Bayesian refinement of association signals for 14 loci in 3 common diseases

Julian B. Maller; Gilean McVean; Jake Byrnes; Damjan Vukcevic; Kimmo Palin; Zhan Su; Joanna M. M. Howson; Adam Auton; Simon Myers; Andrew Morris; Matti Pirinen; Matthew A. Brown; Paul R. Burton; Mark J. Caulfield; Alastair Compston; Martin Farrall; Alistair S. Hall; Andrew T. Hattersley; Adrian V. S. Hill; Christopher G. Mathew; Marcus Pembrey; Jack Satsangi; Michael R. Stratton; Jane Worthington; Nick Craddock; Matthew Hurles; Willem Ouwehand; Miles Parkes; Nazneen Rahman; Audrey Duncanson; John A. Todd; Dominic P. Kwiatkowski; Nilesh J. Samani; Stephen C. L. Gough; Mark I. McCarthy; Panagiotis Deloukas; Peter Donnelly; Wellcome Trust Case Control Consor

doi:10.1038/ng.2435

Bayesian refinement of association signals for 14 loci in 3 common diseases

Julian B. Maller, Gilean McVean, Jake Byrnes, Damjan Vukcevic, Kimmo Palin, Zhan Su, Joanna M. M. Howson, Adam Auton, Simon Myers, Andrew Morris, Matti Pirinen, Matthew A. Brown, Paul R. Burton, Mark J. Caulfield, Alastair Compston, Martin Farrall, Alistair S. Hall, Andrew T. Hattersley, Adrian V. S. Hill, Christopher G. MathewMarcus Pembrey, Jack Satsangi, Michael R. Stratton, Jane Worthington, Nick Craddock, Matthew Hurles, Willem Ouwehand, Miles Parkes, Nazneen Rahman, Audrey Duncanson, John A. Todd, Dominic P. Kwiatkowski, Nilesh J. Samani, Stephen C. L. Gough, Mark I. McCarthy, Panagiotis Deloukas, Peter Donnelly, Wellcome Trust Case Control Consor

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Nature Genetics
Volume	44
Issue number	12
Pages (from-to)	1294-1301
Number of pages	8
ISSN	1061-4036
DOIs	https://doi.org/10.1038/ng.2435
Publication status	Published - Dec 2012
MoE publication type	A1 Journal article-refereed

Fields of Science

GENOME
318 Medical biotechnology
1184 Genetics, developmental biology, physiology

Access to Document

10.1038/ng.2435

Cite this

Maller, J. B., McVean, G., Byrnes, J., Vukcevic, D., Palin, K., Su, Z., Howson, J. M. M., Auton, A., Myers, S., Morris, A., Pirinen, M., Brown, M. A., Burton, P. R., Caulfield, M. J., Compston, A., Farrall, M., Hall, A. S., Hattersley, A. T., Hill, A. V. S., ... Wellcome Trust Case Control Consor (2012). Bayesian refinement of association signals for 14 loci in 3 common diseases. Nature Genetics, 44(12), 1294-1301. https://doi.org/10.1038/ng.2435

Maller, Julian B. ; McVean, Gilean ; Byrnes, Jake ; Vukcevic, Damjan ; Palin, Kimmo ; Su, Zhan ; Howson, Joanna M. M. ; Auton, Adam ; Myers, Simon ; Morris, Andrew ; Pirinen, Matti ; Brown, Matthew A. ; Burton, Paul R. ; Caulfield, Mark J. ; Compston, Alastair ; Farrall, Martin ; Hall, Alistair S. ; Hattersley, Andrew T. ; Hill, Adrian V. S. ; Mathew, Christopher G. ; Pembrey, Marcus ; Satsangi, Jack ; Stratton, Michael R. ; Worthington, Jane ; Craddock, Nick ; Hurles, Matthew ; Ouwehand, Willem ; Parkes, Miles ; Rahman, Nazneen ; Duncanson, Audrey ; Todd, John A. ; Kwiatkowski, Dominic P. ; Samani, Nilesh J. ; Gough, Stephen C. L. ; McCarthy, Mark I. ; Deloukas, Panagiotis ; Donnelly, Peter ; Wellcome Trust Case Control Consor. / Bayesian refinement of association signals for 14 loci in 3 common diseases. In: Nature Genetics. 2012 ; Vol. 44, No. 12. pp. 1294-1301.

