Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Michael P. Menden; Dennis Wang; Mike J. Mason; Bence Szalai; Krishna C. Bulusu; Yuanfang Guan; Thomas Yu; Jaewoo Kang; Minji Jeon; Russ Wolfinger; Tin Nguyen; Mikhail Zaslavskiy; Jordi Abante; Barbara Schmitz Abecassis; Nanne Aben; Delasa Aghamirzaie; Tero Aittokallio; Farida S. Akhtari; Bissan Al-lazikani; Tanvir Alam; Amin Allam; Chad Allen; Mariana Pelicano de Almeida; Doaa Altarawy; Vinicius Alves; Alicia Amadoz; Benedict Anchang; Albert A. Antolin; Jeremy R. Ash; Victoria Romeo Aznar; Wail Ba-alawi; Moeen Bagheri; Vladimir Bajic; Gordon Ball; Pedro J. Ballester; Delora Baptista; Christopher Bare; Mathilde Bateson; Andreas Bender; Denis Bertrand; Bhagya Wijayawardena; Keith A. Boroevich; Evert Bosdriesz; Salim Bougouffa; Gergana Bounova; Thomas Brouwer; Barbara Bryant; Manuel Calaza; Alberto Calderone; Stefano Calza; Stephen Capuzzi; Jose Carbonell-Caballero; Daniel Carlin; Hannah Carter; Luisa Castagnoli; Remzi Celebi; Gianni Cesareni; Hyeokyoon Chang; Guocai Chen; Haoran Chen; Huiyuan Chen; Lijun Cheng; Ariel Chernomoretz; Davide Chicco; Kwang-Hyun Cho; Sunghwan Cho; Daeseon Choi; Jaejoon Choi; Kwanghun Choi; Minsoo Choi; Martine De Cock; Elizabeth Coker; Isidro Cortes-Ciriano; Miklós Cserzö; Cankut Cubuk; Christina Curtis; Dries Van Daele; Cuong C. Dang; Tjeerd Dijkstra; Joaquin Dopazo; Sorin Draghici; Anastasios Drosou; Michel Dumontier; Friederike Ehrhart; Fatma-Elzahraa Eid; Mahmoud ElHefnawi; Haitham Elmarakeby; Bo van Engelen; Hatice Billur Engin; Iwan de Esch; Chris Evelo; Andre O. Falcao; Sherif Farag; Carlos Fernandez-Lozano; Kathleen Fisch; Asmund Flobak; Chiara Fornari; Amir B. K. Foroushani; Donatien Chedom Fotso; Denis Fourches; Stephen Friend; Arnoldo Frigessi; Feng Gao; Xiaoting Gao; Jeffrey M. Gerold; Pierre Gestraud; Samik Ghosh; Jussi Gillberg; Antonia Godoy-Lorite; Lizzy Godynyuk; Adam Godzik; Anna Goldenberg; David Gomez-Cabrero; Mehmet Gonen; Chris de Graaf; Harry Gray; Maxim Grechkin; Roger Guimera; Emre Guney; Benjamin Haibe-Kains; Younghyun Han; Takeshi Hase; Di He; Liye He; Lenwood S. Heath; Kristoffer H. Hellton; Manuela Helmer-Citterich; Marta R. Hidalgo; Daniel Hidru; Steven M. Hill; Sepp Hochreiter; Seungpyo Hong; Eivind Hovig; Ya-Chih Hsueh; Zhiyuan Hu; Justin K. Huang; R. Stephanie Huang; László Hunyady; Jinseub Hwang; Tae Hyun Hwang; Woochang Hwang; Yongdeuk Hwang; Olexandr Isayev; Oliver Bear Don’t Walk; John Jack; Samad Jahandideh; Jiadong Ji; Yousang Jo; Piotr J. Kamola; Georgi K. Kanev; Loukia Karacosta; Mostafa Karimi; Samuel Kaski; Marat Kazanov; Abdullah M. Khamis; Suleiman Ali Khan; Narsis A. Kiani; Allen Kim; Jinhan Kim; Juntae Kim; Kiseong Kim; Kyung Kim; Sunkyu Kim; Yongsoo Kim; Yunseong Kim; Paul D. W. Kirk; Hiroaki Kitano; Gunter Klambauer; David Knowles; Melissa Ko; Alvaro Kohn-Luque; Albert J. Kooistra; Melaine A. Kuenemann; Martin Kuiper; Christoph Kurz; Mijin Kwon; Twan van Laarhoven; Astrid Laegreid; Simone Lederer; Heewon Lee; Jeon Lee; Yun Woo Lee; Eemeli Lepp_aho; Richard Lewis; Jing Li; Lang Li; James Liley; Weng Khong Lim; Chieh Lin; Yiyi Liu; Yosvany Lopez; Joshua Low; Artem Lysenko; Daniel Machado; Neel Madhukar; Dries De Maeyer; Ana Belen Malpartida; Hiroshi Mamitsuka; Francesco Marabita; Kathleen Marchal; Pekka Marttinen; Daniel Mason; Alireza Mazaheri; Arfa Mehmood; Ali Mehreen; Magali Michaut; Ryan A. Miller; Costas Mitsopoulos; Dezso Modos; Marijke Van Moerbeke; Keagan Moo; Alison Motsinger-Reif; Rajiv Movva; Sebastian Muraru; Eugene Muratov; Mushthofa Mushthofa; Niranjan Nagarajan; Sigve Nakken; Aritro Nath; Pierre Neuvial; Richard Newton; Zheng Ning; Carlos De Niz; Baldo Oliva; Catharina Olsen; Antonio Palmeri; Bhawan Panesar; Stavros Papadopoulos; Jaesub Park; Seonyeong Park; Sungjoon Park; Yudi Pawitan; Daniele Peluso; Sriram Pendyala; Jian Peng; Livia Perfetto; Stefano Pirro; Sylvia Plevritis; Regina Politi; Hoifung Poon; Eduard Porta; Isak Prellner; Kristina Preuer; Miguel Angel Pujana; Ricardo Ramnarine; John E. Reid; Fabien Reyal; Sylvia Richardson; Camir Ricketts; Linda Rieswijk; Miguel Rocha; Carmen Rodriguez-Gonzalvez; Kyle Roell; Daniel Rotroff; Julian R. de Ruiter; Ploy Rukawa; Benjamin Sadacca; Zhaleh Safikhani; Fita Safitri; Marta Sales-Pardo; Sebastian Sauer; Moritz Schlichting; Jose A. Seoane; Jordi Serra; Ming-Mei Shang; Alok Sharma; Hari Sharma; Yang Shen; Motoki Shiga; Moonshik Shin; Ziv Shkedy; Kevin Shopsowitz; Sam Sinai; Dylan Skola; Petr Smirnov; Izel Fourie Soerensen; Peter Soerensen; Je-Hoon Song; Sang Ok Song; Othman Soufan; Andreas Spitzmueller; Boris Steipe; Chayaporn Suphavilai; Sergio Pulido Tamayo; David Tamborero; Jing Tang; Zia-ur-Rehman Tanoli; Marc Tarres-Deulofeu; Jesper Tegner; Liv Thommesen; Seyed Ali Madani Tonekaboni; Hong Tran; Ewoud De Troyer; Amy Truong; Tatsuhiko Tsunoda; Gábor Turu; Guang-Yo Tzeng; Lieven Verbeke; Santiago Videla; AstraZeneca-Sanger Drug Combination DREAM Consortium

