Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease

Antti Huotarinen; Anna-Maija Penttinen; Susanne Bäck; Merja H. Voutilainen; Ulrika Julku; T. Petteri Piepponen; Pekka T. Männistö; Mart Saarma; Raimo Tuominen; Aki Laakso; Mikko Airavaara

doi:10.1016/j.neuroscience.2018.01.052

Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease

Antti Huotarinen, Anna-Maija Penttinen, Susanne Bäck, Merja H. Voutilainen, Ulrika Julku, T. Petteri Piepponen, Pekka T. Männistö, Mart Saarma, Raimo Tuominen, Aki Laakso, Mikko Airavaara

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Neuroscience
Volume	374
Pages (from-to)	250-263
Number of pages	14
ISSN	0306-4522
DOIs	https://doi.org/10.1016/j.neuroscience.2018.01.052
Publication status	Published - 15 Mar 2018
MoE publication type	A1 Journal article-refereed

Fields of Science

CDNF
MANF
GDNF
neurotrophic factor
median forebrain bundle
6-hydroxydopamine
STN DBS
HIGH-FREQUENCY STIMULATION
SUBTHALAMIC NUCLEUS STIMULATION
NIGROSTRIATAL DOPAMINE SYSTEM
6-HYDROXYDOPAMINE LESIONED RATS
NEURONS IN-VIVO
NEUROTROPHIC FACTOR
GENE-THERAPY
STRIATAL DOPAMINE
MICE
3112 Neurosciences

Access to Document

10.1016/j.neuroscience.2018.01.052

1-s2.0-S0306452218300824-mainFinal published version, 2.2 MBLicence: CC BY-NC-ND

Cite this

Huotarinen, A., Penttinen, A.-M., Bäck, S., Voutilainen, M. H., Julku, U., Piepponen, T. P., Männistö, P. T., Saarma, M., Tuominen, R., Laakso, A., & Airavaara, M. (2018). Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease. Neuroscience, 374, 250-263. https://doi.org/10.1016/j.neuroscience.2018.01.052

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title = "Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease",

keywords = "CDNF, MANF, GDNF, neurotrophic factor, median forebrain bundle, 6-hydroxydopamine, STN DBS, HIGH-FREQUENCY STIMULATION, SUBTHALAMIC NUCLEUS STIMULATION, NIGROSTRIATAL DOPAMINE SYSTEM, 6-HYDROXYDOPAMINE LESIONED RATS, NEURONS IN-VIVO, NEUROTROPHIC FACTOR, GENE-THERAPY, STRIATAL DOPAMINE, MICE, 3112 Neurosciences",

author = "Antti Huotarinen and Anna-Maija Penttinen and Susanne B{\"a}ck and Voutilainen, {Merja H.} and Ulrika Julku and Piepponen, {T. Petteri} and M{\"a}nnist{\"o}, {Pekka T.} and Mart Saarma and Raimo Tuominen and Aki Laakso and Mikko Airavaara",

year = "2018",

month = mar,

day = "15",

doi = "10.1016/j.neuroscience.2018.01.052",

language = "English",

volume = "374",

pages = "250--263",

journal = "Neuroscience",

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TY - JOUR

T1 - Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease

AU - Huotarinen, Antti

AU - Penttinen, Anna-Maija

AU - Bäck, Susanne

AU - Voutilainen, Merja H.

AU - Julku, Ulrika

AU - Piepponen, T. Petteri

AU - Männistö, Pekka T.

AU - Saarma, Mart

AU - Tuominen, Raimo

AU - Laakso, Aki

AU - Airavaara, Mikko

PY - 2018/3/15

Y1 - 2018/3/15

KW - CDNF

KW - MANF

KW - GDNF

KW - neurotrophic factor

KW - median forebrain bundle

KW - 6-hydroxydopamine

KW - STN DBS

KW - HIGH-FREQUENCY STIMULATION

KW - SUBTHALAMIC NUCLEUS STIMULATION

KW - NIGROSTRIATAL DOPAMINE SYSTEM

KW - 6-HYDROXYDOPAMINE LESIONED RATS

KW - NEURONS IN-VIVO

KW - NEUROTROPHIC FACTOR

KW - GENE-THERAPY

KW - STRIATAL DOPAMINE

KW - MICE

KW - 3112 Neurosciences

U2 - 10.1016/j.neuroscience.2018.01.052

DO - 10.1016/j.neuroscience.2018.01.052

M3 - Article

SN - 0306-4522

VL - 374

SP - 250

EP - 263

JO - Neuroscience

JF - Neuroscience

ER -