CYP2D6 Polymorphisms and the Safety and Gametocytocidal Activity of Single-Dose Primaquine for Plasmodium falciparum

Helmi Pett, John Bradley, Joseph Okebe, Alassane Dicko, Alfred B. Tiono, Bronner P. Goncalves, Will Stone, Ingrid Chen, Kjerstin Lanke, Mikko Neuvonen, Anna-Liina Mustaniemi, Alice C. Eziefula, Roly Gosling, Umberto D'Alessandro, Chris Drakeley, Mikko Niemi, Teun Bousema

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
Article numberARTN e00538-19
JournalAntimicrobial Agents and Chemotherapy
Volume63
Issue number10
Number of pages9
ISSN0066-4804
DOIs
Publication statusPublished - Oct 2019
MoE publication typeA1 Journal article-refereed

Fields of Science

  • cytochrome P450
  • drug metabolism
  • elimination
  • gametocyte
  • genetic polymorphisms
  • malaria
  • metabolite
  • primaquine
  • safety
  • transmission
  • ARTEMETHER-LUMEFANTRINE
  • CYTOCHROME-P450 2D6
  • DOUBLE-BLIND
  • MALARIA
  • TRANSMISSION
  • CHILDREN
  • UPDATE
  • VIVAX
  • 3111 Biomedicine
  • 1183 Plant biology, microbiology, virology
  • 317 Pharmacy

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