doi:10.1038/s41467-019-09799-2

Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Michael P. Menden, Dennis Wang, Mike J. Mason, Bence Szalai, Krishna C. Bulusu, Yuanfang Guan, Thomas Yu, Jaewoo Kang, Minji Jeon, Russ Wolfinger, Tin Nguyen, Mikhail Zaslavskiy, Jordi Abante, Barbara Schmitz Abecassis, Nanne Aben, Delasa Aghamirzaie, Tero Aittokallio, Farida S. Akhtari, Bissan Al-lazikani, Tanvir AlamAmin Allam, Chad Allen, Mariana Pelicano de Almeida, Doaa Altarawy, Vinicius Alves, Alicia Amadoz, Benedict Anchang, Albert A. Antolin, Jeremy R. Ash, Victoria Romeo Aznar, Wail Ba-alawi, Moeen Bagheri, Vladimir Bajic, Gordon Ball, Pedro J. Ballester, Delora Baptista, Christopher Bare, Mathilde Bateson, Andreas Bender, Denis Bertrand, Bhagya Wijayawardena, Keith A. Boroevich, Evert Bosdriesz, Salim Bougouffa, Gergana Bounova, Thomas Brouwer, Barbara Bryant, Manuel Calaza, Alberto Calderone, Stefano Calza, Stephen Capuzzi, Jose Carbonell-Caballero, Daniel Carlin, Hannah Carter, Luisa Castagnoli, Remzi Celebi, Gianni Cesareni, Hyeokyoon Chang, Guocai Chen, Haoran Chen, Huiyuan Chen, Lijun Cheng, Ariel Chernomoretz, Davide Chicco, Kwang-Hyun Cho, Sunghwan Cho, Daeseon Choi, Jaejoon Choi, Kwanghun Choi, Minsoo Choi, Martine De Cock, Elizabeth Coker, Isidro Cortes-Ciriano, Miklós Cserzö, Cankut Cubuk, Christina Curtis, Dries Van Daele, Cuong C. Dang, Tjeerd Dijkstra, Joaquin Dopazo, Sorin Draghici, Anastasios Drosou, Michel Dumontier, Friederike Ehrhart, Fatma-Elzahraa Eid, Mahmoud ElHefnawi, Haitham Elmarakeby, Bo van Engelen, Hatice Billur Engin, Iwan de Esch, Chris Evelo, Andre O. Falcao, Sherif Farag, Carlos Fernandez-Lozano, Kathleen Fisch, Asmund Flobak, Chiara Fornari, Amir B. K. Foroushani, Donatien Chedom Fotso, Denis Fourches, Stephen Friend, Arnoldo Frigessi, Feng Gao, Xiaoting Gao, Jeffrey M. Gerold, Pierre Gestraud, Samik Ghosh, Jussi Gillberg, Antonia Godoy-Lorite, Lizzy Godynyuk, Adam Godzik, Anna Goldenberg, David Gomez-Cabrero, Mehmet Gonen, Chris de Graaf, Harry Gray, Maxim Grechkin, Roger Guimera, Emre Guney, Benjamin Haibe-Kains, Younghyun Han, Takeshi Hase, Di He, Liye He, Lenwood S. Heath, Kristoffer H. Hellton, Manuela Helmer-Citterich, Marta R. Hidalgo, Daniel Hidru, Steven M. Hill, Sepp Hochreiter, Seungpyo Hong, Eivind Hovig, Ya-Chih Hsueh, Zhiyuan Hu, Justin K. Huang, R. Stephanie Huang, László Hunyady, Jinseub Hwang, Tae Hyun Hwang, Woochang Hwang, Yongdeuk Hwang, Olexandr Isayev, Oliver Bear Don’t Walk, John Jack, Samad