Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue

Kai Rausalu; Age Utt; Tania Quirin; Finny S. Varghese; Eva Zusinaite; Pratyush Kumar Das; Tero Ahola; Andres Merits

doi:10.1038/srep37124

Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue

Kai Rausalu, Age Utt, Tania Quirin, Finny S. Varghese, Eva Zusinaite, Pratyush Kumar Das, Tero Ahola, Andres Merits

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	37124
Journal	Scientific Reports
Volume	6
Number of pages	17
ISSN	2045-2322
DOIs	https://doi.org/10.1038/srep37124
Publication status	Published - 15 Nov 2016
MoE publication type	A1 Journal article-refereed

Fields of Science

SEMLIKI-FOREST-VIRUS
SINDBIS VIRUS
TEMPORAL REGULATION
CLEAVAGE-SITE
PROTEIN NSP2
INHIBITORS
COMPLEX
IDENTIFICATION
DETERMINANTS
SPECIFICITY
3111 Biomedicine
416 Food Science

Access to Document

10.1038/srep37124

Chikungunya virus infectivityFinal published version, 3.21 MBLicence: CC BY

Cite this

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title = "Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue",

keywords = "SEMLIKI-FOREST-VIRUS, SINDBIS VIRUS, TEMPORAL REGULATION, CLEAVAGE-SITE, PROTEIN NSP2, INHIBITORS, COMPLEX, IDENTIFICATION, DETERMINANTS, SPECIFICITY, 3111 Biomedicine, 416 Food Science",

author = "Kai Rausalu and Age Utt and Tania Quirin and Varghese, {Finny S.} and Eva Zusinaite and Das, {Pratyush Kumar} and Tero Ahola and Andres Merits",

year = "2016",

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day = "15",

doi = "10.1038/srep37124",

language = "English",

volume = "6",

journal = "Scientific Reports",

issn = "2045-2322",

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T1 - Chikungunya virus infectivity, RNA replication and non-structural polyprotein processing depend on the nsP2 protease's active site cysteine residue

AU - Rausalu, Kai

AU - Utt, Age

AU - Quirin, Tania

AU - Varghese, Finny S.

AU - Zusinaite, Eva

AU - Das, Pratyush Kumar

AU - Ahola, Tero

AU - Merits, Andres

PY - 2016/11/15

Y1 - 2016/11/15

KW - SEMLIKI-FOREST-VIRUS

KW - SINDBIS VIRUS

KW - TEMPORAL REGULATION

KW - CLEAVAGE-SITE

KW - PROTEIN NSP2

KW - INHIBITORS

KW - COMPLEX

KW - IDENTIFICATION

KW - DETERMINANTS

KW - SPECIFICITY

KW - 3111 Biomedicine

KW - 416 Food Science

U2 - 10.1038/srep37124

DO - 10.1038/srep37124

M3 - Article

VL - 6

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 37124

ER -