Clinical presentation and risk factors of placental abruption

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    Abstract

    "Background. To study the risk factors of placental abruption during the index pregnancy. Methods. One hundred and ninety-eight women with placental abruption and 396 control women were identified among 46,742 women who delivered at a tertiary referral university hospital between 1997 and 2001. Clinical variables were compared between the groups. Multivariate logistic regression analysis was applied to identify independent risk factors. The clinical manifestations of placental abruption were also studied. Results. The overall incidence of placental abruption was 0.42%. The independent risk factors were maternal (adjusted OR 1.8; 95% CI 1.1, 2.9) and paternal smoking (2.2; 1.3, 3.6), use of alcohol (2.2; 1.1, 4.4), placenta previa. (5.7; 1.4, 23.1), pre-eclampsia (2.7; 1.3, 5.6), and chorioamnionitis (3.3, 1.0, 10.0). Vaginal bleeding (70%), abdominal pain (51%), bloody amniotic fluid (50%), and fetal heart rate abnormalities (69%) were the most common manifestations. Neither bleeding nor pain was present in 19% of the cases. Overall, 59% had preterm labor (OR 12.9; 95% CI 8.3, 19.8), and 91% were delivered by cesarean section (34.7; 20.0, 60.1). Of the newborns, 25% were growth restricted. The perinatal mortality rate was 9.2% (OR 10.1; 95% CI 3.4, 30.1). Retroplacental blood clot was seen by ultrasound in 15% of the cases. Conclusions. Maternal alcohol consumption and smoking, and smoking by the partner turned out to be independent risk factors for placental abruption. Smoking by both partners multiplied the risk. The liberal use of ultrasound examination contributed little to the management of women with placental abruption."
    Original languageEnglish
    JournalActa Obstetricia et Gynecologica Scandinavica
    Volume85
    Issue number6
    Pages (from-to)700-705
    Number of pages6
    ISSN0001-6349
    DOIs
    Publication statusPublished - 2006
    MoE publication typeA1 Journal article-refereed

    Fields of Science

    • 312 Clinical medicine
    • Obstetrics and gynecology

    Cite this

    @article{a6c87fe335094104b4bf1e8c8b11ba04,
    title = "Clinical presentation and risk factors of placental abruption",
    abstract = "{"}Background. To study the risk factors of placental abruption during the index pregnancy. Methods. One hundred and ninety-eight women with placental abruption and 396 control women were identified among 46,742 women who delivered at a tertiary referral university hospital between 1997 and 2001. Clinical variables were compared between the groups. Multivariate logistic regression analysis was applied to identify independent risk factors. The clinical manifestations of placental abruption were also studied. Results. The overall incidence of placental abruption was 0.42{\%}. The independent risk factors were maternal (adjusted OR 1.8; 95{\%} CI 1.1, 2.9) and paternal smoking (2.2; 1.3, 3.6), use of alcohol (2.2; 1.1, 4.4), placenta previa. (5.7; 1.4, 23.1), pre-eclampsia (2.7; 1.3, 5.6), and chorioamnionitis (3.3, 1.0, 10.0). Vaginal bleeding (70{\%}), abdominal pain (51{\%}), bloody amniotic fluid (50{\%}), and fetal heart rate abnormalities (69{\%}) were the most common manifestations. Neither bleeding nor pain was present in 19{\%} of the cases. Overall, 59{\%} had preterm labor (OR 12.9; 95{\%} CI 8.3, 19.8), and 91{\%} were delivered by cesarean section (34.7; 20.0, 60.1). Of the newborns, 25{\%} were growth restricted. The perinatal mortality rate was 9.2{\%} (OR 10.1; 95{\%} CI 3.4, 30.1). Retroplacental blood clot was seen by ultrasound in 15{\%} of the cases. Conclusions. Maternal alcohol consumption and smoking, and smoking by the partner turned out to be independent risk factors for placental abruption. Smoking by both partners multiplied the risk. The liberal use of ultrasound examination contributed little to the management of women with placental abruption.{"}",
    keywords = "312 Clinical medicine, Obstetrics and gynecology",
    author = "Minna Tikkanen and Mika Nuutila and Vilho Hiilesmaa and Jorma Paavonen and Olavi Ylikorkala",
    year = "2006",
    doi = "10.1080/00016340500449915",
    language = "English",
    volume = "85",
    pages = "700--705",
    journal = "Acta Obstetricia et Gynecologica Scandinavica",
    issn = "0001-6349",
    publisher = "Wiley",
    number = "6",