Jahandideh, Jiadong Ji, Yousang Jo, Piotr J. Kamola, Georgi K. Kanev, Loukia Karacosta, Mostafa Karimi, Samuel Kaski, Marat Kazanov, Abdullah M. Khamis, Suleiman Ali Khan, Narsis A. Kiani, Allen Kim, Jinhan Kim, Juntae Kim, Kiseong Kim, Kyung Kim, Sunkyu Kim, Yongsoo Kim, Yunseong Kim, Paul D. W. Kirk, Hiroaki Kitano, Gunter Klambauer, David Knowles, Melissa Ko, Alvaro Kohn-Luque, Albert J. Kooistra, Melaine A. Kuenemann, Martin Kuiper, Christoph Kurz, Mijin Kwon, Twan van Laarhoven, Astrid Laegreid, Simone Lederer, Heewon Lee, Jeon Lee, Yun Woo Lee, Eemeli Lepp_aho, Richard Lewis, Jing Li, Lang Li, James Liley, Weng Khong Lim, Chieh Lin, Yiyi Liu, Yosvany Lopez, Joshua Low, Artem Lysenko, Daniel Machado, Neel Madhukar, Dries De Maeyer, Ana Belen Malpartida, Hiroshi Mamitsuka, Francesco Marabita, Kathleen Marchal, Pekka Marttinen, Daniel Mason, Alireza Mazaheri, Arfa Mehmood, Ali Mehreen, Magali Michaut, Ryan A. Miller, Costas Mitsopoulos, Dezso Modos, Marijke Van Moerbeke, Keagan Moo, Alison Motsinger-Reif, Rajiv Movva, Sebastian Muraru, Eugene Muratov, Mushthofa Mushthofa, Niranjan Nagarajan, Sigve Nakken, Aritro Nath, Pierre Neuvial, Richard Newton, Zheng Ning, Carlos De Niz, Baldo Oliva, Catharina Olsen, Antonio Palmeri, Bhawan Panesar, Stavros Papadopoulos, Jaesub Park, Seonyeong Park, Sungjoon Park, Yudi Pawitan, Daniele Peluso, Sriram Pendyala, Jian Peng, Livia Perfetto, Stefano Pirro, Sylvia Plevritis, Regina Politi, Hoifung Poon, Eduard Porta, Isak Prellner, Kristina Preuer, Miguel Angel Pujana, Ricardo Ramnarine, John E. Reid, Fabien Reyal, Sylvia Richardson, Camir Ricketts, Linda Rieswijk, Miguel Rocha, Carmen Rodriguez-Gonzalvez, Kyle Roell, Daniel Rotroff, Julian R. de Ruiter, Ploy Rukawa, Benjamin Sadacca, Zhaleh Safikhani, Fita Safitri, Marta Sales-Pardo, Sebastian Sauer, Moritz Schlichting, Jose A. Seoane, Jordi Serra, Ming-Mei Shang, Alok Sharma, Hari Sharma, Yang Shen, Motoki Shiga, Moonshik Shin, Ziv Shkedy, Kevin Shopsowitz, Sam Sinai, Dylan Skola, Petr Smirnov, Izel Fourie Soerensen, Peter Soerensen, Je-Hoon Song, Sang Ok Song, Othman Soufan, Andreas Spitzmueller, Boris Steipe, Chayaporn Suphavilai, Sergio Pulido Tamayo, David Tamborero, Jing Tang, Zia-ur-Rehman Tanoli, Marc Tarres-Deulofeu, Jesper Tegner, Liv Thommesen, Seyed Ali Madani Tonekaboni, Hong Tran, Ewoud De Troyer, Amy Truong, Tatsuhiko Tsunoda, Gábor Turu, Guang-Yo Tzeng, Lieven Verbeke, Santiago Videla, AstraZeneca-Sanger Drug Combination DREAM Consortium

