C1 domain-targeted isophthalates as protein kinase C modulators

structure-based design, structure-activity relationships and biological activities

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBiochemical Society Transactions
Volume42
Issue number6
Pages (from-to)1543-1549
Number of pages7
ISSN0300-5127
DOIs
Publication statusPublished - Dec 2014
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Alzheimer's disease
  • antiproliferative
  • C1 domain
  • cancer
  • isophthalate
  • neurite growth protein kinase C
  • CONFORMATIONALLY CONSTRAINED ANALOGS
  • DIACYLGLYCEROL DAG
  • PHORBOL ESTER
  • PKC-ALPHA
  • NEUROBLASTOMA-CELLS
  • CATALYTIC DOMAIN
  • SH-SY5Y CELLS
  • BINDING
  • PHOSPHORYLATION
  • ACTIVATION
  • 317 Pharmacy

Cite this

@article{ad26e48bbbc744fbb99b96e1aaa897f2,
title = "C1 domain-targeted isophthalates as protein kinase C modulators: structure-based design, structure-activity relationships and biological activities",
keywords = "Alzheimer's disease, antiproliferative, C1 domain, cancer, isophthalate, neurite growth protein kinase C, CONFORMATIONALLY CONSTRAINED ANALOGS, DIACYLGLYCEROL DAG, PHORBOL ESTER, PKC-ALPHA, NEUROBLASTOMA-CELLS, CATALYTIC DOMAIN, SH-SY5Y CELLS, BINDING, PHOSPHORYLATION, ACTIVATION, 317 Pharmacy",
author = "Virpi Talman and Riccardo Provenzani and {af Genn{\"a}s}, {Gustav Boije} and Tuominen, {Raimo K.} and Jari Yli-Kauhaluoma",
year = "2014",
month = "12",
doi = "10.1042/BST20140181",
language = "English",
volume = "42",
pages = "1543--1549",
journal = "Biochemical Society Transactions",
issn = "0300-5127",
publisher = "Portland Press",
number = "6",

}

TY - JOUR

T1 - C1 domain-targeted isophthalates as protein kinase C modulators

T2 - structure-based design, structure-activity relationships and biological activities

AU - Talman, Virpi

AU - Provenzani, Riccardo

AU - af Gennäs, Gustav Boije

AU - Tuominen, Raimo K.

AU - Yli-Kauhaluoma, Jari

PY - 2014/12

Y1 - 2014/12

KW - Alzheimer's disease

KW - antiproliferative

KW - C1 domain

KW - cancer

KW - isophthalate

KW - neurite growth protein kinase C

KW - CONFORMATIONALLY CONSTRAINED ANALOGS

KW - DIACYLGLYCEROL DAG

KW - PHORBOL ESTER

KW - PKC-ALPHA

KW - NEUROBLASTOMA-CELLS

KW - CATALYTIC DOMAIN

KW - SH-SY5Y CELLS

KW - BINDING

KW - PHOSPHORYLATION

KW - ACTIVATION

KW - 317 Pharmacy

U2 - 10.1042/BST20140181

DO - 10.1042/BST20140181

M3 - Article

VL - 42

SP - 1543

EP - 1549

JO - Biochemical Society Transactions

JF - Biochemical Society Transactions

SN - 0300-5127

IS - 6

ER -