Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale

the SECRETO Study Group; Jukka Putaala; Nicolas Martinez-Majander; Michelle Leppert; Lauri Tulkki; Jani Pirinen; Heli Tolppanen; Tomi Sarkanen; Marko Virtanen; Nina Jaakonmäki; Pekka Jäkälä; Marja Hedman; Petra Redfors; Odd Bech-Hanssen; Ulla Junttola; Juha Huhtakangas; Pauli Ylikotila; Riikka Lautamäki; Ulf Schminke; Bettina Von Sarnowski; Raila Busch; Nilüfer Yesilot; Mine Sezgin; Ulrike Waje-Andreassen; Sahrai Saeed; Ana Catarina Fonseca; André Paula; Laura Amaya Pascasio; Patricia Martínez-Sánchez; Janika Kõrv; Piibe Muda; Phillip Ferdinand; Cheryl Oxley; Diana Zakarkaitė; Kristina Ryliškienė; Alessandro Pezzini; Carlo Mario Lombardi; Radim Licenik; Marialuisa Zedde; Teresa Grimaldi; Georgios Tsivgoulis; Juha Sinisalo; Eva Gerdts; Turgut Tatlisumak; Mika Lehto; Janne Rapola; Tiina Sairanen; Lauri Soinne; Satu Suihko; Marjaana Tiainen; Suvi Tuohinen

doi:10.1161/STROKEAHA.124.049855

Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale

the SECRETO Study Group, Jukka Putaala, Nicolas Martinez-Majander, Michelle Leppert, Lauri Tulkki, Jani Pirinen, Heli Tolppanen, Tomi Sarkanen, Marko Virtanen, Nina Jaakonmäki, Pekka Jäkälä, Marja Hedman, Petra Redfors, Odd Bech-Hanssen, Ulla Junttola, Juha Huhtakangas, Pauli Ylikotila, Riikka Lautamäki, Ulf Schminke, Bettina Von SarnowskiRaila Busch, Nilüfer Yesilot, Mine Sezgin, Ulrike Waje-Andreassen, Sahrai Saeed, Ana Catarina Fonseca, André Paula, Laura Amaya Pascasio, Patricia Martínez-Sánchez, Janika Kõrv, Piibe Muda, Phillip Ferdinand, Cheryl Oxley, Diana Zakarkaitė, Kristina Ryliškienė, Alessandro Pezzini, Carlo Mario Lombardi, Radim Licenik, Marialuisa Zedde, Teresa Grimaldi, Georgios Tsivgoulis, Juha Sinisalo, Eva Gerdts, Turgut Tatlisumak, Mika Lehto, Janne Rapola, Tiina Sairanen, Lauri Soinne, Satu Suihko, Marjaana Tiainen, Suvi Tuohinen

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Stroke
Volume	56
Issue number	6
Pages (from-to)	1428-1440
Number of pages	13
ISSN	0039-2499
DOIs	https://doi.org/10.1161/STROKEAHA.124.049855
Publication status	Published - 1 Jun 2025
MoE publication type	A1 Journal article-refereed

Bibliographical note

Publisher Copyright:
© 2025 The Authors. Stroke is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc.

Fields of Science

foramen ovale, patent
heart septal defects
ischemic stroke
migraine with aura
risk factors
3121 General medicine, internal medicine and other clinical medicine

Access to Document

10.1161/STROKEAHA.124.049855

putaala-et-al-burden-of-modifiable-risk-factors-in-young-onset-cryptogenic-ischemic-stroke-by-high-risk-patent-foramenFinal published version, 2.06 MBLicence: CC BY

Cite this

the SECRETO Study Group, Putaala, J., Martinez-Majander, N., Leppert, M., Tulkki, L., Pirinen, J., Tolppanen, H., Sarkanen, T., Virtanen, M., Jaakonmäki, N., Jäkälä, P., Hedman, M., Redfors, P., Bech-Hanssen, O., Junttola, U., Huhtakangas, J., Ylikotila, P., Lautamäki, R., Schminke, U., ... Tuohinen, S. (2025). Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale. Stroke, 56(6), 1428-1440. https://doi.org/10.1161/STROKEAHA.124.049855