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	2674
Journal	Nature Communications
Volume	10
Issue number	1
Number of pages	17
ISSN	2041-1723
DOIs	https://doi.org/10.1038/s41467-019-09799-2
Publication status	Published - 17 Jun 2019
MoE publication type	A1 Journal article-refereed

Fields of Science

ANDROGEN RECEPTOR
BREAST-CANCER
CELL
GENE
INHIBITION
LANDSCAPE
MUTATIONS
PATHWAY
RESISTANCE
RESOURCE
317 Pharmacy
3122 Cancers

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s41467-019-09799-2Final published version, 1.57 MBLicence: CC BY

Cite this

Menden, M. P., Wang, D., Mason, M. J., Szalai, B., Bulusu, K. C., Guan, Y., Yu, T., Kang, J., Jeon, M., Wolfinger, R., Nguyen, T., Zaslavskiy, M., Abante, J., Abecassis, B. S., Aben, N., Aghamirzaie, D., Aittokallio, T., Akhtari, F. S., Al-lazikani, B., ... Consortium, A.-S. D. C. DREAM. (2019). Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen. Nature Communications, 10(1), Article 2674. https://doi.org/10.1038/s41467-019-09799-2

@article{10779a778b764133bda813f9373c833c,

title = "Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen",

keywords = "ANDROGEN RECEPTOR, BREAST-CANCER, CELL, GENE, INHIBITION, LANDSCAPE, MUTATIONS, PATHWAY, RESISTANCE, RESOURCE, 317 Pharmacy, 3122 Cancers",

