Atomistic MD simulation reveals the mechanism by which CETP penetrates into HDL enabling lipid transfer from HDL to CETP

Geraldine Cilpa-Karhu, Matti Jauhiainen, Marja-Liisa Riekkola

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Lipid Research
Volume56
Issue number1
Pages (from-to)98-108
Number of pages11
ISSN0022-2275
DOIs
Publication statusPublished - Jan 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • atherosclerosis
  • cholesterol/trafficking
  • estrogen
  • high density lipoprotein/metabolism
  • lipid transfer protein
  • lipoproteins
  • cholesterol ester transfer protein
  • molecular dynamics
  • HIGH-DENSITY-LIPOPROTEIN
  • ESTER TRANSFER PROTEIN
  • COMPUTATIONAL-EXPERIMENTAL-APPROACH
  • MOLECULAR-DYNAMICS SIMULATIONS
  • FATTY-ACID ESTERS
  • CONSTANT-PRESSURE
  • HIGH-THROUGHPUT
  • CHOLESTEROL
  • BILAYER
  • MODEL
  • 1182 Biochemistry, cell and molecular biology
  • 116 Chemical sciences

Cite this

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title = "Atomistic MD simulation reveals the mechanism by which CETP penetrates into HDL enabling lipid transfer from HDL to CETP",
keywords = "atherosclerosis, cholesterol/trafficking, estrogen, high density lipoprotein/metabolism, lipid transfer protein, lipoproteins, cholesterol ester transfer protein, molecular dynamics, HIGH-DENSITY-LIPOPROTEIN, ESTER TRANSFER PROTEIN, COMPUTATIONAL-EXPERIMENTAL-APPROACH, MOLECULAR-DYNAMICS SIMULATIONS, FATTY-ACID ESTERS, CONSTANT-PRESSURE, HIGH-THROUGHPUT, CHOLESTEROL, BILAYER, MODEL, 1182 Biochemistry, cell and molecular biology, 116 Chemical sciences",
author = "Geraldine Cilpa-Karhu and Matti Jauhiainen and Marja-Liisa Riekkola",
year = "2015",
month = "1",
doi = "10.1194/jlr.M054288",
language = "English",
volume = "56",
pages = "98--108",
journal = "Journal of Lipid Research",
issn = "0022-2275",
publisher = "American Society for Biochemistry and Molecular Biology",
number = "1",

}

Atomistic MD simulation reveals the mechanism by which CETP penetrates into HDL enabling lipid transfer from HDL to CETP. / Cilpa-Karhu, Geraldine; Jauhiainen, Matti; Riekkola, Marja-Liisa.

In: Journal of Lipid Research, Vol. 56, No. 1, 01.2015, p. 98-108.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Atomistic MD simulation reveals the mechanism by which CETP penetrates into HDL enabling lipid transfer from HDL to CETP

AU - Cilpa-Karhu, Geraldine

AU - Jauhiainen, Matti

AU - Riekkola, Marja-Liisa

PY - 2015/1

Y1 - 2015/1

KW - atherosclerosis

KW - cholesterol/trafficking

KW - estrogen

KW - high density lipoprotein/metabolism

KW - lipid transfer protein

KW - lipoproteins

KW - cholesterol ester transfer protein

KW - molecular dynamics

KW - HIGH-DENSITY-LIPOPROTEIN

KW - ESTER TRANSFER PROTEIN

KW - COMPUTATIONAL-EXPERIMENTAL-APPROACH

KW - MOLECULAR-DYNAMICS SIMULATIONS

KW - FATTY-ACID ESTERS

KW - CONSTANT-PRESSURE

KW - HIGH-THROUGHPUT

KW - CHOLESTEROL

KW - BILAYER

KW - MODEL

KW - 1182 Biochemistry, cell and molecular biology

KW - 116 Chemical sciences

U2 - 10.1194/jlr.M054288

DO - 10.1194/jlr.M054288

M3 - Article

VL - 56

SP - 98

EP - 108

JO - Journal of Lipid Research

JF - Journal of Lipid Research

SN - 0022-2275

IS - 1

ER -