Chemotherapy with Porous Silicon

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

Abstract

The current cancer chemotherapy offered to patients still suffers from severe side effects to off-target cells. In the recent years, a plethora of studies using porous silicon (PSi) as a micro/nano-vector for specific drug delivery and imaging diagnostic tool, has opened potential new avenues for the treatment of cancer diseases. In this context, PSi delivery systems that can specifically target cancer cells/tissues, precisely release the cargos, and even inducing immunostimulatory response for cancer immunotherapy, have also been demonstrated. PSi-based multifunctional systems encompassing both therapeutic and diagnostic functions have shown in real time the delivery of multi-payloads to the tumour site. In this chapter, the most recent selected PSi-based micro/nano-vectors for chemotherapy are revised and described. Relevant PSi formulations for chemotherapy are briefly summarized and the main results presented and discussed.
Original languageEnglish
Title of host publicationHandbook of Porous Silicon
EditorsLeigh Canham
Number of pages15
PublisherSpringer International Publishing
Publication date13 Dec 2016
ISBN (Print)978-3-319-04508-5
ISBN (Electronic)978-3-319-04508-5
DOIs
Publication statusPublished - 13 Dec 2016
MoE publication typeA3 Book chapter

Fields of Science

  • 116 Chemical sciences

Cite this

Almeida Santos, H. (2016). Chemotherapy with Porous Silicon. In L. Canham (Ed.), Handbook of Porous Silicon Springer International Publishing . https://doi.org/10.1007/978-3-319-04508-5_128-1
Almeida Santos, Helder. / Chemotherapy with Porous Silicon. Handbook of Porous Silicon. editor / Leigh Canham. Springer International Publishing , 2016.
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Almeida Santos, H 2016, Chemotherapy with Porous Silicon. in L Canham (ed.), Handbook of Porous Silicon. Springer International Publishing . https://doi.org/10.1007/978-3-319-04508-5_128-1

Chemotherapy with Porous Silicon. / Almeida Santos, Helder.

Handbook of Porous Silicon. ed. / Leigh Canham. Springer International Publishing , 2016.

Research output: Chapter in Book/Report/Conference proceedingChapterScientificpeer-review

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Almeida Santos H. Chemotherapy with Porous Silicon. In Canham L, editor, Handbook of Porous Silicon. Springer International Publishing . 2016 https://doi.org/10.1007/978-3-319-04508-5_128-1