Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha/beta-hydrolase domain containing 11 (ABHD11)

Dina Navia-Paldanius, Jayendra Z. Patel, Miriam Lopez Navarro, Hermina Jakupovic, Steffi Goffart, Sanna Pasonen-Seppanen, Tapio J. Nevalainen, Tiina Jaaskelainen, Tuomo Laitinen, Jarmo T. Laitinen, Juha R. Savinainen

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalEuropean Journal of Pharmaceutical Sciences
Volume93
Pages (from-to)253-263
Number of pages11
ISSN0928-0987
DOIs
Publication statusPublished - 10 Oct 2016
Externally publishedYes
MoE publication typeA1 Journal article-refereed

Fields of Science

  • ABHD11
  • LYPLA2
  • AFMID
  • Serine hydrolases
  • ABPP
  • Inhibitor screening
  • Homology modelling
  • MONOACYLGLYCEROL LIPASE
  • PROSTATE-CANCER
  • TRIAZOLE UREAS
  • IDENTIFICATION
  • ENZYMES
  • THIOESTERASE
  • ULTRAPOTENT
  • ACTIVATION
  • HYDROLYSIS
  • PATHWAYS

Cite this

Navia-Paldanius, Dina ; Patel, Jayendra Z. ; Navarro, Miriam Lopez ; Jakupovic, Hermina ; Goffart, Steffi ; Pasonen-Seppanen, Sanna ; Nevalainen, Tapio J. ; Jaaskelainen, Tiina ; Laitinen, Tuomo ; Laitinen, Jarmo T. ; Savinainen, Juha R. / Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha/beta-hydrolase domain containing 11 (ABHD11). In: European Journal of Pharmaceutical Sciences. 2016 ; Vol. 93. pp. 253-263.
@article{a016ce63bb3b448688b8081958ee8d54,
title = "Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha/beta-hydrolase domain containing 11 (ABHD11)",
keywords = "ABHD11, LYPLA2, AFMID, Serine hydrolases, ABPP, Inhibitor screening, Homology modelling, MONOACYLGLYCEROL LIPASE, PROSTATE-CANCER, TRIAZOLE UREAS, IDENTIFICATION, ENZYMES, THIOESTERASE, ULTRAPOTENT, ACTIVATION, HYDROLYSIS, PATHWAYS",
author = "Dina Navia-Paldanius and Patel, {Jayendra Z.} and Navarro, {Miriam Lopez} and Hermina Jakupovic and Steffi Goffart and Sanna Pasonen-Seppanen and Nevalainen, {Tapio J.} and Tiina Jaaskelainen and Tuomo Laitinen and Laitinen, {Jarmo T.} and Savinainen, {Juha R.}",
year = "2016",
month = "10",
day = "10",
doi = "10.1016/j.ejps.2016.08.031",
language = "English",
volume = "93",
pages = "253--263",
journal = "European Journal of Pharmaceutical Sciences",
issn = "0928-0987",
publisher = "Elsevier Scientific Publ. Co",

}

Navia-Paldanius, D, Patel, JZ, Navarro, ML, Jakupovic, H, Goffart, S, Pasonen-Seppanen, S, Nevalainen, TJ, Jaaskelainen, T, Laitinen, T, Laitinen, JT & Savinainen, JR 2016, 'Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha/beta-hydrolase domain containing 11 (ABHD11)', European Journal of Pharmaceutical Sciences, vol. 93, pp. 253-263. https://doi.org/10.1016/j.ejps.2016.08.031

Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha/beta-hydrolase domain containing 11 (ABHD11). / Navia-Paldanius, Dina; Patel, Jayendra Z.; Navarro, Miriam Lopez; Jakupovic, Hermina; Goffart, Steffi; Pasonen-Seppanen, Sanna; Nevalainen, Tapio J.; Jaaskelainen, Tiina; Laitinen, Tuomo; Laitinen, Jarmo T.; Savinainen, Juha R.

In: European Journal of Pharmaceutical Sciences, Vol. 93, 10.10.2016, p. 253-263.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Chemoproteomic, biochemical and pharmacological approaches in the discovery of inhibitors targeting human alpha/beta-hydrolase domain containing 11 (ABHD11)

AU - Navia-Paldanius, Dina

AU - Patel, Jayendra Z.

AU - Navarro, Miriam Lopez

AU - Jakupovic, Hermina

AU - Goffart, Steffi

AU - Pasonen-Seppanen, Sanna

AU - Nevalainen, Tapio J.

AU - Jaaskelainen, Tiina

AU - Laitinen, Tuomo

AU - Laitinen, Jarmo T.

AU - Savinainen, Juha R.

PY - 2016/10/10

Y1 - 2016/10/10

KW - ABHD11

KW - LYPLA2

KW - AFMID

KW - Serine hydrolases

KW - ABPP

KW - Inhibitor screening

KW - Homology modelling

KW - MONOACYLGLYCEROL LIPASE

KW - PROSTATE-CANCER

KW - TRIAZOLE UREAS

KW - IDENTIFICATION

KW - ENZYMES

KW - THIOESTERASE

KW - ULTRAPOTENT

KW - ACTIVATION

KW - HYDROLYSIS

KW - PATHWAYS

U2 - 10.1016/j.ejps.2016.08.031

DO - 10.1016/j.ejps.2016.08.031

M3 - Article

VL - 93

SP - 253

EP - 263

JO - European Journal of Pharmaceutical Sciences

JF - European Journal of Pharmaceutical Sciences

SN - 0928-0987

ER -