BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met

Toshiyuki Mizui, Yasuyuki Ishikawa, Haruko Kumanogoh, Maria Lume, Tomoya Matsumoto, Tomoko Hara, Shigeto Yamawaki, Masami Takahashi, Sadao Shiosaka, Chiaki Itami, Koichi Uegaki, Mart Saarma, Masami Kojima

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalProceedings of the National Academy of Sciences of the United States of America
Volume112
Issue number23
Pages (from-to)E3067-E3074
Number of pages8
ISSN0027-8424
DOIs
Publication statusPublished - 2015
MoE publication typeA1 Journal article-refereed

Fields of Science

  • growth factor
  • pro-peptide
  • synaptic plasticity
  • polymorphism
  • neuron
  • LONG-TERM DEPRESSION
  • SYNAPTIC AMPA RECEPTORS
  • NEUROTROPHIC FACTOR
  • MEMBRANE INSERTION
  • SIGNALING PATHWAYS
  • MOLECULAR-CLONING
  • NMDA RECEPTORS
  • NEURONS
  • PLASTICITY
  • ACTIVATION
  • 1182 Biochemistry, cell and molecular biology

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