Chemotherapy-induced gastrointestinal toxicity is associated with changes in serum and urine metabolome and fecal microbiota in male Sprague-Dawley rats

Richard A. Forsgard, Vannina G. Marrachelli, Katri Korpela, Rafael Frias, Maria Carmen Collado, Riitta Korpela, Daniel Monleon, Thomas Spillmann, Pia Osterlund

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalCancer Chemotherapy and Pharmacology
Volume80
Issue number2
Pages (from-to)317-332
Number of pages16
ISSN0344-5704
DOIs
Publication statusPublished - Aug 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Chemotherapy
  • Metabolomics
  • Microbiota
  • 5-FU
  • Oxaliplatin
  • Irinotecan
  • IRINOTECAN HYDROCHLORIDE CPT-11
  • BETA-GLUCURONIDASE
  • COLORECTAL-CANCER
  • INDUCED DIARRHEA
  • GUT MICROBIOTA
  • INTESTINAL PERMEABILITY
  • CROHNS-DISEASE
  • NITRIC-OXIDE
  • HUMAN BLOOD
  • MUCOSITIS
  • 3122 Cancers
  • 317 Pharmacy
  • 413 Veterinary science

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