Avoiding the Pitfalls of siRNA Delivery to the Retinal Pigment Epithelium with Physiologically Relevant Cell Models

Eva Ramsay, Manuela Ravina, Sanjay Sarkhel, Sarah Hehir, Neil R. Cameron, Tanja Ilmarinen, Heli Skottman, Jrgen Kjems, Arto Urtti, Marika Ruponen, Astrid Subrizi

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number667
JournalPharmaceutics
Volume12
Issue number7
Number of pages17
ISSN1999-4923
DOIs
Publication statusPublished - Jul 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • siRNA delivery
  • polyplex
  • lipoplex
  • lipidoid
  • retinal pigment epithelium
  • physiologically relevant RPE cell model
  • melanin
  • melanosome
  • GENE DELIVERY
  • INTRACELLULAR TRAFFICKING
  • OXIDATIVE DAMAGE
  • INTERFERING RNA
  • IN-VITRO
  • INFLAMMATION
  • TRANSFECTION
  • MELANIN
  • DIFFERENTIATION
  • DEGENERATION
  • 317 Pharmacy

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