Cognitive Performance among Cognitively Healthy Adults Aged 30–100 Years

Minna Alenius, Sanna Koskinen, Ilona Hallikainen, Tiia Ngandu, Jari Lipsanen, Päivi Sainio, Annamari Tuulio-Henriksson, Tuomo Hänninen

Research output: Contribution to journalArticleScientificpeer-review

Abstract

Background/Aims: To detect cognitive decline in older adults, measures of verbal fluency and verbal memory are widely used. Less is known about performance in these measures in younger persons or according to education level and gender. We investigated cognitive performance according to age, education and gender among cognitively healthy adults aged 30-100 years. Methods: The study population comprised 4,174 cognitively healthy persons participating in the nationally representative Finnish Health 2011 survey. Cognitive assessment included verbal fluency, word list memory, word list recall and word list savings from the Consortium to Establish a Registry for Alzheimer's Disease neuropsychological battery. Results: Total variance in the cognitive test performance explained by age, education and gender varied from 12.3 to 31.2%. A decreasing trend in cognitive performance existed in all subtests by advancing age, with differences appearing between 50 and 55 years. Persons with the highest-education level performed best for all measures. For the participants <55 years, education explained part of the variance, while age and gender did not. Conclusions: When assessing cognition, age and education should be accounted for in more detail in research and clinical practice. Additionally, the cohort effect and its potential impact on the renewal cycle of future normative values for cognitive tests should be considered. (C) 2019 The Author(s) Published by S. Karger AG, Basel

Original languageEnglish
JournalDementia and geriatric cognitive disorders. Extra
Volume9
Issue number1
Pages (from-to)11-23
Number of pages13
ISSN1664-5464
DOIs
Publication statusPublished - 1 Feb 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 515 Psychology
  • Consortium to Establish a Registry for Alzheimer's Disease
  • Cognitive abilities screening instrument
  • Cognitive ageing
  • Education
  • VERBAL FLUENCY TESTS
  • ALZHEIMERS-DISEASE
  • NORMATIVE DATA
  • IMPAIRMENT
  • POPULATION
  • DEMENTIA
  • DECLINE
  • CERAD
  • CONSORTIUM
  • EDUCATION
  • 6162 Cognitive science

Cite this

Alenius, Minna ; Koskinen, Sanna ; Hallikainen, Ilona ; Ngandu, Tiia ; Lipsanen, Jari ; Sainio, Päivi ; Tuulio-Henriksson, Annamari ; Hänninen, Tuomo. / Cognitive Performance among Cognitively Healthy Adults Aged 30–100 Years. In: Dementia and geriatric cognitive disorders. Extra. 2019 ; Vol. 9, No. 1. pp. 11-23.
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abstract = "Background/Aims: To detect cognitive decline in older adults, measures of verbal fluency and verbal memory are widely used. Less is known about performance in these measures in younger persons or according to education level and gender. We investigated cognitive performance according to age, education and gender among cognitively healthy adults aged 30-100 years. Methods: The study population comprised 4,174 cognitively healthy persons participating in the nationally representative Finnish Health 2011 survey. Cognitive assessment included verbal fluency, word list memory, word list recall and word list savings from the Consortium to Establish a Registry for Alzheimer's Disease neuropsychological battery. Results: Total variance in the cognitive test performance explained by age, education and gender varied from 12.3 to 31.2{\%}. A decreasing trend in cognitive performance existed in all subtests by advancing age, with differences appearing between 50 and 55 years. Persons with the highest-education level performed best for all measures. For the participants <55 years, education explained part of the variance, while age and gender did not. Conclusions: When assessing cognition, age and education should be accounted for in more detail in research and clinical practice. Additionally, the cohort effect and its potential impact on the renewal cycle of future normative values for cognitive tests should be considered. (C) 2019 The Author(s) Published by S. Karger AG, Basel",
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Cognitive Performance among Cognitively Healthy Adults Aged 30–100 Years. / Alenius, Minna; Koskinen, Sanna; Hallikainen, Ilona; Ngandu, Tiia; Lipsanen, Jari; Sainio, Päivi; Tuulio-Henriksson, Annamari; Hänninen, Tuomo.

In: Dementia and geriatric cognitive disorders. Extra, Vol. 9, No. 1, 01.02.2019, p. 11-23.

Research output: Contribution to journalArticleScientificpeer-review

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AU - Alenius, Minna

AU - Koskinen, Sanna

AU - Hallikainen, Ilona

AU - Ngandu, Tiia

AU - Lipsanen, Jari

AU - Sainio, Päivi

AU - Tuulio-Henriksson, Annamari

AU - Hänninen, Tuomo

PY - 2019/2/1

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N2 - Background/Aims: To detect cognitive decline in older adults, measures of verbal fluency and verbal memory are widely used. Less is known about performance in these measures in younger persons or according to education level and gender. We investigated cognitive performance according to age, education and gender among cognitively healthy adults aged 30-100 years. Methods: The study population comprised 4,174 cognitively healthy persons participating in the nationally representative Finnish Health 2011 survey. Cognitive assessment included verbal fluency, word list memory, word list recall and word list savings from the Consortium to Establish a Registry for Alzheimer's Disease neuropsychological battery. Results: Total variance in the cognitive test performance explained by age, education and gender varied from 12.3 to 31.2%. A decreasing trend in cognitive performance existed in all subtests by advancing age, with differences appearing between 50 and 55 years. Persons with the highest-education level performed best for all measures. For the participants <55 years, education explained part of the variance, while age and gender did not. Conclusions: When assessing cognition, age and education should be accounted for in more detail in research and clinical practice. Additionally, the cohort effect and its potential impact on the renewal cycle of future normative values for cognitive tests should be considered. (C) 2019 The Author(s) Published by S. Karger AG, Basel

AB - Background/Aims: To detect cognitive decline in older adults, measures of verbal fluency and verbal memory are widely used. Less is known about performance in these measures in younger persons or according to education level and gender. We investigated cognitive performance according to age, education and gender among cognitively healthy adults aged 30-100 years. Methods: The study population comprised 4,174 cognitively healthy persons participating in the nationally representative Finnish Health 2011 survey. Cognitive assessment included verbal fluency, word list memory, word list recall and word list savings from the Consortium to Establish a Registry for Alzheimer's Disease neuropsychological battery. Results: Total variance in the cognitive test performance explained by age, education and gender varied from 12.3 to 31.2%. A decreasing trend in cognitive performance existed in all subtests by advancing age, with differences appearing between 50 and 55 years. Persons with the highest-education level performed best for all measures. For the participants <55 years, education explained part of the variance, while age and gender did not. Conclusions: When assessing cognition, age and education should be accounted for in more detail in research and clinical practice. Additionally, the cohort effect and its potential impact on the renewal cycle of future normative values for cognitive tests should be considered. (C) 2019 The Author(s) Published by S. Karger AG, Basel

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KW - ALZHEIMERS-DISEASE

KW - NORMATIVE DATA

KW - IMPAIRMENT

KW - POPULATION

KW - DEMENTIA

KW - DECLINE

KW - CERAD

KW - CONSORTIUM

KW - EDUCATION

KW - 6162 Cognitive science

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DO - 10.1159/000495657

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JO - Dementia and geriatric cognitive disorders. Extra

JF - Dementia and geriatric cognitive disorders. Extra

SN - 1664-5464

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