Compressive stress-mediated p38 activation required for ER alpha plus phenotype in breast cancer

Pauliina M. Munne; Lahja Martikainen; Iiris Räty; Kia Bertula; null Nonappa; Janika Ruuska; Hanna Ala-Hongisto; Aino Peura; Babette Hollmann; Lilya Euro; Kerim Yavuz; Linda Patrikainen; Maria Salmela; Juho Pokki; Mikko Kivento; Juho Väänänen; Tomi Suomi; Liina Nevalaita; Minna Mutka; Panu Kovanen; Marjut Leidenius; Tuomo Meretoja; Katja Hukkinen; Outi Monni; Jeroen Pouwels; Biswajyoti Sahu; Johanna Mattson; Heikki Joensuu; Päivi Heikkilä; Laura L. Elo; Ciara Metcalfe; Melissa R. Junttila; Olli Ikkala; Juha Klefström

doi:10.1038/s41467-021-27220-9

Compressive stress-mediated p38 activation required for ER alpha plus phenotype in breast cancer

Pauliina M. Munne, Lahja Martikainen, Iiris Räty, Kia Bertula, Nonappa, Janika Ruuska, Hanna Ala-Hongisto, Aino Peura, Babette Hollmann, Lilya Euro, Kerim Yavuz, Linda Patrikainen, Maria Salmela, Juho Pokki, Mikko Kivento, Juho Väänänen, Tomi Suomi, Liina Nevalaita, Minna Mutka, Panu KovanenMarjut Leidenius, Tuomo Meretoja, Katja Hukkinen, Outi Monni, Jeroen Pouwels, Biswajyoti Sahu, Johanna Mattson, Heikki Joensuu, Päivi Heikkilä, Laura L. Elo, Ciara Metcalfe, Melissa R. Junttila, Olli Ikkala, Juha Klefström

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	6967
Journal	Nature Communications
Volume	12
Issue number	1
Number of pages	17
ISSN	2041-1723
DOIs	https://doi.org/10.1038/s41467-021-27220-9
Publication status	Published - 29 Nov 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

GROWTH-FACTOR
MAMMOGRAPHIC DENSITY
ESTROGEN-RECEPTOR
STEM-CELLS
EXPRESSION
EZH2
RISK
DIFFERENTIATION
CLASSIFICATION
TRANSCRIPTION
3122 Cancers

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10.1038/s41467-021-27220-9

s41467-021-27220-9Final published version, 29.5 MBLicence: CC BY

Cite this

Munne, P. M., Martikainen, L., Räty, I., Bertula, K., Nonappa, Ruuska, J., Ala-Hongisto, H., Peura, A., Hollmann, B., Euro, L., Yavuz, K., Patrikainen, L., Salmela, M., Pokki, J., Kivento, M., Väänänen, J., Suomi, T., Nevalaita, L., Mutka, M., ... Klefström, J. (2021). Compressive stress-mediated p38 activation required for ER alpha plus phenotype in breast cancer. Nature Communications, 12(1), Article 6967. https://doi.org/10.1038/s41467-021-27220-9

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title = "Compressive stress-mediated p38 activation required for ER alpha plus phenotype in breast cancer",

keywords = "GROWTH-FACTOR, MAMMOGRAPHIC DENSITY, ESTROGEN-RECEPTOR, STEM-CELLS, EXPRESSION, EZH2, RISK, DIFFERENTIATION, CLASSIFICATION, TRANSCRIPTION, 3122 Cancers",

author = "Munne, {Pauliina M.} and Lahja Martikainen and Iiris R{\"a}ty and Kia Bertula and Nonappa and Janika Ruuska and Hanna Ala-Hongisto and Aino Peura and Babette Hollmann and Lilya Euro and Kerim Yavuz and Linda Patrikainen and Maria Salmela and Juho Pokki and Mikko Kivento and Juho V{\"a}{\"a}n{\"a}nen and Tomi Suomi and Liina Nevalaita and Minna Mutka and Panu Kovanen and Marjut Leidenius and Tuomo Meretoja and Katja Hukkinen and Outi Monni and Jeroen Pouwels and Biswajyoti Sahu and Johanna Mattson and Heikki Joensuu and P{\"a}ivi Heikkil{\"a} and Elo, {Laura L.} and Ciara Metcalfe and Junttila, {Melissa R.} and Olli Ikkala and Juha Klefstr{\"o}m",

year = "2021",

month = nov,

day = "29",

doi = "10.1038/s41467-021-27220-9",

language = "English",

volume = "12",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

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Munne, PM, Martikainen, L, Räty, I, Bertula, K, Nonappa, Ruuska, J, Ala-Hongisto, H, Peura, A, Hollmann, B, Euro, L, Yavuz, K, Patrikainen, L, Salmela, M, Pokki, J, Kivento, M, Väänänen, J, Suomi, T, Nevalaita, L, Mutka, M , Kovanen, P , Leidenius, M , Meretoja, T , Hukkinen, K , Monni, O , Pouwels, J , Sahu, B , Mattson, J , Joensuu, H , Heikkilä, P, Elo, LL, Metcalfe, C, Junttila, MR, Ikkala, O & Klefström, J 2021, 'Compressive stress-mediated p38 activation required for ER alpha plus phenotype in breast cancer', Nature Communications, vol. 12, no. 1, 6967. https://doi.org/10.1038/s41467-021-27220-9

TY - JOUR

T1 - Compressive stress-mediated p38 activation required for ER alpha plus phenotype in breast cancer

AU - Munne, Pauliina M.

AU - Martikainen, Lahja

AU - Räty, Iiris

AU - Bertula, Kia

AU - Nonappa, null

AU - Ruuska, Janika

AU - Ala-Hongisto, Hanna

AU - Peura, Aino

AU - Hollmann, Babette

AU - Euro, Lilya

AU - Yavuz, Kerim

AU - Patrikainen, Linda

AU - Salmela, Maria

AU - Pokki, Juho

AU - Kivento, Mikko

AU - Väänänen, Juho

AU - Suomi, Tomi

AU - Nevalaita, Liina

AU - Mutka, Minna

AU - Kovanen, Panu

AU - Leidenius, Marjut

AU - Meretoja, Tuomo

AU - Hukkinen, Katja

AU - Monni, Outi

AU - Pouwels, Jeroen

AU - Sahu, Biswajyoti

AU - Mattson, Johanna

AU - Joensuu, Heikki

AU - Heikkilä, Päivi

AU - Elo, Laura L.

AU - Metcalfe, Ciara

AU - Junttila, Melissa R.

AU - Ikkala, Olli

AU - Klefström, Juha

PY - 2021/11/29

Y1 - 2021/11/29

KW - GROWTH-FACTOR

KW - MAMMOGRAPHIC DENSITY

KW - ESTROGEN-RECEPTOR

KW - STEM-CELLS

KW - EXPRESSION

KW - EZH2

KW - RISK

KW - DIFFERENTIATION

KW - CLASSIFICATION

KW - TRANSCRIPTION

KW - 3122 Cancers

U2 - 10.1038/s41467-021-27220-9

DO - 10.1038/s41467-021-27220-9

M3 - Article

SN - 2041-1723

VL - 12

JO - Nature Communications

JF - Nature Communications

IS - 1

M1 - 6967

ER -