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title = "Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale",

keywords = "foramen ovale, patent, heart septal defects, ischemic stroke, migraine with aura, risk factors, 3121 General medicine, internal medicine and other clinical medicine",

author = "{the SECRETO Study Group} and Jukka Putaala and Nicolas Martinez-Majander and Michelle Leppert and Lauri Tulkki and Jani Pirinen and Heli Tolppanen and Tomi Sarkanen and Marko Virtanen and Nina Jaakonm{\"a}ki and Pekka J{\"a}k{\"a}l{\"a} and Marja Hedman and Petra Redfors and Odd Bech-Hanssen and Ulla Junttola and Juha Huhtakangas and Pauli Ylikotila and Riikka Lautam{\"a}ki and Ulf Schminke and {Von Sarnowski}, Bettina and Raila Busch and Nil{\"u}fer Yesilot and Mine Sezgin and Ulrike Waje-Andreassen and Sahrai Saeed and Fonseca, {Ana Catarina} and Andr{\'e} Paula and {Amaya Pascasio}, Laura and Patricia Mart{\'i}nez-S{\'a}nchez and Janika K{\~o}rv and Piibe Muda and Phillip Ferdinand and Cheryl Oxley and Diana Zakarkaitė and Kristina Ryli{\v s}kienė and Alessandro Pezzini and Lombardi, {Carlo Mario} and Radim Licenik and Marialuisa Zedde and Teresa Grimaldi and Georgios Tsivgoulis and Juha Sinisalo and Eva Gerdts and Turgut Tatlisumak and Mika Lehto and Janne Rapola and Tiina Sairanen and Lauri Soinne and Satu Suihko and Marjaana Tiainen and Suvi Tuohinen",

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doi = "10.1161/STROKEAHA.124.049855",

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the SECRETO Study Group, Putaala, J , Martinez-Majander, N, Leppert, M, Tulkki, L , Pirinen, J , Tolppanen, H, Sarkanen, T, Virtanen, M, Jaakonmäki, N, Jäkälä, P, Hedman, M, Redfors, P, Bech-Hanssen, O, Junttola, U, Huhtakangas, J, Ylikotila, P, Lautamäki, R, Schminke, U, Von Sarnowski, B, Busch, R, Yesilot, N, Sezgin, M, Waje-Andreassen, U, Saeed, S, Fonseca, AC, Paula, A, Amaya Pascasio, L, Martínez-Sánchez, P, Kõrv, J, Muda, P, Ferdinand, P, Oxley, C, Zakarkaitė, D, Ryliškienė, K, Pezzini, A, Lombardi, CM, Licenik, R, Zedde, M, Grimaldi, T, Tsivgoulis, G, Sinisalo, J, Gerdts, E, Tatlisumak, T , Lehto, M, Rapola, J, Sairanen, T, Soinne, L , Suihko, S, Tiainen, M & Tuohinen, S 2025, 'Burden of Modifiable Risk Factors in Young-Onset Cryptogenic Ischemic Stroke by High-Risk Patent Foramen Ovale', Stroke, vol. 56, no. 6, pp. 1428-1440. https://doi.org/10.1161/STROKEAHA.124.049855

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AU - Putaala, Jukka

AU - Martinez-Majander, Nicolas

AU - Leppert, Michelle

AU - Tulkki, Lauri

AU - Pirinen, Jani

AU - Tolppanen, Heli

AU - Sarkanen, Tomi

AU - Virtanen, Marko

AU - Jaakonmäki, Nina

AU - Jäkälä, Pekka

AU - Hedman, Marja

AU - Redfors, Petra

AU - Bech-Hanssen, Odd

AU - Junttola, Ulla

AU - Huhtakangas, Juha

AU - Ylikotila, Pauli

AU - Lautamäki, Riikka

AU - Schminke, Ulf

AU - Von Sarnowski, Bettina

AU - Busch, Raila

AU - Yesilot, Nilüfer

AU - Sezgin, Mine

AU - Waje-Andreassen, Ulrike

AU - Saeed, Sahrai

AU - Fonseca, Ana Catarina

AU - Paula, André

AU - Amaya Pascasio, Laura

AU - Martínez-Sánchez, Patricia

AU - Kõrv, Janika

AU - Muda, Piibe

AU - Ferdinand, Phillip

AU - Oxley, Cheryl

AU - Zakarkaitė, Diana

AU - Ryliškienė, Kristina

AU - Pezzini, Alessandro

AU - Lombardi, Carlo Mario

AU - Licenik, Radim

AU - Zedde, Marialuisa

AU - Grimaldi, Teresa

AU - Tsivgoulis, Georgios

AU - Sinisalo, Juha

AU - Gerdts, Eva

AU - Tatlisumak, Turgut

AU - Lehto, Mika

AU - Rapola, Janne

AU - Sairanen, Tiina

AU - Soinne, Lauri

AU - Suihko, Satu

AU - Tiainen, Marjaana

AU - Tuohinen, Suvi

PY - 2025/6/1

Y1 - 2025/6/1

KW - foramen ovale, patent

KW - heart septal defects

KW - ischemic stroke

KW - migraine with aura

KW - risk factors

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1161/STROKEAHA.124.049855

DO - 10.1161/STROKEAHA.124.049855

M3 - Article

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SN - 0039-2499

VL - 56

SP - 1428

EP - 1440

JO - Stroke

JF - Stroke

IS - 6

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