Association of bovine respiratory disease with clinical status and acute phase proteins in calves

S Nikunen, Heidi Härtel, Toomas Orro, Erkki Neuvonen, Raili Tanskanen, S.-L Kivelä, Satu Sankari, P Aho, Satu Pyörälä, Hannu Saloniemi, Timo Soveri

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Eighty-four calves with respiratory disease from 18 herds in different parts of Finland were chosen for a study evaluating the capacity of different respiratory pathogens to cause changes in different acute phase protein concentrations, white blood cell (WBC) count and clinical signs. The selected acute phase proteins were fibrinogen, haptoglobin, serum amyloid-A, lipopolysaccharide binding protein and alpha 1-acid glycoprotein. From each calf, a paired blood sample was obtained for serological studies of bovine parainfluenza virus-3, bovine respiratory syncytial virus, bovine coronavirus, bovine adenovirus-3 and bovine adenovirus-7. Tracheobronchial lavage was performed to detect bacteria and mycoplasma. Isolation of Pasteurella multocida was associated with increased concentrations of all tested acute phase proteins. For other pathogens, no significant relationships were observed. No association was present between viral or bacterial findings and WBC count. (c) 2007 Elsevier Ltd. All rights reserved.
Original languageEnglish
JournalComparative Immunology, Microbiology and Infectious Diseases
Volume30
Issue number3
Pages (from-to)143-151
Number of pages9
ISSN0147-9571
DOIs
Publication statusPublished - 2007
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 413 Veterinary science
  • eläinlääketiede
  • eläintaudit
  • hengityselinten taudit
  • vasikat
  • nautakarja

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