Clustering of Alpers disease mutations and catalytic defects in biochemical variants reveal new features of molecular mechanism of hte human mitochondrial replicase, Pol gamma

Liliya Euro, Gregory A. Farnum, Eino Palin, Anu Suomalainen, Laurie S. Kaguni

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalNucleic Acids Research
Volume39
Issue number21
Pages (from-to)9072-9084
Number of pages13
ISSN0305-1048
DOIs
Publication statusPublished - 2011
MoE publication typeA1 Journal article-refereed

Fields of Science

  • DNA-POLYMERASE-GAMMA
  • PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA
  • VIRION RNA-POLYMERASE
  • ACCESSORY SUBUNIT
  • STRUCTURAL BASIS
  • SACCHAROMYCES-CEREVISIAE
  • MULTIPLE DELETIONS
  • CRYSTAL-STRUCTURE
  • ESCHERICHIA-COLI
  • W748S MUTATION
  • 3124 Neurology and psychiatry

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