Antidepressant use and violent crimes among young people: a longitudinal examination of the Finnish 1987 birth cohort

Elina Hemminki, Marko Merikukka, Mika Gissler, Kristian Wahlbeck, Jukka Savolainen, Tiina Ristikari, Mikko Aaltonen

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Background The use of antidepressants, especially selective serotonin reuptake inhibitors (SSRIs), has been questioned due to poor efficacy and safety. We examined whether young violent offenders were more likely antidepressant users prior to their first violent offence than other young persons.Methods The study is a follow-up of children born in Finland in 1987 (n=59 120), linking national registers to each other using personal identity codes. Data on psychotropic drug use came from a register of reimbursed drugs and data on crimes from a register on court convictions (after the age of 14 years). Participants were followed until the age of 18 years, and for some analyses until the end of the follow-up (mean 21 years). To adjust for differences in background characteristics, regression analyses for antidepressant use were made, using the no-conviction group as the reference.Results Proportions of young people convicted by the age of 18 years were: 5% of boys (1.7% for violent crimes) and 1% (0.5%) of girls. Antidepressant use (both overall and for SSRIs) prior to violent crime was more common among those convicted than among those without convictions. Among boys with repeated violent crimes, it was also more common than among boys with non-violent crimes. Adjustment for differences in background characteristics decreased the associations between antidepressant use and violent crime, but did not eliminate them.Conclusions The results add further evidence for caution in prescribing antidepressants among young persons. It also calls for a reanalysis of violence measures in the original trial data.
Original languageEnglish
JournalJournal of Epidemiology & Community Health
Volume71
Issue number1
Pages (from-to)12-18
Number of pages7
ISSN0143-005X
DOIs
Publication statusPublished - Jan 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 3142 Public health care science, environmental and occupational health

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