Characteristics of familial type 1 diabetes: effects of the relationship to the affected family member on phenotype and genotype at diagnosis

Maaret Turtinen, Taina Härkönen, Anna Parkkola, Jorma Ilonen, Mikael Knip, the Finnish Pediatric Diabetes Register

Research output: Contribution to journalArticleScientificpeer-review

Abstract

In previous studies, the risk of developing familial type 1 diabetes has been reported to be more than two times higher in the offspring of affected fathers than in those of affected mothers. We tested the hypothesis that index children with an affected father may have a more aggressive disease process at diagnosis than those with other affected first-degree relatives.
Original languageEnglish
JournalDiabetologia
ISSN1432-0428
DOIs
Publication statusPublished - 25 Jul 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 3121 Internal medicine

Cite this

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title = "Characteristics of familial type 1 diabetes: effects of the relationship to the affected family member on phenotype and genotype at diagnosis",
abstract = "In previous studies, the risk of developing familial type 1 diabetes has been reported to be more than two times higher in the offspring of affected fathers than in those of affected mothers. We tested the hypothesis that index children with an affected father may have a more aggressive disease process at diagnosis than those with other affected first-degree relatives.",
keywords = "3121 Internal medicine",
author = "Maaret Turtinen and Taina H{\"a}rk{\"o}nen and Anna Parkkola and Jorma Ilonen and Mikael Knip and Register, {the Finnish Pediatric Diabetes}",
year = "2019",
month = "7",
day = "25",
doi = "10.1007/s00125-019-4952-8",
language = "English",
journal = "Diabetologia",
issn = "0012-186X",
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Characteristics of familial type 1 diabetes: effects of the relationship to the affected family member on phenotype and genotype at diagnosis. / Turtinen, Maaret; Härkönen, Taina; Parkkola, Anna; Ilonen, Jorma; Knip, Mikael; Register, the Finnish Pediatric Diabetes.

In: Diabetologia, 25.07.2019.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Characteristics of familial type 1 diabetes: effects of the relationship to the affected family member on phenotype and genotype at diagnosis

AU - Turtinen, Maaret

AU - Härkönen, Taina

AU - Parkkola, Anna

AU - Ilonen, Jorma

AU - Knip, Mikael

AU - Register, the Finnish Pediatric Diabetes

PY - 2019/7/25

Y1 - 2019/7/25

N2 - In previous studies, the risk of developing familial type 1 diabetes has been reported to be more than two times higher in the offspring of affected fathers than in those of affected mothers. We tested the hypothesis that index children with an affected father may have a more aggressive disease process at diagnosis than those with other affected first-degree relatives.

AB - In previous studies, the risk of developing familial type 1 diabetes has been reported to be more than two times higher in the offspring of affected fathers than in those of affected mothers. We tested the hypothesis that index children with an affected father may have a more aggressive disease process at diagnosis than those with other affected first-degree relatives.

KW - 3121 Internal medicine

U2 - 10.1007/s00125-019-4952-8

DO - 10.1007/s00125-019-4952-8

M3 - Article

JO - Diabetologia

JF - Diabetologia

SN - 0012-186X

ER -