Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalClinical Pharmacology and Therapeutics
Volume105
Issue number1
Pages (from-to)219-228
Number of pages10
ISSN0009-9236
DOIs
Publication statusPublished - Jan 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • DRUG-DRUG INTERACTION
  • ACTING ANTIVIRAL REGIMEN
  • PLASMA-CONCENTRATIONS
  • MARKEDLY INCREASES
  • CYTOCHROME-P450 3A
  • PLUS DASABUVIR
  • PHARMACOKINETICS
  • OMBITASVIR
  • PARITAPREVIR/RITONAVIR
  • PHARMACODYNAMICS
  • 317 Pharmacy
  • 3111 Biomedicine

Cite this

@article{1d087619e813400a89e3e7e65d3bf39d,
title = "Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel",
keywords = "DRUG-DRUG INTERACTION, ACTING ANTIVIRAL REGIMEN, PLASMA-CONCENTRATIONS, MARKEDLY INCREASES, CYTOCHROME-P450 3A, PLUS DASABUVIR, PHARMACOKINETICS, OMBITASVIR, PARITAPREVIR/RITONAVIR, PHARMACODYNAMICS, 317 Pharmacy, 3111 Biomedicine",
author = "Itkonen, {Matti K.} and Aleksi Tornio and Outi Lapatto-Reiniluoto and Mikko Neuvonen and Neuvonen, {Pertti J.} and Mikko Niemi and Backman, {Janne T.}",
year = "2019",
month = "1",
doi = "10.1002/cpt.1099",
language = "English",
volume = "105",
pages = "219--228",
journal = "Clinical Pharmacology and Therapeutics",
issn = "0009-9236",
publisher = "Wiley",
number = "1",

}

TY - JOUR

T1 - Clopidogrel Increases Dasabuvir Exposure With or Without Ritonavir, and Ritonavir Inhibits the Bioactivation of Clopidogrel

AU - Itkonen, Matti K.

AU - Tornio, Aleksi

AU - Lapatto-Reiniluoto, Outi

AU - Neuvonen, Mikko

AU - Neuvonen, Pertti J.

AU - Niemi, Mikko

AU - Backman, Janne T.

PY - 2019/1

Y1 - 2019/1

KW - DRUG-DRUG INTERACTION

KW - ACTING ANTIVIRAL REGIMEN

KW - PLASMA-CONCENTRATIONS

KW - MARKEDLY INCREASES

KW - CYTOCHROME-P450 3A

KW - PLUS DASABUVIR

KW - PHARMACOKINETICS

KW - OMBITASVIR

KW - PARITAPREVIR/RITONAVIR

KW - PHARMACODYNAMICS

KW - 317 Pharmacy

KW - 3111 Biomedicine

U2 - 10.1002/cpt.1099

DO - 10.1002/cpt.1099

M3 - Article

VL - 105

SP - 219

EP - 228

JO - Clinical Pharmacology and Therapeutics

JF - Clinical Pharmacology and Therapeutics

SN - 0009-9236

IS - 1

ER -