author = "Menden, {Michael P.} and Dennis Wang and Mason, {Mike J.} and Bence Szalai and Bulusu, {Krishna C.} and Yuanfang Guan and Thomas Yu and Jaewoo Kang and Minji Jeon and Russ Wolfinger and Tin Nguyen and Mikhail Zaslavskiy and Jordi Abante and Abecassis, {Barbara Schmitz} and Nanne Aben and Delasa Aghamirzaie and Tero Aittokallio and Akhtari, {Farida S.} and Bissan Al-lazikani and Tanvir Alam and Amin Allam and Chad Allen and {de Almeida}, {Mariana Pelicano} and Doaa Altarawy and Vinicius Alves and Alicia Amadoz and Benedict Anchang and Antolin, {Albert A.} and Ash, {Jeremy R.} and Aznar, {Victoria Romeo} and Wail Ba-alawi and Moeen Bagheri and Vladimir Bajic and Gordon Ball and Ballester, {Pedro J.} and Delora Baptista and Christopher Bare and Mathilde Bateson and Andreas Bender and Denis Bertrand and Bhagya Wijayawardena and Boroevich, {Keith A.} and Evert Bosdriesz and Salim Bougouffa and Gergana Bounova and Thomas Brouwer and Barbara Bryant and Manuel Calaza and Alberto Calderone and Stefano Calza and Stephen Capuzzi and Jose Carbonell-Caballero and Daniel Carlin and Hannah Carter and Luisa Castagnoli and Remzi Celebi and Gianni Cesareni and Hyeokyoon Chang and Guocai Chen and Haoran Chen and Huiyuan Chen and Lijun Cheng and Ariel Chernomoretz and Davide Chicco and Kwang-Hyun Cho and Sunghwan Cho and Daeseon Choi and Jaejoon Choi and Kwanghun Choi and Minsoo Choi and Cock, {Martine De} and Elizabeth Coker and Isidro Cortes-Ciriano and Mikl{\'o}s Cserz{\"o} and Cankut Cubuk and Christina Curtis and Daele, {Dries Van} and Dang, {Cuong C.} and Tjeerd Dijkstra and Joaquin Dopazo and Sorin Draghici and Anastasios Drosou and Michel Dumontier and Friederike Ehrhart and Fatma-Elzahraa Eid and Mahmoud ElHefnawi and Haitham Elmarakeby and {van Engelen}, Bo and Engin, {Hatice Billur} and {de Esch}, Iwan and Chris Evelo and Falcao, {Andre O.} and Sherif Farag and Carlos Fernandez-Lozano and Kathleen Fisch and Asmund Flobak and Chiara Fornari and Foroushani, {Amir B. K.} and Fotso, {Donatien Chedom} and Denis Fourches and Stephen Friend and Arnoldo Frigessi and Feng Gao and Xiaoting Gao and Gerold, {Jeffrey M.} and Pierre Gestraud and Samik Ghosh and Jussi Gillberg and Antonia Godoy-Lorite and Lizzy Godynyuk and Adam Godzik and Anna Goldenberg and David Gomez-Cabrero and Mehmet Gonen and {de Graaf}, Chris and Harry Gray and Maxim Grechkin and Roger Guimera and Emre Guney and Benjamin Haibe-Kains and Younghyun Han and Takeshi Hase and Di He and Liye He and Heath, {Lenwood S.} and Hellton, {Kristoffer H.} and Manuela Helmer-Citterich and Hidalgo, {Marta R.} and Daniel Hidru and Hill, {Steven M.} and Sepp Hochreiter and Seungpyo Hong and Eivind Hovig and Ya-Chih Hsueh and Zhiyuan Hu and Huang, {Justin K.} and Huang, {R. Stephanie} and L{\'a}szl{\'o} Hunyady and Jinseub Hwang and Hwang, {Tae Hyun} and Woochang Hwang and Yongdeuk Hwang and Olexandr Isayev and {Don{\textquoteright}t Walk}, {Oliver Bear} and John Jack and Samad Jahandideh and Jiadong Ji and Yousang Jo and Kamola, {Piotr J.