Biotin IgM Antibodies in Human Blood: A Previously Unknown Factor Eliciting False Results in Biotinylation-Based Immunoassays

Tingting Chen; Lea Hedman; Petri S. Mattila; Laura Jartti; Tuomas Jartti; Olli Ruuskanen; Maria Söderlund-Venermo; Klaus Hedman

doi:10.1371/journal.pone.0042376

Biotin IgM Antibodies in Human Blood: A Previously Unknown Factor Eliciting False Results in Biotinylation-Based Immunoassays

Tingting Chen, Lea Hedman, Petri S. Mattila, Laura Jartti, Tuomas Jartti, Olli Ruuskanen, Maria Söderlund-Venermo, Klaus Hedman

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	PLoS One
Volume	7
Issue number	8
Pages (from-to)	Article Number: e42376
Number of pages	8
ISSN	1932-6203
DOIs	https://doi.org/10.1371/journal.pone.0042376
Publication status	Published - 2012
MoE publication type	A1 Journal article-refereed

Fields of Science

3111 Biomedicine

Cite this

Chen, T., Hedman, L., Mattila, P. S., Jartti, L., Jartti, T., Ruuskanen, O., ... Hedman, K. (2012). Biotin IgM Antibodies in Human Blood: A Previously Unknown Factor Eliciting False Results in Biotinylation-Based Immunoassays. PLoS One, 7(8), Article Number: e42376. https://doi.org/10.1371/journal.pone.0042376

@article{e284e666bad24f65a06a41003bdb7c64,

title = "Biotin IgM Antibodies in Human Blood: A Previously Unknown Factor Eliciting False Results in Biotinylation-Based Immunoassays",

keywords = "LINKED-IMMUNOSORBENT-ASSAY, MONOREACTIVE HIGH-AFFINITY, BINDING, IMMUNOGLOBULIN-G, B-CELL REPERTOIRE, EGG-WHITE POWDER, RHEUMATOID-FACTOR, AUTOANTIBODIES, DEFICIENCY, SERA, QUANTITATION, Life Sciences & Biomedicine - Other Topics, 3111 Biomedicine",

author = "Tingting Chen and Lea Hedman and Mattila, {Petri S.} and Laura Jartti and Tuomas Jartti and Olli Ruuskanen and Maria S{\"o}derlund-Venermo and Klaus Hedman",

year = "2012",

doi = "10.1371/journal.pone.0042376",

language = "English",

volume = "7",

pages = "Article Number: e42376",

journal = "PLoS One",

issn = "1932-6203",

publisher = "PUBLIC LIBRARY OF SCIENCE",

number = "8",

}

Biotin IgM Antibodies in Human Blood: A Previously Unknown Factor Eliciting False Results in Biotinylation-Based Immunoassays. / Chen, Tingting; Hedman, Lea ; Mattila, Petri S.; Jartti, Laura; Jartti, Tuomas; Ruuskanen, Olli; Söderlund-Venermo, Maria ; Hedman, Klaus.

In: PLoS One, Vol. 7, No. 8, 2012, p. Article Number: e42376.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Biotin IgM Antibodies in Human Blood: A Previously Unknown Factor Eliciting False Results in Biotinylation-Based Immunoassays

AU - Chen, Tingting

AU - Hedman, Lea

AU - Mattila, Petri S.

AU - Jartti, Laura

AU - Jartti, Tuomas

AU - Ruuskanen, Olli

AU - Söderlund-Venermo, Maria

AU - Hedman, Klaus

PY - 2012

Y1 - 2012

KW - LINKED-IMMUNOSORBENT-ASSAY

KW - MONOREACTIVE HIGH-AFFINITY

KW - BINDING

KW - IMMUNOGLOBULIN-G

KW - B-CELL REPERTOIRE

KW - EGG-WHITE POWDER

KW - RHEUMATOID-FACTOR

KW - AUTOANTIBODIES

KW - DEFICIENCY

KW - SERA

KW - QUANTITATION

KW - Life Sciences & Biomedicine - Other Topics

KW - 3111 Biomedicine

U2 - 10.1371/journal.pone.0042376

DO - 10.1371/journal.pone.0042376

M3 - Article

VL - 7

SP - Article Number: e42376

JO - PLoS One

JF - PLoS One

SN - 1932-6203

IS - 8

ER -

Access to Document

10.1371/journal.pone.0042376

Biotin IgM antibodies in human blood a previously unknown factor eliciting false results in biotinylation-based immunoassaysFinal published version, 856 KB