Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Solveig K. Sieberts; Fan Zhu; Javier Garcia-Garcia; Eli Stahl; Abhishek Pratap; Gaurav Pandey; Dimitrios Pappas; Daniel Aguilar; Bernat Anton; Jaume Bonet; Ridvan Eksi; Oriol Fornes; Emre Guney; Hongdong Li; Manuel Alejandro Marin; Bharat Panwar; Joan Planas-Iglesias; Daniel Poglayen; Jing Cui; Andre O. Falcao; Christine Suver; Bruce Hoff; Venkat S. K. Balagurusamy; Donna Dillenberger; Elias Chaibub Neto; Thea Norman; Tero Aittokallio; Muhammad Ammad-ud-din; Chloe-Agathe Azencott; Victor Bellon; Valentina Boeva; Kerstin Bunte; Himanshu Chheda; Lu Cheng; Jukka Corander; Michel Dumontier; Anna Goldenberg; Peddinti Gopalacharyulu; Mohsen Hajiloo; Daniel Hidru; Alok Jaiswal; Samuel Kaski; Beyrem Khalfaoui; Suleiman Ali Khan; Eric R. Kramer; Pekka Marttinen; Matti Pirinen; Janna Saarela; Jing Tang; Krister Wennerberg; Rheumatoid Arth Challenge

doi:10.1038/ncomms12460

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Solveig K. Sieberts, Fan Zhu, Javier Garcia-Garcia, Eli Stahl, Abhishek Pratap, Gaurav Pandey, Dimitrios Pappas, Daniel Aguilar, Bernat Anton, Jaume Bonet, Ridvan Eksi, Oriol Fornes, Emre Guney, Hongdong Li, Manuel Alejandro Marin, Bharat Panwar, Joan Planas-Iglesias, Daniel Poglayen, Jing Cui, Andre O. FalcaoChristine Suver, Bruce Hoff, Venkat S. K. Balagurusamy, Donna Dillenberger, Elias Chaibub Neto, Thea Norman, Tero Aittokallio, Muhammad Ammad-ud-din, Chloe-Agathe Azencott, Victor Bellon, Valentina Boeva, Kerstin Bunte, Himanshu Chheda, Lu Cheng, Jukka Corander, Michel Dumontier, Anna Goldenberg, Peddinti Gopalacharyulu, Mohsen Hajiloo, Daniel Hidru, Alok Jaiswal, Samuel Kaski, Beyrem Khalfaoui, Suleiman Ali Khan, Eric R. Kramer, Pekka Marttinen, Matti Pirinen, Janna Saarela, Jing Tang, Krister Wennerberg, Rheumatoid Arth Challenge

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Article number	12460
Journal	Nature Communications
Volume	7
Number of pages	9
ISSN	2041-1723
DOIs	https://doi.org/10.1038/ncomms12460
Publication status	Published - Aug 2016
MoE publication type	A1 Journal article-refereed

Bibliographical note

Correction: vol 7, 13205, 2016, doi:10.1038/ncomms13205

Fields of Science

GENOME-WIDE ASSOCIATION
STACKED GENERALIZATION
MISSING HERITABILITY
NETWORK INFERENCE
CLINICAL-RESPONSE
COMPLEX TRAITS
DISEASE
RISK
METAANALYSIS
INFLIXIMAB
3121 General medicine, internal medicine and other clinical medicine
113 Computer and information sciences

Access to Document

10.1038/ncomms12460

ncomms12460Final published version, 361 KBLicence: CC BY

Cite this

Sieberts, S. K., Zhu, F., Garcia-Garcia, J., Stahl, E., Pratap, A., Pandey, G., Pappas, D., Aguilar, D., Anton, B., Bonet, J., Eksi, R., Fornes, O., Guney, E., Li, H., Marin, M. A., Panwar, B., Planas-Iglesias, J., Poglayen, D., Cui, J., ... Rheumatoid Arth Challenge (2016). Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nature Communications, 7, Article 12460. https://doi.org/10.1038/ncomms12460

@article{5d2c20e4b28b4520b0459dbc72021b31,

title = "Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis",

keywords = "GENOME-WIDE ASSOCIATION, STACKED GENERALIZATION, MISSING HERITABILITY, NETWORK INFERENCE, CLINICAL-RESPONSE, COMPLEX TRAITS, DISEASE, RISK, METAANALYSIS, INFLIXIMAB, 3121 General medicine, internal medicine and other clinical medicine, 113 Computer and information sciences",