} and Kanev, {Georgi K.} and Loukia Karacosta and Mostafa Karimi and Samuel Kaski and Marat Kazanov and Khamis, {Abdullah M.} and Khan, {Suleiman Ali} and Kiani, {Narsis A.} and Allen Kim and Jinhan Kim and Juntae Kim and Kiseong Kim and Kyung Kim and Sunkyu Kim and Yongsoo Kim and Yunseong Kim and Kirk, {Paul D. W.} and Hiroaki Kitano and Gunter Klambauer and David Knowles and Melissa Ko and Alvaro Kohn-Luque and Kooistra, {Albert J.} and Kuenemann, {Melaine A.} and Martin Kuiper and Christoph Kurz and Mijin Kwon and {van Laarhoven}, Twan and Astrid Laegreid and Simone Lederer and Heewon Lee and Jeon Lee and Lee, {Yun Woo} and Eemeli Lepp_aho and Richard Lewis and Jing Li and Lang Li and James Liley and Lim, {Weng Khong} and Chieh Lin and Yiyi Liu and Yosvany Lopez and Joshua Low and Artem Lysenko and Daniel Machado and Neel Madhukar and Maeyer, {Dries De} and Malpartida, {Ana Belen} and Hiroshi Mamitsuka and Francesco Marabita and Kathleen Marchal and Pekka Marttinen and Daniel Mason and Alireza Mazaheri and Arfa Mehmood and Ali Mehreen and Magali Michaut and Miller, {Ryan A.} and Costas Mitsopoulos and Dezso Modos and Moerbeke, {Marijke Van} and Keagan Moo and Alison Motsinger-Reif and Rajiv Movva and Sebastian Muraru and Eugene Muratov and Mushthofa Mushthofa and Niranjan Nagarajan and Sigve Nakken and Aritro Nath and Pierre Neuvial and Richard Newton and Zheng Ning and Niz, {Carlos De} and Baldo Oliva and Catharina Olsen and Antonio Palmeri and Bhawan Panesar and Stavros Papadopoulos and Jaesub Park and Seonyeong Park and Sungjoon Park and Yudi Pawitan and Daniele Peluso and Sriram Pendyala and Jian Peng and Livia Perfetto and Stefano Pirro and Sylvia Plevritis and Regina Politi and Hoifung Poon and Eduard Porta and Isak Prellner and Kristina Preuer and Pujana, {Miguel Angel} and Ricardo Ramnarine and Reid, {John E.} and Fabien Reyal and Sylvia Richardson and Camir Ricketts and Linda Rieswijk and Miguel Rocha and Carmen Rodriguez-Gonzalvez and Kyle Roell and Daniel Rotroff and {de Ruiter}, {Julian R.} and Ploy Rukawa and Benjamin Sadacca and Zhaleh Safikhani and Fita Safitri and Marta Sales-Pardo and Sebastian Sauer and Moritz Schlichting and Seoane, {Jose A.} and Jordi Serra and Ming-Mei Shang and Alok Sharma and Hari Sharma and Yang Shen and Motoki Shiga and Moonshik Shin and Ziv Shkedy and Kevin Shopsowitz and Sam Sinai and Dylan Skola and Petr Smirnov and Soerensen, {Izel Fourie} and Peter Soerensen and Je-Hoon Song and Song, {Sang Ok} and Othman Soufan and Andreas Spitzmueller and Boris Steipe and Chayaporn Suphavilai and Tamayo, {Sergio Pulido} and David Tamborero and Jing Tang and Zia-ur-Rehman Tanoli and Marc Tarres-Deulofeu and Jesper Tegner and Liv Thommesen and Tonekaboni, {Seyed Ali Madani} and Hong Tran and Troyer, {Ewoud De} and Amy Truong and Tatsuhiko Tsunoda and G{\'a}bor Turu and Guang-Yo Tzeng and Lieven Verbeke and Santiago Videla and Consortium, {AstraZeneca-Sanger Drug Combination DREAM}",

