Comprehensive transcriptomic analysis shows disturbed calcium homeostasis and deregulation of T lymphocyte apoptosis in inclusion body myositis

Mridul Johari; Anna Vihola; Johanna Palmio; Manu Jokela; Per Harald Jonson; Jaakko Sarparanta; Sanna Huovinen; Marco Savarese; Peter Hackman; Bjarne Udd

doi:10.1007/s00415-022-11029-7

Comprehensive transcriptomic analysis shows disturbed calcium homeostasis and deregulation of T lymphocyte apoptosis in inclusion body myositis

Mridul Johari, Anna Vihola, Johanna Palmio, Manu Jokela, Per Harald Jonson, Jaakko Sarparanta, Sanna Huovinen, Marco Savarese, Peter Hackman, Bjarne Udd

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Journal of Neurology
Volume	269
Pages (from-to)	4161–4173
Number of pages	13
ISSN	0340-5354
DOIs	https://doi.org/10.1007/s00415-022-11029-7
Publication status	Published - Aug 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

Inclusion body myositis
Calcium
Differential expression
Differential splicing
T cells
NEGATIVE SELECTION
CELL
EXPRESSION
NUR77
ASSOCIATION
ACTIVATION
LCK
3112 Neurosciences
3124 Neurology and psychiatry

Access to Document

10.1007/s00415-022-11029-7

s00415-022-11029-7Final published version, 3.35 MBLicence: CC BY

Cite this

@article{52758c63e13a4ba19ada9bb5fdfa536a,

title = "Comprehensive transcriptomic analysis shows disturbed calcium homeostasis and deregulation of T lymphocyte apoptosis in inclusion body myositis",

keywords = "Inclusion body myositis, Calcium, Differential expression, Differential splicing, T cells, NEGATIVE SELECTION, CELL, EXPRESSION, NUR77, ASSOCIATION, ACTIVATION, LCK, 3112 Neurosciences, 3124 Neurology and psychiatry",

author = "Mridul Johari and Anna Vihola and Johanna Palmio and Manu Jokela and Jonson, {Per Harald} and Jaakko Sarparanta and Sanna Huovinen and Marco Savarese and Peter Hackman and Bjarne Udd",

year = "2022",

month = aug,

doi = "10.1007/s00415-022-11029-7",

language = "English",

volume = "269",

pages = "4161–4173",

journal = "Journal of Neurology",

issn = "0340-5354",

publisher = "Springer Heidelberg",

}

TY - JOUR

T1 - Comprehensive transcriptomic analysis shows disturbed calcium homeostasis and deregulation of T lymphocyte apoptosis in inclusion body myositis

AU - Johari, Mridul

AU - Vihola, Anna

AU - Palmio, Johanna

AU - Jokela, Manu

AU - Jonson, Per Harald

AU - Sarparanta, Jaakko

AU - Huovinen, Sanna

AU - Savarese, Marco

AU - Hackman, Peter

AU - Udd, Bjarne

PY - 2022/8

Y1 - 2022/8

KW - Inclusion body myositis

KW - Calcium

KW - Differential expression

KW - Differential splicing

KW - T cells

KW - NEGATIVE SELECTION

KW - CELL

KW - EXPRESSION

KW - NUR77

KW - ASSOCIATION

KW - ACTIVATION

KW - LCK

KW - 3112 Neurosciences

KW - 3124 Neurology and psychiatry

U2 - 10.1007/s00415-022-11029-7

DO - 10.1007/s00415-022-11029-7

M3 - Article

VL - 269

SP - 4161

EP - 4173

JO - Journal of Neurology

JF - Journal of Neurology

SN - 0340-5354

ER -