Clinical Studies on Drug-Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalClinical Pharmacology and Therapeutics
Volume105
Issue number6
Pages (from-to)1345-1361
Number of pages17
ISSN0009-9236
DOIs
Publication statusPublished - Jun 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • TIME-DEPENDENT PHARMACOKINETICS
  • PLASMA-CONCENTRATIONS
  • ROSUVASTATIN PHARMACOKINETICS
  • INTERACTION ASSESSMENTS
  • ENDOGENOUS BIOMARKERS
  • MARKEDLY DECREASES
  • GRAPEFRUIT JUICE
  • GENEVA COCKTAIL
  • CYTOCHROME-P450
  • INHIBITION
  • 317 Pharmacy
  • 3111 Biomedicine

Cite this

@article{d752c5c832de4ed1b490271266873ce3,
title = "Clinical Studies on Drug-Drug Interactions Involving Metabolism and Transport: Methodology, Pitfalls, and Interpretation",
keywords = "TIME-DEPENDENT PHARMACOKINETICS, PLASMA-CONCENTRATIONS, ROSUVASTATIN PHARMACOKINETICS, INTERACTION ASSESSMENTS, ENDOGENOUS BIOMARKERS, MARKEDLY DECREASES, GRAPEFRUIT JUICE, GENEVA COCKTAIL, CYTOCHROME-P450, INHIBITION, 317 Pharmacy, 3111 Biomedicine",
author = "Aleksi Tornio and Filppula, {Anne M.} and Mikko Niemi and Backman, {Janne T.}",
year = "2019",
month = "6",
doi = "10.1002/cpt.1435",
language = "English",
volume = "105",
pages = "1345--1361",
journal = "Clinical Pharmacology and Therapeutics",
issn = "0009-9236",
publisher = "Wiley",
number = "6",

}

TY - JOUR

T1 - Clinical Studies on Drug-Drug Interactions Involving Metabolism and Transport

T2 - Methodology, Pitfalls, and Interpretation

AU - Tornio, Aleksi

AU - Filppula, Anne M.

AU - Niemi, Mikko

AU - Backman, Janne T.

PY - 2019/6

Y1 - 2019/6

KW - TIME-DEPENDENT PHARMACOKINETICS

KW - PLASMA-CONCENTRATIONS

KW - ROSUVASTATIN PHARMACOKINETICS

KW - INTERACTION ASSESSMENTS

KW - ENDOGENOUS BIOMARKERS

KW - MARKEDLY DECREASES

KW - GRAPEFRUIT JUICE

KW - GENEVA COCKTAIL

KW - CYTOCHROME-P450

KW - INHIBITION

KW - 317 Pharmacy

KW - 3111 Biomedicine

U2 - 10.1002/cpt.1435

DO - 10.1002/cpt.1435

M3 - Article

VL - 105

SP - 1345

EP - 1361

JO - Clinical Pharmacology and Therapeutics

JF - Clinical Pharmacology and Therapeutics

SN - 0009-9236

IS - 6

ER -