year = "2019",

month = jun,

day = "17",

doi = "10.1038/s41467-019-09799-2",

language = "English",

volume = "10",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

number = "1",

}

Menden, MP, Wang, D, Mason, MJ, Szalai, B, Bulusu, KC, Guan, Y, Yu, T, Kang, J, Jeon, M, Wolfinger, R, Nguyen, T, Zaslavskiy, M, Abante, J, Abecassis, BS, Aben, N, Aghamirzaie, D, Aittokallio, T, Akhtari, FS, Al-lazikani, B, Alam, T, Allam, A, Allen, C, de Almeida, MP, Altarawy, D, Alves, V, Amadoz, A, Anchang, B, Antolin, AA, Ash, JR, Aznar, VR, Ba-alawi, W, Bagheri, M, Bajic, V, Ball, G, Ballester, PJ, Baptista, D, Bare, C, Bateson, M, Bender, A, Bertrand, D, Wijayawardena, B, Boroevich, KA, Bosdriesz, E, Bougouffa, S, Bounova, G, Brouwer, T, Bryant, B, Calaza, M, Calderone, A, Calza, S, Capuzzi, S, Carbonell-Caballero, J, Carlin, D, Carter, H, Castagnoli, L, Celebi, R, Cesareni, G, Chang, H, Chen, G, Chen, H, Chen, H, Cheng, L, Chernomoretz, A, Chicco, D, Cho, K-H, Cho, S, Choi, D, Choi, J, Choi, K, Choi, M, Cock, MD, Coker, E, Cortes-Ciriano, I, Cserzö, M, Cubuk, C, Curtis, C, Daele, DV, Dang, CC, Dijkstra, T, Dopazo, J, Draghici, S, Drosou, A, Dumontier, M, Ehrhart, F, Eid, F-E, ElHefnawi, M, Elmarakeby, H, van Engelen, B, Engin, HB, de Esch, I, Evelo, C, Falcao, AO, Farag, S, Fernandez-Lozano, C, Fisch, K, Flobak, A, Fornari, C, Foroushani, ABK, Fotso, DC, Fourches, D, Friend, S, Frigessi, A, Gao, F, Gao, X, Gerold, JM, Gestraud, P, Ghosh, S, Gillberg, J, Godoy-Lorite, A, Godynyuk, L, Godzik, A, Goldenberg, A, Gomez-Cabrero, D, Gonen, M, de Graaf, C, Gray, H, Grechkin, M, Guimera, R, Guney, E, Haibe-Kains, B, Han, Y, Hase, T, He, D, He, L, Heath, LS, Hellton, KH, Helmer-Citterich, M, Hidalgo, MR, Hidru, D, Hill, SM, Hochreiter, S, Hong, S, Hovig, E, Hsueh, Y-C, Hu, Z, Huang, JK, Huang, RS, Hunyady, L, Hwang, J, Hwang, TH, Hwang, W, Hwang, Y, Isayev, O, Don’t Walk, OB, Jack, J, Jahandideh, S, Ji, J, Jo, Y, Kamola, PJ, Kanev, GK, Karacosta, L, Karimi, M, Kaski, S, Kazanov, M, Khamis, AM, Khan, SA, Kiani, NA, Kim, A, Kim, J, Kim, J, Kim, K, Kim, K, Kim, S, Kim, Y, Kim, Y, Kirk, PDW, Kitano, H, Klambauer, G, Knowles, D, Ko, M, Kohn-Luque, A, Kooistra, AJ, Kuenemann, MA, Kuiper, M, Kurz, C, Kwon, M, van Laarhoven, T, Laegreid, A, Lederer, S, Lee, H, Lee, J, Lee, YW, Lepp_aho, E, Lewis, R, Li, J, Li, L, Liley, J, Lim, WK, Lin, C, Liu, Y, Lopez, Y, Low, J, Lysenko, A, Machado, D, Madhukar, N, Maeyer, DD, Malpartida, AB, Mamitsuka, H, Marabita, F, Marchal, K, Marttinen, P, Mason, D, Mazaheri, A, Mehmood, A, Mehreen, A, Michaut, M, Miller, RA, Mitsopoulos, C, Modos, D, Moerbeke, MV, Moo, K, Motsinger-Reif, A, Movva, R, Muraru, S, Muratov, E, Mushthofa, M, Nagarajan, N, Nakken, S, Nath, A, Neuvial, P, Newton, R, Ning, Z, Niz, CD, Oliva, B, Olsen, C, Palmeri, A, Panesar, B, Papadopoulos, S, Park, J, Park, S, Park, S, Pawitan, Y, Peluso, D, Pendyala, S, Peng, J, Perfetto, L, Pirro, S, Plevritis, S, Politi, R, Poon, H, Porta, E, Prellner, I, Preuer, K, Pujana, MA, Ramnarine, R, Reid, JE, Reyal, F, Richardson, S, Ricketts, C, Rieswijk, L, Rocha, M, Rodriguez-Gonzalvez, C, Roell, K, Rotroff, D, de Ruiter, JR, Rukawa, P, Sadacca, B, Safikhani, Z, Safitri, F, Sales-Pardo, M, Sauer, S, Schlichting, M, Seoane, JA, Serra, J, Shang, M-M, Sharma, A, Sharma, H, Shen, Y, Shiga, M, Shin, M, Shkedy, Z, Shopsowitz, K, Sinai, S, Skola, D, Smirnov, P, Soerensen, IF, Soerensen, P, Song, J-H, Song, SO, Soufan, O, Spitzmueller, A, Steipe, B, Suphavilai, C, Tamayo, SP, Tamborero, D, Tang, J , Tanoli, Z-R, Tarres-Deulofeu, M, Tegner, J, Thommesen, L, Tonekaboni, SAM, Tran, H, Troyer, ED, Truong, A, Tsunoda, T, Turu, G, Tzeng, G-Y, Verbeke, L, Videla, S & Consortium, A-SDCDREAM 2019, 'Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen', Nature Communications, vol. 10, no. 1, 2674. https://doi.org/10.1038/s41467-019-09799-2

