BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

Toshiyuki Mizui; Yasuyuki Ishikawa; Haruko Kumanogoh; Maria Lume; Tomoya Matsumoto; Tomoko Hara; Shigeto Yamawaki; Masami Takahashi; Sadao Shiosaka; Chiaki Itami; Koichi Uegaki; Mart Saarma; Masami Kojima

doi:10.1073/pnas.1422336112

BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

Toshiyuki Mizui, Yasuyuki Ishikawa, Haruko Kumanogoh, Maria Lume, Tomoya Matsumoto, Tomoko Hara, Shigeto Yamawaki, Masami Takahashi, Sadao Shiosaka, Chiaki Itami, Koichi Uegaki, Mart Saarma, Masami Kojima

Institute of Biotechnology

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	112
Issue number	23
Pages (from-to)	E3067-E3074
Number of pages	8
ISSN	0027-8424
DOIs	https://doi.org/10.1073/pnas.1422336112
Publication status	Published - 2015
MoE publication type	A1 Journal article-refereed

Fields of Science

growth factor
pro-peptide
synaptic plasticity
polymorphism
neuron
LONG-TERM DEPRESSION
SYNAPTIC AMPA RECEPTORS
NEUROTROPHIC FACTOR
MEMBRANE INSERTION
SIGNALING PATHWAYS
MOLECULAR-CLONING
NMDA RECEPTORS
NEURONS
PLASTICITY
ACTIVATION
1182 Biochemistry, cell and molecular biology

Access to Document

10.1073/pnas.1422336112

Cite this

Mizui, T., Ishikawa, Y., Kumanogoh, H., Lume, M., Matsumoto, T., Hara, T., Yamawaki, S., Takahashi, M., Shiosaka, S., Itami, C., Uegaki, K., Saarma, M., & Kojima, M. (2015). BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met. Proceedings of the National Academy of Sciences of the United States of America, 112(23), E3067-E3074. https://doi.org/10.1073/pnas.1422336112

@article{bdb4c345c2794d4db1f20969f2f5548b,

title = "BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met",

keywords = "growth factor, pro-peptide, synaptic plasticity, polymorphism, neuron, LONG-TERM DEPRESSION, SYNAPTIC AMPA RECEPTORS, NEUROTROPHIC FACTOR, MEMBRANE INSERTION, SIGNALING PATHWAYS, MOLECULAR-CLONING, NMDA RECEPTORS, NEURONS, PLASTICITY, ACTIVATION, 1182 Biochemistry, cell and molecular biology",

author = "Toshiyuki Mizui and Yasuyuki Ishikawa and Haruko Kumanogoh and Maria Lume and Tomoya Matsumoto and Tomoko Hara and Shigeto Yamawaki and Masami Takahashi and Sadao Shiosaka and Chiaki Itami and Koichi Uegaki and Mart Saarma and Masami Kojima",

year = "2015",

doi = "10.1073/pnas.1422336112",

language = "English",

volume = "112",

pages = "E3067--E3074",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

issn = "0027-8424",

publisher = "National Academy of Sciences",

number = "23",

}

Mizui, T, Ishikawa, Y, Kumanogoh, H, Lume, M, Matsumoto, T, Hara, T, Yamawaki, S, Takahashi, M, Shiosaka, S, Itami, C, Uegaki, K, Saarma, M & Kojima, M 2015, 'BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met', Proceedings of the National Academy of Sciences of the United States of America, vol. 112, no. 23, pp. E3067-E3074. https://doi.org/10.1073/pnas.1422336112

BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met. / Mizui, Toshiyuki; Ishikawa, Yasuyuki; Kumanogoh, Haruko et al.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, No. 23, 2015, p. E3067-E3074.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

AU - Mizui, Toshiyuki

AU - Ishikawa, Yasuyuki

AU - Kumanogoh, Haruko

AU - Lume, Maria

AU - Matsumoto, Tomoya

AU - Hara, Tomoko

AU - Yamawaki, Shigeto

AU - Takahashi, Masami

AU - Shiosaka, Sadao

AU - Itami, Chiaki

AU - Uegaki, Koichi

AU - Saarma, Mart

AU - Kojima, Masami

PY - 2015

Y1 - 2015

KW - growth factor

KW - pro-peptide

KW - synaptic plasticity

KW - polymorphism

KW - neuron

KW - LONG-TERM DEPRESSION

KW - SYNAPTIC AMPA RECEPTORS

KW - NEUROTROPHIC FACTOR

KW - MEMBRANE INSERTION

KW - SIGNALING PATHWAYS

KW - MOLECULAR-CLONING

KW - NMDA RECEPTORS

KW - NEURONS

KW - PLASTICITY

KW - ACTIVATION

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1073/pnas.1422336112

DO - 10.1073/pnas.1422336112

M3 - Article

SN - 0027-8424

VL - 112

SP - E3067-E3074

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

IS - 23

ER -