Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

Solveig K. Sieberts, Fan Zhu, Javier Garcia-Garcia, Eli Stahl, Abhishek Pratap, Gaurav Pandey, Dimitrios Pappas, Daniel Aguilar, Bernat Anton, Jaume Bonet, Ridvan Eksi, Oriol Fornes, Emre Guney, Hongdong Li, Manuel Alejandro Marin, Bharat Panwar, Joan Planas-Iglesias, Daniel Poglayen, Jing Cui, Andre O. FalcaoChristine Suver, Bruce Hoff, Venkat S. K. Balagurusamy, Donna Dillenberger, Elias Chaibub Neto, Thea Norman, Tero Aittokallio, Muhammad Ammad-ud-din, Chloe-Agathe Azencott, Victor Bellon, Valentina Boeva, Kerstin Bunte, Himanshu Chheda, Lu Cheng, Jukka Corander, Michel Dumontier, Anna Goldenberg, Peddinti Gopalacharyulu, Mohsen Hajiloo, Daniel Hidru, Alok Jaiswal, Samuel Kaski, Beyrem Khalfaoui, Suleiman Ali Khan, Eric R. Kramer, Pekka Marttinen, Matti Pirinen, Janna Saarela, Jing Tang, Krister Wennerberg, Rheumatoid Arth Challenge

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article number12460
JournalNature Communications
Volume7
Number of pages9
ISSN2041-1723
DOIs
Publication statusPublished - Aug 2016
MoE publication typeA1 Journal article-refereed

Fields of Science

  • GENOME-WIDE ASSOCIATION
  • STACKED GENERALIZATION
  • MISSING HERITABILITY
  • NETWORK INFERENCE
  • CLINICAL-RESPONSE
  • COMPLEX TRAITS
  • DISEASE
  • RISK
  • METAANALYSIS
  • INFLIXIMAB
  • 3121 Internal medicine
  • 113 Computer and information sciences

Cite this

Sieberts, S. K., Zhu, F., Garcia-Garcia, J., Stahl, E., Pratap, A., Pandey, G., ... Rheumatoid Arth Challenge (2016). Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. Nature Communications, 7, [12460]. https://doi.org/10.1038/ncomms12460
Sieberts, Solveig K. ; Zhu, Fan ; Garcia-Garcia, Javier ; Stahl, Eli ; Pratap, Abhishek ; Pandey, Gaurav ; Pappas, Dimitrios ; Aguilar, Daniel ; Anton, Bernat ; Bonet, Jaume ; Eksi, Ridvan ; Fornes, Oriol ; Guney, Emre ; Li, Hongdong ; Marin, Manuel Alejandro ; Panwar, Bharat ; Planas-Iglesias, Joan ; Poglayen, Daniel ; Cui, Jing ; Falcao, Andre O. ; Suver, Christine ; Hoff, Bruce ; Balagurusamy, Venkat S. K. ; Dillenberger, Donna ; Neto, Elias Chaibub ; Norman, Thea ; Aittokallio, Tero ; Ammad-ud-din, Muhammad ; Azencott, Chloe-Agathe ; Bellon, Victor ; Boeva, Valentina ; Bunte, Kerstin ; Chheda, Himanshu ; Cheng, Lu ; Corander, Jukka ; Dumontier, Michel ; Goldenberg, Anna ; Gopalacharyulu, Peddinti ; Hajiloo, Mohsen ; Hidru, Daniel ; Jaiswal, Alok ; Kaski, Samuel ; Khalfaoui, Beyrem ; Khan, Suleiman Ali ; Kramer, Eric R. ; Marttinen, Pekka ; Pirinen, Matti ; Saarela, Janna ; Tang, Jing ; Wennerberg, Krister ; Rheumatoid Arth Challenge. / Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. In: Nature Communications. 2016 ; Vol. 7.
@article{5d2c20e4b28b4520b0459dbc72021b31,
title = "Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis",
keywords = "GENOME-WIDE ASSOCIATION, STACKED GENERALIZATION, MISSING HERITABILITY, NETWORK INFERENCE, CLINICAL-RESPONSE, COMPLEX TRAITS, DISEASE, RISK, METAANALYSIS, INFLIXIMAB, 3121 Internal medicine, 113 Computer and information sciences",
author = "Sieberts, {Solveig K.} and Fan Zhu and Javier Garcia-Garcia and Eli Stahl and Abhishek Pratap and Gaurav Pandey and Dimitrios Pappas and Daniel Aguilar and Bernat Anton and Jaume Bonet and Ridvan Eksi and Oriol Fornes and Emre Guney and Hongdong Li and Marin, {Manuel Alejandro} and Bharat Panwar and Joan Planas-Iglesias and Daniel Poglayen and Jing Cui and Falcao, {Andre O.} and Christine Suver and Bruce Hoff and Balagurusamy, {Venkat S. K.} and Donna Dillenberger and Neto, {Elias Chaibub} and Thea Norman and Tero Aittokallio and Muhammad Ammad-ud-din and Chloe-Agathe Azencott and Victor Bellon and Valentina Boeva and Kerstin Bunte and Himanshu Chheda and Lu Cheng and Jukka Corander and Michel Dumontier and Anna Goldenberg and Peddinti Gopalacharyulu and Mohsen Hajiloo and Daniel Hidru and Alok Jaiswal and Samuel Kaski and Beyrem Khalfaoui and Khan, {Suleiman Ali} and Kramer, {Eric R.} and Pekka Marttinen and Matti Pirinen and Janna Saarela and Jing Tang and Krister Wennerberg and {Rheumatoid Arth Challenge}",
note = "Correction: vol 7, 13205, 2016, doi:10.1038/ncomms13205 Volume: Proceeding volume:",
year = "2016",
month = "8",
doi = "10.1038/ncomms12460",
language = "English",
volume = "7",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "Nature Publishing Group",

