Antidiarrhoeal property of the hydroethanolic extract of the flowering tops of Anthocephalus cadamba.

M. Ashraful Alam, Raushanara Akter, Nusrat Subhan, M. Mostafizur Rahman, Muntasir M. Majumder, Lutfun Nahar, Satyajit D. Sarker

Research output: Contribution to journalArticleScientificpeer-review

Abstract

The antidiarrhoeal property of the hydroethanolic extract of the fl owering tops of Anthocephalus cadamba was assessed on experimental animals. The dry hydroethanolic extract (250-500 mg/kg body mass, p.o.) exhibited a dose-dependent decrease in the total number of faecal droppings in castor oil-induced diarrhoea in mice. The extract also produced a signifi cant (p < 0.01) and dose-dependent reduction in intestinal fl uids accumulation and in the gastrointestinal transit from 64.59 % and 71.19% at doses of 250 and 500 mg/kg. The reduction rates were 37.85% and 74.91%, respectively, with the control and standard drug group.
Original languageEnglish
JournalRevista Brasileira de Farmacognosia
Volume18
Issue number2
Pages (from-to)155-159
ISSN0102-695X
Publication statusPublished - 2008
MoE publication typeA1 Journal article-refereed

Cite this

M. Ashraful Alam, Raushanara Akter, Nusrat Subhan, M. Mostafizur Rahman, Muntasir M. Majumder, Lutfun Nahar, Satyajit D. Sarker (2008). Antidiarrhoeal property of the hydroethanolic extract of the flowering tops of Anthocephalus cadamba. Revista Brasileira de Farmacognosia, 18(2), 155-159.
M. Ashraful Alam, Raushanara Akter, Nusrat Subhan, M. Mostafizur Rahman, Muntasir M. Majumder, Lutfun Nahar, Satyajit D. Sarker. / Antidiarrhoeal property of the hydroethanolic extract of the flowering tops of Anthocephalus cadamba. In: Revista Brasileira de Farmacognosia. 2008 ; Vol. 18, No. 2. pp. 155-159.
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abstract = "The antidiarrhoeal property of the hydroethanolic extract of the fl owering tops of Anthocephalus cadamba was assessed on experimental animals. The dry hydroethanolic extract (250-500 mg/kg body mass, p.o.) exhibited a dose-dependent decrease in the total number of faecal droppings in castor oil-induced diarrhoea in mice. The extract also produced a signifi cant (p < 0.01) and dose-dependent reduction in intestinal fl uids accumulation and in the gastrointestinal transit from 64.59 {\%} and 71.19{\%} at doses of 250 and 500 mg/kg. The reduction rates were 37.85{\%} and 74.91{\%}, respectively, with the control and standard drug group.",
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M. Ashraful Alam, Raushanara Akter, Nusrat Subhan, M. Mostafizur Rahman, Muntasir M. Majumder, Lutfun Nahar, Satyajit D. Sarker 2008, 'Antidiarrhoeal property of the hydroethanolic extract of the flowering tops of Anthocephalus cadamba.', Revista Brasileira de Farmacognosia, vol. 18, no. 2, pp. 155-159.

Antidiarrhoeal property of the hydroethanolic extract of the flowering tops of Anthocephalus cadamba. / M. Ashraful Alam, Raushanara Akter, Nusrat Subhan, M. Mostafizur Rahman, Muntasir M. Majumder, Lutfun Nahar, Satyajit D. Sarker.

In: Revista Brasileira de Farmacognosia, Vol. 18, No. 2, 2008, p. 155-159.

Research output: Contribution to journalArticleScientificpeer-review

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AB - The antidiarrhoeal property of the hydroethanolic extract of the fl owering tops of Anthocephalus cadamba was assessed on experimental animals. The dry hydroethanolic extract (250-500 mg/kg body mass, p.o.) exhibited a dose-dependent decrease in the total number of faecal droppings in castor oil-induced diarrhoea in mice. The extract also produced a signifi cant (p < 0.01) and dose-dependent reduction in intestinal fl uids accumulation and in the gastrointestinal transit from 64.59 % and 71.19% at doses of 250 and 500 mg/kg. The reduction rates were 37.85% and 74.91%, respectively, with the control and standard drug group.

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M. Ashraful Alam, Raushanara Akter, Nusrat Subhan, M. Mostafizur Rahman, Muntasir M. Majumder, Lutfun Nahar, Satyajit D. Sarker. Antidiarrhoeal property of the hydroethanolic extract of the flowering tops of Anthocephalus cadamba. Revista Brasileira de Farmacognosia. 2008;18(2):155-159.