Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake

Chang-Fang Wang, Ermei M. Mäkilä, Martti H. Kaasalainen, Dongfei Liu, Mirkka P. Sarparanta, Anu J. Airaksinen, Jarno J. Salonen, Jouni T. Hirvonen, Hélder A. Santos

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalBiomaterials
Volume35
Issue number4
Pages (from-to)1257-1266
Number of pages10
ISSN0142-9612
DOIs
Publication statusPublished - Jan 2014
MoE publication typeA1 Journal article-refereed

Fields of Science

  • Porous silicon nanoparticle
  • Copper-free click chemistry
  • Surface modification
  • Drug delivery
  • Intracellular uptake
  • Cancer therapy
  • ACUTE MYELOID-LEUKEMIA
  • MESOPOROUS SILICON
  • SURFACE-CHEMISTRY
  • IN-VITRO
  • CELLULAR-ASSOCIATION
  • CLICK CHEMISTRY
  • DELIVERY
  • SORAFENIB
  • CANCER
  • BIODISTRIBUTION
  • 317 Pharmacy

Cite this

@article{94fe190b49be4600b9effe3a82bd0b09,
title = "Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake",
keywords = "Porous silicon nanoparticle, Copper-free click chemistry, Surface modification, Drug delivery, Intracellular uptake, Cancer therapy, ACUTE MYELOID-LEUKEMIA, MESOPOROUS SILICON, SURFACE-CHEMISTRY, IN-VITRO, CELLULAR-ASSOCIATION, CLICK CHEMISTRY, DELIVERY, SORAFENIB, CANCER, BIODISTRIBUTION, 317 Pharmacy",
author = "Chang-Fang Wang and M{\"a}kil{\"a}, {Ermei M.} and Kaasalainen, {Martti H.} and Dongfei Liu and Sarparanta, {Mirkka P.} and Airaksinen, {Anu J.} and Salonen, {Jarno J.} and Hirvonen, {Jouni T.} and Santos, {H{\'e}lder A.}",
year = "2014",
month = "1",
doi = "10.1016/j.biomaterials.2013.10.065",
language = "English",
volume = "35",
pages = "1257--1266",
journal = "Biomaterials",
issn = "0142-9612",
publisher = "ELSEVIER SCI IRELAND LTD",
number = "4",

}

Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake. / Wang, Chang-Fang; Mäkilä, Ermei M.; Kaasalainen, Martti H.; Liu, Dongfei; Sarparanta, Mirkka P.; Airaksinen, Anu J.; Salonen, Jarno J.; Hirvonen, Jouni T.; Santos, Hélder A.

In: Biomaterials, Vol. 35, No. 4, 01.2014, p. 1257-1266.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake

AU - Wang, Chang-Fang

AU - Mäkilä, Ermei M.

AU - Kaasalainen, Martti H.

AU - Liu, Dongfei

AU - Sarparanta, Mirkka P.

AU - Airaksinen, Anu J.

AU - Salonen, Jarno J.

AU - Hirvonen, Jouni T.

AU - Santos, Hélder A.

PY - 2014/1

Y1 - 2014/1

KW - Porous silicon nanoparticle

KW - Copper-free click chemistry

KW - Surface modification

KW - Drug delivery

KW - Intracellular uptake

KW - Cancer therapy

KW - ACUTE MYELOID-LEUKEMIA

KW - MESOPOROUS SILICON

KW - SURFACE-CHEMISTRY

KW - IN-VITRO

KW - CELLULAR-ASSOCIATION

KW - CLICK CHEMISTRY

KW - DELIVERY

KW - SORAFENIB

KW - CANCER

KW - BIODISTRIBUTION

KW - 317 Pharmacy

U2 - 10.1016/j.biomaterials.2013.10.065

DO - 10.1016/j.biomaterials.2013.10.065

M3 - Article

VL - 35

SP - 1257

EP - 1266

JO - Biomaterials

JF - Biomaterials

SN - 0142-9612

IS - 4

ER -