}

Sieberts, SK, Zhu, F, Garcia-Garcia, J, Stahl, E, Pratap, A, Pandey, G, Pappas, D, Aguilar, D, Anton, B, Bonet, J, Eksi, R, Fornes, O, Guney, E, Li, H, Marin, MA, Panwar, B, Planas-Iglesias, J, Poglayen, D, Cui, J, Falcao, AO, Suver, C, Hoff, B, Balagurusamy, VSK, Dillenberger, D, Neto, EC, Norman, T, Aittokallio, T, Ammad-ud-din, M, Azencott, C-A, Bellon, V, Boeva, V, Bunte, K, Chheda, H, Cheng, L, Corander, J, Dumontier, M, Goldenberg, A, Gopalacharyulu, P, Hajiloo, M, Hidru, D, Jaiswal, A, Kaski, S, Khalfaoui, B, Khan, SA, Kramer, ER, Marttinen, P, Pirinen, M, Saarela, J, Tang, J, Wennerberg, K & Rheumatoid Arth Challenge 2016, 'Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis', Nature Communications, vol. 7, 12460. https://doi.org/10.1038/ncomms12460

Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis. / Sieberts, Solveig K.; Zhu, Fan; Garcia-Garcia, Javier; Stahl, Eli; Pratap, Abhishek; Pandey, Gaurav; Pappas, Dimitrios; Aguilar, Daniel; Anton, Bernat; Bonet, Jaume; Eksi, Ridvan; Fornes, Oriol; Guney, Emre; Li, Hongdong; Marin, Manuel Alejandro; Panwar, Bharat; Planas-Iglesias, Joan; Poglayen, Daniel; Cui, Jing; Falcao, Andre O.; Suver, Christine; Hoff, Bruce; Balagurusamy, Venkat S. K.; Dillenberger, Donna; Neto, Elias Chaibub; Norman, Thea; Aittokallio, Tero; Ammad-ud-din, Muhammad; Azencott, Chloe-Agathe; Bellon, Victor; Boeva, Valentina; Bunte, Kerstin; Chheda, Himanshu; Cheng, Lu; Corander, Jukka; Dumontier, Michel; Goldenberg, Anna; Gopalacharyulu, Peddinti; Hajiloo, Mohsen; Hidru, Daniel; Jaiswal, Alok; Kaski, Samuel; Khalfaoui, Beyrem; Khan, Suleiman Ali; Kramer, Eric R.; Marttinen, Pekka; Pirinen, Matti; Saarela, Janna; Tang, Jing; Wennerberg, Krister; Rheumatoid Arth Challenge.

In: Nature Communications, Vol. 7, 12460, 08.2016.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Crowdsourced assessment of common genetic contribution to predicting anti-TNF treatment response in rheumatoid arthritis

AU - Sieberts, Solveig K.

AU - Zhu, Fan

AU - Garcia-Garcia, Javier

AU - Stahl, Eli

AU - Pratap, Abhishek

AU - Pandey, Gaurav

AU - Pappas, Dimitrios

AU - Aguilar, Daniel

AU - Anton, Bernat

AU - Bonet, Jaume

AU - Eksi, Ridvan

AU - Fornes, Oriol

AU - Guney, Emre

AU - Li, Hongdong

AU - Marin, Manuel Alejandro

AU - Panwar, Bharat

AU - Planas-Iglesias, Joan

AU - Poglayen, Daniel

AU - Cui, Jing

AU - Falcao, Andre O.

AU - Suver, Christine

AU - Hoff, Bruce

AU - Balagurusamy, Venkat S. K.

AU - Dillenberger, Donna

AU - Neto, Elias Chaibub

AU - Norman, Thea

AU - Aittokallio, Tero

AU - Ammad-ud-din, Muhammad

AU - Azencott, Chloe-Agathe

AU - Bellon, Victor

AU - Boeva, Valentina

AU - Bunte, Kerstin

AU - Chheda, Himanshu

AU - Cheng, Lu

AU - Corander, Jukka

AU - Dumontier, Michel

AU - Goldenberg, Anna

AU - Gopalacharyulu, Peddinti

AU - Hajiloo, Mohsen

AU - Hidru, Daniel

AU - Jaiswal, Alok

AU - Kaski, Samuel

AU - Khalfaoui, Beyrem

AU - Khan, Suleiman Ali

AU - Kramer, Eric R.

AU - Marttinen, Pekka

AU - Pirinen, Matti

AU - Saarela, Janna

AU - Tang, Jing

AU - Wennerberg, Krister

AU - Rheumatoid Arth Challenge

N1 - Correction: vol 7, 13205, 2016, doi:10.1038/ncomms13205 Volume: Proceeding volume:

PY - 2016/8

Y1 - 2016/8

KW - GENOME-WIDE ASSOCIATION

KW - STACKED GENERALIZATION

KW - MISSING HERITABILITY

KW - NETWORK INFERENCE

KW - CLINICAL-RESPONSE

KW - COMPLEX TRAITS

KW - DISEASE

KW - RISK

KW - METAANALYSIS

KW - INFLIXIMAB

KW - 3121 Internal medicine

KW - 113 Computer and information sciences

U2 - 10.1038/ncomms12460

DO - 10.1038/ncomms12460

M3 - Article

VL - 7

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

M1 - 12460

ER -