Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8

Helinä Kahma, Anne M. Filppula, Terhi Launiainen, Jenni Viinamäki, Mikko Neuvonen, Eric A. Evangelista, Rheem A. Totah, Janne T. Backman

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalDrug Metabolism and Disposition
Volume47
Issue number4
Pages (from-to)436-443
Number of pages8
ISSN0090-9556
DOIs
Publication statusPublished - 1 Apr 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • HUMAN LIVER-MICROSOMES
  • INCREASES PLASMA-CONCENTRATIONS
  • CYTOCHROME-P450 ENZYMES
  • MARKEDLY INCREASES
  • MASS-SPECTROMETRY
  • GEMFIBROZIL
  • GLUCURONIDATION
  • INHIBITION
  • CLOPIDOGREL
  • METABOLISM
  • 317 Pharmacy
  • 3111 Biomedicine

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