Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span

M. Grunewald; S. Kumar; H. Sharife; E. Volinsky; A. Gileles-Hillel; T. Licht; A. Permyakova; L. Hinden; S. Azar; Y. Friedmann; P. Kupetz; R. Tzuberi; A. Anisimov; K. Alitalo; M. Horwitz; S. Leebhoff; O. Z. Khoma; R. Hlushchuk; Valentin G Djonov; R. Abramovitch; J. Tam; E. Keshet

doi:10.1126/science.abc8479

Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span

M. Grunewald, S. Kumar, H. Sharife, E. Volinsky, A. Gileles-Hillel, T. Licht, A. Permyakova, L. Hinden, S. Azar, Y. Friedmann, P. Kupetz, R. Tzuberi, A. Anisimov, K. Alitalo, M. Horwitz, S. Leebhoff, O. Z. Khoma, R. Hlushchuk, Valentin G Djonov, R. AbramovitchJ. Tam, E. Keshet

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Science
Volume	373
Issue number	6554
Pages (from-to)	533-+
Number of pages	56
ISSN	0036-8075
DOIs	https://doi.org/10.1126/science.abc8479
Publication status	Published - 30 Jul 2021
MoE publication type	A1 Journal article-refereed

Fields of Science

ENDOTHELIAL GROWTH-FACTOR
LONGEVITY
NEOVASCULARIZATION
MECHANISMS
INSIGHTS
PROVIDES
SYSTEM
MUSCLE
LIVER
3121 General medicine, internal medicine and other clinical medicine

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10.1126/science.abc8479

Grynewald_Science_2021Accepted author manuscript, 4.68 MB

Cite this

Grunewald, M., Kumar, S., Sharife, H., Volinsky, E., Gileles-Hillel, A., Licht, T., Permyakova, A., Hinden, L., Azar, S., Friedmann, Y., Kupetz, P., Tzuberi, R., Anisimov, A., Alitalo, K., Horwitz, M., Leebhoff, S., Khoma, O. Z., Hlushchuk, R., Djonov, V. G., ... Keshet, E. (2021). Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span. Science, 373(6554), 533-+. https://doi.org/10.1126/science.abc8479

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author = "M. Grunewald and S. Kumar and H. Sharife and E. Volinsky and A. Gileles-Hillel and T. Licht and A. Permyakova and L. Hinden and S. Azar and Y. Friedmann and P. Kupetz and R. Tzuberi and A. Anisimov and K. Alitalo and M. Horwitz and S. Leebhoff and Khoma, {O. Z.} and R. Hlushchuk and Djonov, {Valentin G} and R. Abramovitch and J. Tam and E. Keshet",

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Grunewald, M, Kumar, S, Sharife, H, Volinsky, E, Gileles-Hillel, A, Licht, T, Permyakova, A, Hinden, L, Azar, S, Friedmann, Y, Kupetz, P, Tzuberi, R, Anisimov, A , Alitalo, K, Horwitz, M, Leebhoff, S, Khoma, OZ, Hlushchuk, R, Djonov, VG, Abramovitch, R, Tam, J & Keshet, E 2021, 'Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span', Science, vol. 373, no. 6554, pp. 533-+. https://doi.org/10.1126/science.abc8479

TY - JOUR

T1 - Counteracting age-related VEGF signaling insufficiency promotes healthy aging and extends life span

AU - Grunewald, M.

AU - Kumar, S.

AU - Sharife, H.

AU - Volinsky, E.

AU - Gileles-Hillel, A.

AU - Licht, T.

AU - Permyakova, A.

AU - Hinden, L.

AU - Azar, S.

AU - Friedmann, Y.

AU - Kupetz, P.

AU - Tzuberi, R.

AU - Anisimov, A.

AU - Alitalo, K.

AU - Horwitz, M.

AU - Leebhoff, S.

AU - Khoma, O. Z.

AU - Hlushchuk, R.

AU - Djonov, Valentin G

AU - Abramovitch, R.

AU - Tam, J.

AU - Keshet, E.

PY - 2021/7/30

Y1 - 2021/7/30

KW - ENDOTHELIAL GROWTH-FACTOR

KW - LONGEVITY

KW - NEOVASCULARIZATION

KW - MECHANISMS

KW - INSIGHTS

KW - PROVIDES

KW - SYSTEM

KW - MUSCLE

KW - LIVER

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1126/science.abc8479

DO - 10.1126/science.abc8479

M3 - Article

VL - 373

SP - 533-+

JO - Science

JF - Science

SN - 0036-8075

IS - 6554

ER -