Brief isoflurane anesthesia regulates striatal AKT-GSK3 beta signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease

Juuso V. Leikas, Samuel Kohtala, Wiebke Theilmann, Aaro J. Jalkanen, Markus M. Forsberg, Tomi Rantamaki

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalJournal of Neurochemistry
Volume142
Issue number3
Pages (from-to)456-463
Number of pages8
ISSN0022-3042
DOIs
Publication statusPublished - Aug 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • anesthesia
  • dopamine
  • neurodegeneration
  • phosphorylation
  • sensorimotor test
  • GLYCOGEN-SYNTHASE KINASE-3
  • ELECTROCONVULSIVE SHOCK
  • ALPHA-SYNUCLEIN
  • DOPAMINE
  • PHOSPHORYLATION
  • PATHWAY
  • BRAIN
  • NEUROPROTECTION
  • HIPPOCAMPUS
  • INHIBITION
  • 1182 Biochemistry, cell and molecular biology
  • 3112 Neurosciences

Cite this

@article{cfc2f9f116574a35b3f4083d7db05295,
title = "Brief isoflurane anesthesia regulates striatal AKT-GSK3 beta signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease",
keywords = "anesthesia, dopamine, neurodegeneration, phosphorylation, sensorimotor test, GLYCOGEN-SYNTHASE KINASE-3, ELECTROCONVULSIVE SHOCK, ALPHA-SYNUCLEIN, DOPAMINE, PHOSPHORYLATION, PATHWAY, BRAIN, NEUROPROTECTION, HIPPOCAMPUS, INHIBITION, 1182 Biochemistry, cell and molecular biology, 3112 Neurosciences",
author = "Leikas, {Juuso V.} and Samuel Kohtala and Wiebke Theilmann and Jalkanen, {Aaro J.} and Forsberg, {Markus M.} and Tomi Rantamaki",
year = "2017",
month = "8",
doi = "10.1111/jnc.14066",
language = "English",
volume = "142",
pages = "456--463",
journal = "Journal of Neurochemistry",
issn = "0022-3042",
publisher = "LIPPINCOTT-RAVEN PUBL",
number = "3",

}

Brief isoflurane anesthesia regulates striatal AKT-GSK3 beta signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease. / Leikas, Juuso V.; Kohtala, Samuel; Theilmann, Wiebke; Jalkanen, Aaro J.; Forsberg, Markus M.; Rantamaki, Tomi.

In: Journal of Neurochemistry, Vol. 142, No. 3, 08.2017, p. 456-463.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Brief isoflurane anesthesia regulates striatal AKT-GSK3 beta signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease

AU - Leikas, Juuso V.

AU - Kohtala, Samuel

AU - Theilmann, Wiebke

AU - Jalkanen, Aaro J.

AU - Forsberg, Markus M.

AU - Rantamaki, Tomi

PY - 2017/8

Y1 - 2017/8

KW - anesthesia

KW - dopamine

KW - neurodegeneration

KW - phosphorylation

KW - sensorimotor test

KW - GLYCOGEN-SYNTHASE KINASE-3

KW - ELECTROCONVULSIVE SHOCK

KW - ALPHA-SYNUCLEIN

KW - DOPAMINE

KW - PHOSPHORYLATION

KW - PATHWAY

KW - BRAIN

KW - NEUROPROTECTION

KW - HIPPOCAMPUS

KW - INHIBITION

KW - 1182 Biochemistry, cell and molecular biology

KW - 3112 Neurosciences

U2 - 10.1111/jnc.14066

DO - 10.1111/jnc.14066

M3 - Article

VL - 142

SP - 456

EP - 463

JO - Journal of Neurochemistry

JF - Journal of Neurochemistry

SN - 0022-3042

IS - 3

ER -