUTIC OPPORTUNITIES, CAPTOPRIL, MESSENGER-RNA, MICE, NEUROTROPHIN RECEPTORS, RAT-BRAIN, STRESS, EXPRESSION, 3124 Neurology and psychiatry",
author = "Diniz, {Cassiano Ricardo Alves Faria} and Casarotto, {Plinio C.} and Fred, {Senem M.} and Caroline Biojone and Eero Castr{\'e}n and Joca, {S{\^a}mia R.L.}",
year = "2018",
month = "6",
doi = "10.1016/j.neuropharm.2018.03.011",
language = "English",
volume = "135",
pages = "163--171",
journal = "Neuropharmacology",
issn = "0028-3908",
publisher = "Elsevier Scientific Publ. Co",

}

Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN. / Diniz, Cassiano Ricardo Alves Faria; Casarotto, Plinio C.; Fred, Senem M.; Biojone, Caroline; Castrén, Eero; Joca, Sâmia R.L.

In: Neuropharmacology, Vol. 135, 06.2018, p. 163-171.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN

AU - Diniz, Cassiano Ricardo Alves Faria

AU - Casarotto, Plinio C.

AU - Fred, Senem M.

AU - Biojone, Caroline

AU - Castrén, Eero

AU - Joca, Sâmia R.L.

PY - 2018/6

Y1 - 2018/6

KW - Angiotensin receptor blocker

KW - Losartan

KW - TRKB

KW - AGTR2

KW - DEPRESSION

KW - TYROSINE KINASE FYN

KW - THERAPEUTIC OPPORTUNITIES

KW - CAPTOPRIL

KW - MESSENGER-RNA

KW - MICE

KW - NEUROTROPHIN RECEPTORS

KW - RAT-BRAIN

KW - STRESS

KW - EXPRESSION

KW - 3124 Neurology and psychiatry

U2 - 10.1016/j.neuropharm.2018.03.011

DO - 10.1016/j.neuropharm.2018.03.011

M3 - Article

VL - 135

SP - 163

EP - 171

JO - Neuropharmacology

JF - Neuropharmacology

SN - 0028-3908

ER -