Brief Isoflurane Anesthesia Produces Prominent Phosphoproteomic Changes in the Adult Mouse Hippocampus

Samuel Kohtala, Wiebke Theilmann, Tomi Suomi, Henna-Kaisa Wigren, Tarja Porkka-Heiskanen, Laura L. Elo, Anne Rokka, Tomi Rantamaki

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalACS chemical neuroscience
Volume7
Issue number6
Pages (from-to)749-756
Number of pages8
ISSN1948-7193
DOIs
Publication statusPublished - Jun 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Anesthesia
  • protein phosphorylation
  • phosphopeptide enrichment
  • quantitative phosphoproteomics
  • glycogen synthase kinase-3 beta
  • MICROTUBULE-ASSOCIATED PROTEIN-2
  • GLYCOGEN-SYNTHASE KINASE-3
  • HCN1 CHANNELS CONTRIBUTE
  • BURST-SUPPRESSION
  • NEURONAL FUNCTION
  • ION-CHANNELS
  • PHOSPHORYLATION
  • CALCIUM
  • BRAIN
  • NARCOTHERAPY
  • 3112 Neurosciences
  • 3126 Surgery, anesthesiology, intensive care, radiology

Cite this

Kohtala, Samuel ; Theilmann, Wiebke ; Suomi, Tomi ; Wigren, Henna-Kaisa ; Porkka-Heiskanen, Tarja ; Elo, Laura L. ; Rokka, Anne ; Rantamaki, Tomi. / Brief Isoflurane Anesthesia Produces Prominent Phosphoproteomic Changes in the Adult Mouse Hippocampus. In: ACS chemical neuroscience. 2016 ; Vol. 7, No. 6. pp. 749-756.
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title = "Brief Isoflurane Anesthesia Produces Prominent Phosphoproteomic Changes in the Adult Mouse Hippocampus",
keywords = "Anesthesia, protein phosphorylation, phosphopeptide enrichment, quantitative phosphoproteomics, glycogen synthase kinase-3 beta, MICROTUBULE-ASSOCIATED PROTEIN-2, GLYCOGEN-SYNTHASE KINASE-3, HCN1 CHANNELS CONTRIBUTE, BURST-SUPPRESSION, NEURONAL FUNCTION, ION-CHANNELS, PHOSPHORYLATION, CALCIUM, BRAIN, NARCOTHERAPY, 3112 Neurosciences, 3126 Surgery, anesthesiology, intensive care, radiology",
author = "Samuel Kohtala and Wiebke Theilmann and Tomi Suomi and Henna-Kaisa Wigren and Tarja Porkka-Heiskanen and Elo, {Laura L.} and Anne Rokka and Tomi Rantamaki",
year = "2016",
month = "6",
doi = "10.1021/acschemneuro.6b00002",
language = "English",
volume = "7",
pages = "749--756",
journal = "ACS chemical neuroscience",
issn = "1948-7193",
publisher = "American Chemical Society",
number = "6",

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Brief Isoflurane Anesthesia Produces Prominent Phosphoproteomic Changes in the Adult Mouse Hippocampus. / Kohtala, Samuel; Theilmann, Wiebke; Suomi, Tomi; Wigren, Henna-Kaisa; Porkka-Heiskanen, Tarja; Elo, Laura L.; Rokka, Anne; Rantamaki, Tomi.

In: ACS chemical neuroscience, Vol. 7, No. 6, 06.2016, p. 749-756.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Brief Isoflurane Anesthesia Produces Prominent Phosphoproteomic Changes in the Adult Mouse Hippocampus

AU - Kohtala, Samuel

AU - Theilmann, Wiebke

AU - Suomi, Tomi

AU - Wigren, Henna-Kaisa

AU - Porkka-Heiskanen, Tarja

AU - Elo, Laura L.

AU - Rokka, Anne

AU - Rantamaki, Tomi

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KW - Anesthesia

KW - protein phosphorylation

KW - phosphopeptide enrichment

KW - quantitative phosphoproteomics

KW - glycogen synthase kinase-3 beta

KW - MICROTUBULE-ASSOCIATED PROTEIN-2

KW - GLYCOGEN-SYNTHASE KINASE-3

KW - HCN1 CHANNELS CONTRIBUTE

KW - BURST-SUPPRESSION

KW - NEURONAL FUNCTION

KW - ION-CHANNELS

KW - PHOSPHORYLATION

KW - CALCIUM

KW - BRAIN

KW - NARCOTHERAPY

KW - 3112 Neurosciences

KW - 3126 Surgery, anesthesiology, intensive care, radiology

U2 - 10.1021/acschemneuro.6b00002

DO - 10.1021/acschemneuro.6b00002

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VL - 7

SP - 749

EP - 756

JO - ACS chemical neuroscience

JF - ACS chemical neuroscience

SN - 1948-7193

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