CRISPR correction of the Finnish ornithine delta-aminotransferase mutation restores metabolic homeostasis in iPSC from patients with gyrate atrophy

Rocio Maldonado; Sami Jalil; Timo Keskinen; Anni I. Nieminen; Mervi E. Hyvönen; Risto Lapatto; Kirmo Wartiovaara

doi:10.1016/j.ymgmr.2022.100863

CRISPR correction of the Finnish ornithine delta-aminotransferase mutation restores metabolic homeostasis in iPSC from patients with gyrate atrophy

Rocio Maldonado, Sami Jalil, Timo Keskinen, Anni I. Nieminen, Mervi E. Hyvönen, Risto Lapatto, Kirmo Wartiovaara

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	100863
Journal	Molecular Genetics and Metabolism Reports
Volume	31
Number of pages	6
ISSN	2214-4269
DOIs	https://doi.org/10.1016/j.ymgmr.2022.100863
Publication status	Published - Jun 2022
MoE publication type	A1 Journal article-refereed

Fields of Science

3111 Biomedicine
Cas9
Crispr
Hoga oat
Gene editing
Gyrate atrophy

Access to Document

10.1016/j.ymgmr.2022.100863

1-s2.0-S2214426922000234-mainFinal published version, 1.45 MBLicence: CC BY

FIMM Metabolomics (LS-RIA/ Metabo-HiLIFE)
Nieminen, A. I. (Manager)
Institute for Molecular Medicine Finland
Facility/equipment: Core Facility

Cite this

@article{6124a416156044ad8a0a37bc7ef30498,

title = "CRISPR correction of the Finnish ornithine delta-aminotransferase mutation restores metabolic homeostasis in iPSC from patients with gyrate atrophy",

keywords = "3111 Biomedicine, Cas9, Crispr, Hoga oat, Gene editing, Gyrate atrophy",

author = "Rocio Maldonado and Sami Jalil and Timo Keskinen and Nieminen, {Anni I.} and Hyv{\"o}nen, {Mervi E.} and Risto Lapatto and Kirmo Wartiovaara",

year = "2022",

month = jun,

doi = "10.1016/j.ymgmr.2022.100863",

language = "English",

volume = "31",

journal = "Molecular Genetics and Metabolism Reports",

issn = "2214-4269",

publisher = "Elsevier Scientific Publ. Co",

}

TY - JOUR

T1 - CRISPR correction of the Finnish ornithine delta-aminotransferase mutation restores metabolic homeostasis in iPSC from patients with gyrate atrophy

AU - Maldonado, Rocio

AU - Jalil, Sami

AU - Keskinen, Timo

AU - Nieminen, Anni I.

AU - Hyvönen, Mervi E.

AU - Lapatto, Risto

AU - Wartiovaara, Kirmo

PY - 2022/6

Y1 - 2022/6

KW - 3111 Biomedicine

KW - Cas9

KW - Crispr

KW - Hoga oat

KW - Gene editing

KW - Gyrate atrophy

U2 - 10.1016/j.ymgmr.2022.100863

DO - 10.1016/j.ymgmr.2022.100863

M3 - Article

SN - 2214-4269

VL - 31

JO - Molecular Genetics and Metabolism Reports

JF - Molecular Genetics and Metabolism Reports

M1 - 100863

ER -

CRISPR correction of the Finnish ornithine delta-aminotransferase mutation restores metabolic homeostasis in iPSC from patients with gyrate atrophy

Fields of Science

Access to Document

Equipment

FIMM Metabolomics (LS-RIA/ Metabo-HiLIFE)

Cite this