Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes

Jèssica Latorre, Francisco J. Ortega, Laura Liñares-Pose, José M. Moreno-Navarrete, Aina Lluch, Ferran Comas, Núria Oliveras-Cañellas, Wifredo Ricart, Marcus Höring, You Zhou, Gerhard Liebisch, P.A. Nidhina Haridas, Vesa M. Olkkonen, Miguel López, José M. Fernández-Real

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number102697
JournalEBioMedicine
Volume53
Number of pages16
ISSN2352-3964
DOIs
Publication statusPublished - Mar 2020
MoE publication typeA1 Journal article-refereed

Fields of Science

  • 3111 Biomedicine
  • MicroRNAs
  • AMPK
  • Hepatocytes
  • Fatty acid homeostasis
  • Steatosis
  • METFORMIN
  • NAFLD
  • CHOLESTEROL
  • DE-NOVO LIPOGENESIS
  • FATTY LIVER-DISEASE
  • TRANSCRIPTION
  • ATHEROSCLEROSIS
  • METABOLISM
  • HIGH-THROUGHPUT QUANTIFICATION
  • MOLECULAR-MECHANISMS

Cite this

Latorre, J., Ortega, F. J., Liñares-Pose, L., Moreno-Navarrete, J. M., Lluch, A., Comas, F., ... Fernández-Real, J. M. (2020). Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes. EBioMedicine, 53, [102697]. https://doi.org/10.1016/j.ebiom.2020.102697