Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine

Jonna Jalanka; Ching Lam; Andrew Bennett; Anna Hartikainen; Fiona Crispie; Laura A. Finnegan; Paul D. Cotter; Robin Spiller

doi:10.5056/jnm20205

Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine

Jonna Jalanka, Ching Lam, Andrew Bennett, Anna Hartikainen, Fiona Crispie, Laura A. Finnegan, Paul D. Cotter, Robin Spiller

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of neurogastroenterology and motility
Volume	27
Issue number	2
Pages (from-to)	279-291
Number of pages	13
ISSN	2093-0879
DOIs	https://doi.org/10.5056/jnm20205
Publication status	Published - Apr 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

Gene expression
Irritable bowel syndrome
Mesalazine
Microbiota
Toll-like receptor 4
5-AMINOSALICYLIC ACID
GASTROINTESTINAL MOTILITY
PROTEASE ACTIVITY
GUT MICROBIOTA
IBS
PERMEABILITY
ACTIVATION
BRADYKININ
BACTERIAL
SEVERITY
3121 General medicine, internal medicine and other clinical medicine
3112 Neurosciences
3124 Neurology and psychiatry

Access to Document

10.5056/jnm20205

jnm-27-2-279Final published version, 417 KBLicence: CC BY-NC

Cite this

Jalanka, J., Lam, C., Bennett, A., Hartikainen, A., Crispie, F., Finnegan, L. A., Cotter, P. D., & Spiller, R. (2021). Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine. Journal of neurogastroenterology and motility, 27(2), 279-291. https://doi.org/10.5056/jnm20205

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title = "Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine",

keywords = "Gene expression, Irritable bowel syndrome, Mesalazine, Microbiota, Toll-like receptor 4, 5-AMINOSALICYLIC ACID, GASTROINTESTINAL MOTILITY, PROTEASE ACTIVITY, GUT MICROBIOTA, IBS, PERMEABILITY, ACTIVATION, BRADYKININ, BACTERIAL, SEVERITY, 3121 General medicine, internal medicine and other clinical medicine, 3112 Neurosciences, 3124 Neurology and psychiatry",

author = "Jonna Jalanka and Ching Lam and Andrew Bennett and Anna Hartikainen and Fiona Crispie and Finnegan, {Laura A.} and Cotter, {Paul D.} and Robin Spiller",

year = "2021",

month = apr,

doi = "10.5056/jnm20205",

language = "English",

volume = "27",

pages = "279--291",

journal = "Journal of neurogastroenterology and motility",

issn = "2093-0879",

publisher = "Korean Society of Neurogastroenterology and Motility ",

number = "2",

}

Jalanka, J, Lam, C, Bennett, A, Hartikainen, A, Crispie, F, Finnegan, LA, Cotter, PD & Spiller, R 2021, 'Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine', Journal of neurogastroenterology and motility, vol. 27, no. 2, pp. 279-291. https://doi.org/10.5056/jnm20205

Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome: Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine. / Jalanka, Jonna; Lam, Ching; Bennett, Andrew et al.
In: Journal of neurogastroenterology and motility, Vol. 27, No. 2, 04.2021, p. 279-291.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Colonic Gene Expression and Fecal Microbiota in Diarrhea-predominant Irritable Bowel Syndrome

T2 - Increased Toll-like Receptor 4 but Minimal Inflammation and no Response to Mesalazine

AU - Jalanka, Jonna

AU - Lam, Ching

AU - Bennett, Andrew

AU - Hartikainen, Anna

AU - Crispie, Fiona

AU - Finnegan, Laura A.

AU - Cotter, Paul D.

AU - Spiller, Robin

PY - 2021/4

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KW - Irritable bowel syndrome

KW - Mesalazine

KW - Microbiota

KW - Toll-like receptor 4

KW - 5-AMINOSALICYLIC ACID

KW - GASTROINTESTINAL MOTILITY

KW - PROTEASE ACTIVITY

KW - GUT MICROBIOTA

KW - IBS

KW - PERMEABILITY

KW - ACTIVATION

KW - BRADYKININ

KW - BACTERIAL

KW - SEVERITY

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 3112 Neurosciences

KW - 3124 Neurology and psychiatry

U2 - 10.5056/jnm20205

DO - 10.5056/jnm20205

M3 - Article

SN - 2093-0879

VL - 27

SP - 279

EP - 291

JO - Journal of neurogastroenterology and motility

JF - Journal of neurogastroenterology and motility

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