author = "Sieberts, {Solveig K.} and Fan Zhu and Javier Garcia-Garcia and Eli Stahl and Abhishek Pratap and Gaurav Pandey and Dimitrios Pappas and Daniel Aguilar and Bernat Anton and Jaume Bonet and Ridvan Eksi and Oriol Fornes and Emre Guney and Hongdong Li and Marin, {Manuel Alejandro} and Bharat Panwar and Joan Planas-Iglesias and Daniel Poglayen and Jing Cui and Falcao, {Andre O.} and Christine Suver and Bruce Hoff and Balagurusamy, {Venkat S. K.} and Donna Dillenberger and Neto, {Elias Chaibub} and Thea Norman and Tero Aittokallio and Muhammad Ammad-ud-din and Chloe-Agathe Azencott and Victor Bellon and Valentina Boeva and Kerstin Bunte and Himanshu Chheda and Lu Cheng and Jukka Corander and Michel Dumontier and Anna Goldenberg and Peddinti Gopalacharyulu and Mohsen Hajiloo and Daniel Hidru and Alok Jaiswal and Samuel Kaski and Beyrem Khalfaoui and Khan, {Suleiman Ali} and Kramer, {Eric R.} and Pekka Marttinen and Matti Pirinen and Janna Saarela and Jing Tang and Krister Wennerberg and {Rheumatoid Arth Challenge}",

note = "Correction: vol 7, 13205, 2016, doi:10.1038/ncomms13205 ",

year = "2016",

month = aug,

doi = "10.1038/ncomms12460",

language = "English",

volume = "7",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "Nature Publishing Group",

}

Sieberts, SK, Zhu, F, Garcia-Garcia, J, Stahl, E, Pratap, A, Pandey, G, Pappas, D, Aguilar, D, Anton, B, Bonet, J, Eksi, R, Fornes, O, Guney, E, Li, H, Marin, MA, Panwar, B, Planas-Iglesias, J, Poglayen, D, Cui, J, Falcao, AO, Suver, C, Hoff, B, Balagurusamy, VSK, Dillenberger, D, Neto, EC, Norman, T, Aittokallio, T, Ammad-ud-din, M, Azencott, C-A, Bellon, V, Boeva, V, Bunte, K, Chheda, H, Cheng, L, Corander, J, Dumontier, M, Goldenberg, A, Gopalacharyulu, P, Hajiloo, M, Hidru, D, Jaiswal, A, Kaski, S, Khalfaoui, B, Khan, SA, Kramer, ER, Marttinen, P, Pirinen, M , Saarela, J , Tang, J, Wennerberg, K & Rheumatoid Arth Challenge 2016, 'Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis', Nature Communications, vol. 7, 12460. https://doi.org/10.1038/ncomms12460

TY - JOUR

T1 - Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

AU - Sieberts, Solveig K.

AU - Zhu, Fan

AU - Garcia-Garcia, Javier

AU - Stahl, Eli

AU - Pratap, Abhishek

AU - Pandey, Gaurav

AU - Pappas, Dimitrios

AU - Aguilar, Daniel

AU - Anton, Bernat

AU - Bonet, Jaume

AU - Eksi, Ridvan

AU - Fornes, Oriol

AU - Guney, Emre

AU - Li, Hongdong

AU - Marin, Manuel Alejandro

AU - Panwar, Bharat

AU - Planas-Iglesias, Joan

AU - Poglayen, Daniel

AU - Cui, Jing

AU - Falcao, Andre O.

AU - Suver, Christine

AU - Hoff, Bruce

AU - Balagurusamy, Venkat S. K.

AU - Dillenberger, Donna

AU - Neto, Elias Chaibub

AU - Norman, Thea

AU - Aittokallio, Tero

AU - Ammad-ud-din, Muhammad

AU - Azencott, Chloe-Agathe

AU - Bellon, Victor

AU - Boeva, Valentina

AU - Bunte, Kerstin

AU - Chheda, Himanshu

AU - Cheng, Lu

AU - Corander, Jukka

AU - Dumontier, Michel

AU - Goldenberg, Anna

AU - Gopalacharyulu, Peddinti

AU - Hajiloo, Mohsen

AU - Hidru, Daniel

AU - Jaiswal, Alok

AU - Kaski, Samuel

AU - Khalfaoui, Beyrem

AU - Khan, Suleiman Ali

AU - Kramer, Eric R.

AU - Marttinen, Pekka

AU - Pirinen, Matti

AU - Saarela, Janna

AU - Tang, Jing

AU - Wennerberg, Krister

AU - Rheumatoid Arth Challenge

N1 - Correction: vol 7, 13205, 2016, doi:10.1038/ncomms13205

PY - 2016/8

Y1 - 2016/8

KW - GENOME-WIDE ASSOCIATION

KW - STACKED GENERALIZATION

KW - MISSING HERITABILITY

KW - NETWORK INFERENCE

KW - CLINICAL-RESPONSE

KW - COMPLEX TRAITS

KW - DISEASE

KW - RISK

KW - METAANALYSIS

KW - INFLIXIMAB

KW - 3121 General medicine, internal medicine and other clinical medicine

KW - 113 Computer and information sciences

U2 - 10.1038/ncomms12460

DO - 10.1038/ncomms12460

M3 - Article

SN - 2041-1723

VL - 7

JO - Nature Communications

JF - Nature Communications

M1 - 12460

ER -