Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

Kate Lawrenson; Qiyan Li; Siddhartha Kar; Ji-Heui Seo; Jonathan Tyrer; Tassja J. Spindler; Janet Lee; Yibu Chen; Alison Karst; Ronny Drapkin; Katja K. H. Aben; Hoda Anton-Culver; Natalia Antonenkova; Helen Baker; Elisa V. Bandera; Yukie Bean; Matthias W. Beckmann; Andrew Berchuck; Maria Bisogna; Line Bjorge; Natalia Bogdanova; Louise A. Brinton; Angela Brooks-Wilson; Fiona Bruinsma; Ralf Butzow; Ian G. Campbell; Karen Carty; Jenny Chang-Claude; Georgia Chenevix-Trench; Anne Chen; Zhihua Chen; Linda S. Cook; Daniel W. Cramer; Julie M. Cunningham; Cezary Cybulski; Agnieszka Dansonka-Mieszkowska; Joe Dennis; Ed Dicks; Jennifer A. Doherty; Thilo Doerk; Andreas Du Bois; Matthias Duerst; Diana Eccles; Douglas T. Easton; Robert P. Edwards; Ursula Eilber; Arif B. Ekici; Arto Leminen; Heli Nevanlinna; Liisa M. Pelttari; Australian Ovarian Canc Study Grp

doi:10.1038/ncomms9234

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

Kate Lawrenson, Qiyan Li, Siddhartha Kar, Ji-Heui Seo, Jonathan Tyrer, Tassja J. Spindler, Janet Lee, Yibu Chen, Alison Karst, Ronny Drapkin, Katja K. H. Aben, Hoda Anton-Culver, Natalia Antonenkova, Helen Baker, Elisa V. Bandera, Yukie Bean, Matthias W. Beckmann, Andrew Berchuck, Maria Bisogna, Line BjorgeNatalia Bogdanova, Louise A. Brinton, Angela Brooks-Wilson, Fiona Bruinsma, Ralf Butzow, Ian G. Campbell, Karen Carty, Jenny Chang-Claude, Georgia Chenevix-Trench, Anne Chen, Zhihua Chen, Linda S. Cook, Daniel W. Cramer, Julie M. Cunningham, Cezary Cybulski, Agnieszka Dansonka-Mieszkowska, Joe Dennis, Ed Dicks, Jennifer A. Doherty, Thilo Doerk, Andreas Du Bois, Matthias Duerst, Diana Eccles, Douglas T. Easton, Robert P. Edwards, Ursula Eilber, Arif B. Ekici, Arto Leminen, Heli Nevanlinna, Liisa M. Pelttari, Australian Ovarian Canc Study Grp

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	8234
Journal	Nature Communications
Volume	6
Number of pages	14
ISSN	2041-1723
DOIs	https://doi.org/10.1038/ncomms9234
Publication status	Published - Sept 2015
MoE publication type	A1 Journal article-refereed

Fields of Science

GENOME-WIDE ASSOCIATION
LONG-RANGE INTERACTION
ANALYSES REVEAL
FALLOPIAN-TUBE
RISK LOCI
HOX GENES
IDENTIFICATION
EXPRESSION
BREAST
VARIANTS
3111 Biomedicine
3123 Gynaecology and paediatrics

Access to Document

10.1038/ncomms9234

ncomms9234Final published version, 1.6 MBLicence: CC BY

Cite this

Lawrenson, K., Li, Q., Kar, S., Seo, J.-H., Tyrer, J., Spindler, T. J., Lee, J., Chen, Y., Karst, A., Drapkin, R., Aben, K. K. H., Anton-Culver, H., Antonenkova, N., Baker, H., Bandera, E. V., Bean, Y., Beckmann, M. W., Berchuck, A., Bisogna, M., ... Australian Ovarian Canc Study Grp (2015). Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer. Nature Communications, 6, Article 8234. https://doi.org/10.1038/ncomms9234

@article{351750e3ee1c443fbb72a69dafc56f2f,

title = "Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer",

keywords = "GENOME-WIDE ASSOCIATION, LONG-RANGE INTERACTION, ANALYSES REVEAL, FALLOPIAN-TUBE, RISK LOCI, HOX GENES, IDENTIFICATION, EXPRESSION, BREAST, VARIANTS, 3111 Biomedicine, 3123 Gynaecology and paediatrics",

