Coordination sphere of the third metal site is essential to the activity and metal selectivity of alkaline phosphatases

Dimitris Koutsioulis; Andrzej Lyskowski; Seija Mäki; Ellen Guthrie; Georges Feller; Vassilis Bouriotis; Pirkko Heikinheimo

doi:10.1002/pro.284

Coordination sphere of the third metal site is essential to the activity and metal selectivity of alkaline phosphatases

Dimitris Koutsioulis, Andrzej Lyskowski, Seija Mäki, Ellen Guthrie, Georges Feller, Vassilis Bouriotis, Pirkko Heikinheimo

Institute of Biotechnology

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Protein Science
Volume	19
Issue number	1
Pages (from-to)	75-84
Number of pages	10
ISSN	0961-8368
DOIs	https://doi.org/10.1002/pro.284
Publication status	Published - 2010
MoE publication type	A1 Journal article-refereed

Fields of Science

crystal structure
enzyme mechanism
extremophile
metal catalysis
psychrophile
ANGSTROM CRYSTAL-STRUCTURE
PYROPHOSPHATASE
SPECIFICITY
ENZYME
TAB5
ION
MUTATIONS
MECHANISM
EVOLUTION
CATALYSIS
118 Biological sciences

Access to Document

10.1002/pro.284

Cite this

@article{73ddd2682fd94b49afc10fa719604da1,

title = "Coordination sphere of the third metal site is essential to the activity and metal selectivity of alkaline phosphatases",

keywords = "crystal structure, enzyme mechanism, extremophile, metal catalysis, psychrophile, ANGSTROM CRYSTAL-STRUCTURE, PYROPHOSPHATASE, SPECIFICITY, ENZYME, TAB5, ION, MUTATIONS, MECHANISM, EVOLUTION, CATALYSIS, 118 Biological sciences",

author = "Dimitris Koutsioulis and Andrzej Lyskowski and Seija M{\"a}ki and Ellen Guthrie and Georges Feller and Vassilis Bouriotis and Pirkko Heikinheimo",

year = "2010",

doi = "10.1002/pro.284",

language = "English",

volume = "19",

pages = "75--84",

journal = "Protein Science",

issn = "0961-8368",

publisher = "Wiley Blackwell",

number = "1",

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TY - JOUR

T1 - Coordination sphere of the third metal site is essential to the activity and metal selectivity of alkaline phosphatases

AU - Koutsioulis, Dimitris

AU - Lyskowski, Andrzej

AU - Mäki, Seija

AU - Guthrie, Ellen

AU - Feller, Georges

AU - Bouriotis, Vassilis

AU - Heikinheimo, Pirkko

PY - 2010

Y1 - 2010

KW - crystal structure

KW - enzyme mechanism

KW - extremophile

KW - metal catalysis

KW - psychrophile

KW - ANGSTROM CRYSTAL-STRUCTURE

KW - PYROPHOSPHATASE

KW - SPECIFICITY

KW - ENZYME

KW - TAB5

KW - ION

KW - MUTATIONS

KW - MECHANISM

KW - EVOLUTION

KW - CATALYSIS

KW - 118 Biological sciences

U2 - 10.1002/pro.284

DO - 10.1002/pro.284

M3 - Article

SN - 0961-8368

VL - 19

SP - 75

EP - 84

JO - Protein Science

JF - Protein Science

IS - 1

ER -