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title = "Bayesian refinement of association signals for 14 loci in 3 common diseases",

keywords = "GENOME, 318 Medical biotechnology, 1184 Genetics, developmental biology, physiology",

author = "Maller, {Julian B.} and Gilean McVean and Jake Byrnes and Damjan Vukcevic and Kimmo Palin and Zhan Su and Howson, {Joanna M. M.} and Adam Auton and Simon Myers and Andrew Morris and Matti Pirinen and Brown, {Matthew A.} and Burton, {Paul R.} and Caulfield, {Mark J.} and Alastair Compston and Martin Farrall and Hall, {Alistair S.} and Hattersley, {Andrew T.} and Hill, {Adrian V. S.} and Mathew, {Christopher G.} and Marcus Pembrey and Jack Satsangi and Stratton, {Michael R.} and Jane Worthington and Nick Craddock and Matthew Hurles and Willem Ouwehand and Miles Parkes and Nazneen Rahman and Audrey Duncanson and Todd, {John A.} and Kwiatkowski, {Dominic P.} and Samani, {Nilesh J.} and Gough, {Stephen C. L.} and McCarthy, {Mark I.} and Panagiotis Deloukas and Peter Donnelly and {Wellcome Trust Case Control Consor}",

year = "2012",

month = dec,

doi = "10.1038/ng.2435",

language = "English",

volume = "44",

pages = "1294--1301",

journal = "Nature Genetics",

issn = "1061-4036",

publisher = "Nature Publishing Group",

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Maller, JB, McVean, G, Byrnes, J, Vukcevic, D, Palin, K, Su, Z, Howson, JMM, Auton, A, Myers, S, Morris, A, Pirinen, M, Brown, MA, Burton, PR, Caulfield, MJ, Compston, A, Farrall, M, Hall, AS, Hattersley, AT, Hill, AVS, Mathew, CG, Pembrey, M, Satsangi, J, Stratton, MR, Worthington, J, Craddock, N, Hurles, M, Ouwehand, W, Parkes, M, Rahman, N, Duncanson, A, Todd, JA, Kwiatkowski, DP, Samani, NJ, Gough, SCL, McCarthy, MI, Deloukas, P, Donnelly, P & Wellcome Trust Case Control Consor 2012, 'Bayesian refinement of association signals for 14 loci in 3 common diseases', Nature Genetics, vol. 44, no. 12, pp. 1294-1301. https://doi.org/10.1038/ng.2435

Bayesian refinement of association signals for 14 loci in 3 common diseases. / Maller, Julian B.; McVean, Gilean; Byrnes, Jake; Vukcevic, Damjan; Palin, Kimmo; Su, Zhan; Howson, Joanna M. M.; Auton, Adam; Myers, Simon; Morris, Andrew; Pirinen, Matti; Brown, Matthew A.; Burton, Paul R.; Caulfield, Mark J.; Compston, Alastair; Farrall, Martin; Hall, Alistair S.; Hattersley, Andrew T.; Hill, Adrian V. S.; Mathew, Christopher G.; Pembrey, Marcus; Satsangi, Jack; Stratton, Michael R.; Worthington, Jane; Craddock, Nick; Hurles, Matthew; Ouwehand, Willem; Parkes, Miles; Rahman, Nazneen; Duncanson, Audrey; Todd, John A.; Kwiatkowski, Dominic P.; Samani, Nilesh J.; Gough, Stephen C. L.; McCarthy, Mark I.; Deloukas, Panagiotis; Donnelly, Peter; Wellcome Trust Case Control Consor.

In: Nature Genetics, Vol. 44, No. 12, 12.2012, p. 1294-1301.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Bayesian refinement of association signals for 14 loci in 3 common diseases

AU - Maller, Julian B.

AU - McVean, Gilean

AU - Byrnes, Jake

AU - Vukcevic, Damjan

AU - Palin, Kimmo

AU - Su, Zhan

AU - Howson, Joanna M. M.

AU - Auton, Adam

AU - Myers, Simon

AU - Morris, Andrew

AU - Pirinen, Matti

AU - Brown, Matthew A.

AU - Burton, Paul R.

AU - Caulfield, Mark J.

AU - Compston, Alastair

AU - Farrall, Martin

AU - Hall, Alistair S.

AU - Hattersley, Andrew T.

AU - Hill, Adrian V. S.

AU - Mathew, Christopher G.

AU - Pembrey, Marcus

AU - Satsangi, Jack

AU - Stratton, Michael R.

AU - Worthington, Jane

AU - Craddock, Nick

AU - Hurles, Matthew

AU - Ouwehand, Willem

AU - Parkes, Miles

AU - Rahman, Nazneen

AU - Duncanson, Audrey

AU - Todd, John A.

AU - Kwiatkowski, Dominic P.

AU - Samani, Nilesh J.

AU - Gough, Stephen C. L.

AU - McCarthy, Mark I.

AU - Deloukas, Panagiotis

AU - Donnelly, Peter

AU - Wellcome Trust Case Control Consor

PY - 2012/12

Y1 - 2012/12

KW - GENOME

KW - 318 Medical biotechnology

KW - 1184 Genetics, developmental biology, physiology

U2 - 10.1038/ng.2435

DO - 10.1038/ng.2435

M3 - Article

VL - 44

SP - 1294

EP - 1301

JO - Nature Genetics

JF - Nature Genetics

SN - 1061-4036

IS - 12

ER -