author = "Kate Lawrenson and Qiyan Li and Siddhartha Kar and Ji-Heui Seo and Jonathan Tyrer and Spindler, {Tassja J.} and Janet Lee and Yibu Chen and Alison Karst and Ronny Drapkin and Aben, {Katja K. H.} and Hoda Anton-Culver and Natalia Antonenkova and Helen Baker and Bandera, {Elisa V.} and Yukie Bean and Beckmann, {Matthias W.} and Andrew Berchuck and Maria Bisogna and Line Bjorge and Natalia Bogdanova and Brinton, {Louise A.} and Angela Brooks-Wilson and Fiona Bruinsma and Ralf Butzow and Campbell, {Ian G.} and Karen Carty and Jenny Chang-Claude and Georgia Chenevix-Trench and Anne Chen and Zhihua Chen and Cook, {Linda S.} and Cramer, {Daniel W.} and Cunningham, {Julie M.} and Cezary Cybulski and Agnieszka Dansonka-Mieszkowska and Joe Dennis and Ed Dicks and Doherty, {Jennifer A.} and Thilo Doerk and {Du Bois}, Andreas and Matthias Duerst and Diana Eccles and Easton, {Douglas T.} and Edwards, {Robert P.} and Ursula Eilber and Ekici, {Arif B.} and Arto Leminen and Heli Nevanlinna and Pelttari, {Liisa M.} and {Australian Ovarian Canc Study Grp}",

year = "2015",

month = sep,

doi = "10.1038/ncomms9234",

language = "English",

volume = "6",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

}

Lawrenson, K, Li, Q, Kar, S, Seo, J-H, Tyrer, J, Spindler, TJ, Lee, J, Chen, Y, Karst, A, Drapkin, R, Aben, KKH, Anton-Culver, H, Antonenkova, N, Baker, H, Bandera, EV, Bean, Y, Beckmann, MW, Berchuck, A, Bisogna, M, Bjorge, L, Bogdanova, N, Brinton, LA, Brooks-Wilson, A, Bruinsma, F, Butzow, R, Campbell, IG, Carty, K, Chang-Claude, J, Chenevix-Trench, G, Chen, A, Chen, Z, Cook, LS, Cramer, DW, Cunningham, JM, Cybulski, C, Dansonka-Mieszkowska, A, Dennis, J, Dicks, E, Doherty, JA, Doerk, T, Du Bois, A, Duerst, M, Eccles, D, Easton, DT, Edwards, RP, Eilber, U, Ekici, AB, Leminen, A , Nevanlinna, H , Pelttari, LM & Australian Ovarian Canc Study Grp 2015, 'Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer', Nature Communications, vol. 6, 8234. https://doi.org/10.1038/ncomms9234

TY - JOUR

T1 - Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

AU - Lawrenson, Kate

AU - Li, Qiyan

AU - Kar, Siddhartha

AU - Seo, Ji-Heui

AU - Tyrer, Jonathan

AU - Spindler, Tassja J.

AU - Lee, Janet

AU - Chen, Yibu

AU - Karst, Alison

AU - Drapkin, Ronny

AU - Aben, Katja K. H.

AU - Anton-Culver, Hoda

AU - Antonenkova, Natalia

AU - Baker, Helen

AU - Bandera, Elisa V.

AU - Bean, Yukie

AU - Beckmann, Matthias W.

AU - Berchuck, Andrew

AU - Bisogna, Maria

AU - Bjorge, Line

AU - Bogdanova, Natalia

AU - Brinton, Louise A.

AU - Brooks-Wilson, Angela

AU - Bruinsma, Fiona

AU - Butzow, Ralf

AU - Campbell, Ian G.

AU - Carty, Karen

AU - Chang-Claude, Jenny

AU - Chenevix-Trench, Georgia

AU - Chen, Anne

AU - Chen, Zhihua

AU - Cook, Linda S.

AU - Cramer, Daniel W.

AU - Cunningham, Julie M.

AU - Cybulski, Cezary

AU - Dansonka-Mieszkowska, Agnieszka

AU - Dennis, Joe

AU - Dicks, Ed

AU - Doherty, Jennifer A.

AU - Doerk, Thilo

AU - Du Bois, Andreas

AU - Duerst, Matthias

AU - Eccles, Diana

AU - Easton, Douglas T.

AU - Edwards, Robert P.

AU - Eilber, Ursula

AU - Ekici, Arif B.

AU - Leminen, Arto

AU - Nevanlinna, Heli

AU - Pelttari, Liisa M.

AU - Australian Ovarian Canc Study Grp

PY - 2015/9

Y1 - 2015/9

KW - GENOME-WIDE ASSOCIATION

KW - LONG-RANGE INTERACTION

KW - ANALYSES REVEAL

KW - FALLOPIAN-TUBE

KW - RISK LOCI

KW - HOX GENES

KW - IDENTIFICATION

KW - EXPRESSION

KW - BREAST

KW - VARIANTS

KW - 3111 Biomedicine

KW - 3123 Gynaecology and paediatrics

U2 - 10.1038/ncomms9234

DO - 10.1038/ncomms9234

M3 - Article

SN - 2041-1723

VL - 6

JO - Nature Communications

JF - Nature Communications

M1 - 8234

ER -