CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia

William Grey, Ana Rio-Machin, Pedro Casado, Eva Gronroos, Sara Ali, Juho J. Miettinen, Findlay Bewicke-Copley, Alun Parsons, Caroline A. Heckman, Charles Swanton, Pedro R. Cutillas, John Gribben, Jude Fitzgibbon, Dominique Bonnet

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number3248
JournalScience translational medicine
Volume14
Issue number650
Number of pages14
ISSN1946-6234
DOIs
Publication statusPublished - 22 Jun 2022
MoE publication typeA1 Journal article-refereed

Fields of Science

  • SMALL-MOLECULE INHIBITORS
  • INTENSIVE CHEMOTHERAPY
  • SELF-RENEWAL
  • AML CELLS
  • OVEREXPRESSION
  • EXPRESSION
  • CANCER
  • PEVONEDISTAT
  • AZACITIDINE
  • VENETOCLAX
  • 1182 Biochemistry, cell and molecular biology

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