Clopidogrel Markedly Increases Plasma Concentrations of CYP2C8 Substrate Pioglitazone

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDrug Metabolism and Disposition
Volume44
Issue number8
Pages (from-to)1364-1371
Number of pages8
ISSN0090-9556
DOIs
Publication statusPublished - Aug 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • DRUG-DRUG INTERACTIONS
  • TRANSPORTING POLYPEPTIDE 1B1
  • TYPE-2 DIABETES-MELLITUS
  • IN-VITRO
  • SLCO1B1 POLYMORPHISM
  • CYTOCHROME-P450 3A4
  • DEPENDENT INHIBITOR
  • SIMVASTATIN ACID
  • PHARMACOKINETICS
  • CERIVASTATIN
  • 3111 Biomedicine

Cite this

@article{6b5fe26f8a2b4e8db6e94077acbe65de,
title = "Clopidogrel Markedly Increases Plasma Concentrations of CYP2C8 Substrate Pioglitazone",
keywords = "DRUG-DRUG INTERACTIONS, TRANSPORTING POLYPEPTIDE 1B1, TYPE-2 DIABETES-MELLITUS, IN-VITRO, SLCO1B1 POLYMORPHISM, CYTOCHROME-P450 3A4, DEPENDENT INHIBITOR, SIMVASTATIN ACID, PHARMACOKINETICS, CERIVASTATIN, 3111 Biomedicine",
author = "Itkonen, {Matti K.} and Aleksi Tornio and Mikko Neuvonen and Neuvonen, {Pertti J.} and Mikko Niemi and Backman, {Janne T.}",
year = "2016",
month = "8",
doi = "10.1124/dmd.116.070375",
language = "English",
volume = "44",
pages = "1364--1371",
journal = "Drug Metabolism and Disposition",
issn = "1521-009X",
publisher = "American Society for Pharmacology and Experimental Therapeutics",
number = "8",

}

Clopidogrel Markedly Increases Plasma Concentrations of CYP2C8 Substrate Pioglitazone. / Itkonen, Matti K.; Tornio, Aleksi; Neuvonen, Mikko; Neuvonen, Pertti J.; Niemi, Mikko; Backman, Janne T.

In: Drug Metabolism and Disposition, Vol. 44, No. 8, 08.2016, p. 1364-1371.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Clopidogrel Markedly Increases Plasma Concentrations of CYP2C8 Substrate Pioglitazone

AU - Itkonen, Matti K.

AU - Tornio, Aleksi

AU - Neuvonen, Mikko

AU - Neuvonen, Pertti J.

AU - Niemi, Mikko

AU - Backman, Janne T.

PY - 2016/8

Y1 - 2016/8

KW - DRUG-DRUG INTERACTIONS

KW - TRANSPORTING POLYPEPTIDE 1B1

KW - TYPE-2 DIABETES-MELLITUS

KW - IN-VITRO

KW - SLCO1B1 POLYMORPHISM

KW - CYTOCHROME-P450 3A4

KW - DEPENDENT INHIBITOR

KW - SIMVASTATIN ACID

KW - PHARMACOKINETICS

KW - CERIVASTATIN

KW - 3111 Biomedicine

U2 - 10.1124/dmd.116.070375

DO - 10.1124/dmd.116.070375

M3 - Article

VL - 44

SP - 1364

EP - 1371

JO - Drug Metabolism and Disposition

JF - Drug Metabolism and Disposition

SN - 1521-009X

IS - 8

ER -