TY - JOUR

T1 - Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

AU - Menden, Michael P.

AU - Wang, Dennis

AU - Mason, Mike J.

AU - Szalai, Bence

AU - Bulusu, Krishna C.

AU - Guan, Yuanfang

AU - Yu, Thomas

AU - Kang, Jaewoo

AU - Jeon, Minji

AU - Wolfinger, Russ

AU - Nguyen, Tin

AU - Zaslavskiy, Mikhail

AU - Abante, Jordi

AU - Abecassis, Barbara Schmitz

AU - Aben, Nanne

AU - Aghamirzaie, Delasa

AU - Aittokallio, Tero

AU - Akhtari, Farida S.

AU - Al-lazikani, Bissan

AU - Alam, Tanvir

AU - Allam, Amin

AU - Allen, Chad

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AU - Consortium, AstraZeneca-Sanger Drug Combination DREAM

PY - 2019/6/17

Y1 - 2019/6/17

KW - ANDROGEN RECEPTOR

KW - BREAST-CANCER

KW - CELL

KW - GENE

KW - INHIBITION

KW - LANDSCAPE

KW - MUTATIONS

KW - PATHWAY

KW - RESISTANCE

KW - RESOURCE

KW - 317 Pharmacy

KW - 3122 Cancers

U2 - 10.1038/s41467-019-09799-2

DO - 10.1038/s41467-019-09799-2

M3 - Article

SN - 2041-1723

VL - 10

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 2674

ER -