    }

    TY - JOUR

    T1 - Clinical presentation and risk factors of placental abruption

    AU - Tikkanen, Minna

    AU - Nuutila, Mika

    AU - Hiilesmaa, Vilho

    AU - Paavonen, Jorma

    AU - Ylikorkala, Olavi

    PY - 2006

    Y1 - 2006

    N2 - "Background. To study the risk factors of placental abruption during the index pregnancy. Methods. One hundred and ninety-eight women with placental abruption and 396 control women were identified among 46,742 women who delivered at a tertiary referral university hospital between 1997 and 2001. Clinical variables were compared between the groups. Multivariate logistic regression analysis was applied to identify independent risk factors. The clinical manifestations of placental abruption were also studied. Results. The overall incidence of placental abruption was 0.42%. The independent risk factors were maternal (adjusted OR 1.8; 95% CI 1.1, 2.9) and paternal smoking (2.2; 1.3, 3.6), use of alcohol (2.2; 1.1, 4.4), placenta previa. (5.7; 1.4, 23.1), pre-eclampsia (2.7; 1.3, 5.6), and chorioamnionitis (3.3, 1.0, 10.0). Vaginal bleeding (70%), abdominal pain (51%), bloody amniotic fluid (50%), and fetal heart rate abnormalities (69%) were the most common manifestations. Neither bleeding nor pain was present in 19% of the cases. Overall, 59% had preterm labor (OR 12.9; 95% CI 8.3, 19.8), and 91% were delivered by cesarean section (34.7; 20.0, 60.1). Of the newborns, 25% were growth restricted. The perinatal mortality rate was 9.2% (OR 10.1; 95% CI 3.4, 30.1). Retroplacental blood clot was seen by ultrasound in 15% of the cases. Conclusions. Maternal alcohol consumption and smoking, and smoking by the partner turned out to be independent risk factors for placental abruption. Smoking by both partners multiplied the risk. The liberal use of ultrasound examination contributed little to the management of women with placental abruption."

    AB - "Background. To study the risk factors of placental abruption during the index pregnancy. Methods. One hundred and ninety-eight women with placental abruption and 396 control women were identified among 46,742 women who delivered at a tertiary referral university hospital between 1997 and 2001. Clinical variables were compared between the groups. Multivariate logistic regression analysis was applied to identify independent risk factors. The clinical manifestations of placental abruption were also studied. Results. The overall incidence of placental abruption was 0.42%. The independent risk factors were maternal (adjusted OR 1.8; 95% CI 1.1, 2.9) and paternal smoking (2.2; 1.3, 3.6), use of alcohol (2.2; 1.1, 4.4), placenta previa. (5.7; 1.4, 23.1), pre-eclampsia (2.7; 1.3, 5.6), and chorioamnionitis (3.3, 1.0, 10.0). Vaginal bleeding (70%), abdominal pain (51%), bloody amniotic fluid (50%), and fetal heart rate abnormalities (69%) were the most common manifestations. Neither bleeding nor pain was present in 19% of the cases. Overall, 59% had preterm labor (OR 12.9; 95% CI 8.3, 19.8), and 91% were delivered by cesarean section (34.7; 20.0, 60.1). Of the newborns, 25% were growth restricted. The perinatal mortality rate was 9.2% (OR 10.1; 95% CI 3.4, 30.1). Retroplacental blood clot was seen by ultrasound in 15% of the cases. Conclusions. Maternal alcohol consumption and smoking, and smoking by the partner turned out to be independent risk factors for placental abruption. Smoking by both partners multiplied the risk. The liberal use of ultrasound examination contributed little to the management of women with placental abruption."

    KW - 312 Clinical medicine

    KW - Obstetrics and gynecology

    U2 - 10.1080/00016340500449915

    DO - 10.1080/00016340500449915

    M3 - Article

    VL - 85

    SP - 700

    EP - 705

    JO - Acta Obstetricia et Gynecologica Scandinavica

    JF - Acta Obstetricia et Gynecologica Scandinavica

    SN - 0001-6349

    IS - 6

    ER -