Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner

Anna Kreutzman, Beatriz Colom-Fernandez, Ana Marcos Jimenez, Mette Ilander, Carlos Cuesta-Mateos, Yaiza Perez-Garcia, Cristina Delgado Arevalo, Oscar Bruck, Henna Hakanen, Jani Saarela, Alvaro Ortega-Carrion, Ana de Rosendo, Alba Juanes-Garcia, Juan Luis Steegmann, Satu Mustjoki, Miguel Vicente-Manzanares, Cecilia Munoz-Calleja

Research output: Contribution to journalArticleScientificpeer-review

Original languageEnglish
JournalClinical Cancer Research
Volume23
Issue number21
Pages (from-to)6697-6707
Number of pages11
ISSN1078-0432
DOIs
Publication statusPublished - 1 Nov 2017
MoE publication typeA1 Journal article-refereed

Fields of Science

  • CHRONIC MYELOID-LEUKEMIA
  • DIAGNOSED CHRONIC-PHASE
  • CHROMOSOME-POSITIVE LEUKEMIAS
  • PLEURAL EFFUSION
  • CELL-ADHESION
  • FOLLOW-UP
  • NK-CELLS
  • IMATINIB
  • THERAPY
  • KINASE
  • 3122 Cancers

Cite this

Kreutzman, Anna ; Colom-Fernandez, Beatriz ; Marcos Jimenez, Ana ; Ilander, Mette ; Cuesta-Mateos, Carlos ; Perez-Garcia, Yaiza ; Delgado Arevalo, Cristina ; Bruck, Oscar ; Hakanen, Henna ; Saarela, Jani ; Ortega-Carrion, Alvaro ; de Rosendo, Ana ; Juanes-Garcia, Alba ; Luis Steegmann, Juan ; Mustjoki, Satu ; Vicente-Manzanares, Miguel ; Munoz-Calleja, Cecilia. / Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner. In: Clinical Cancer Research. 2017 ; Vol. 23, No. 21. pp. 6697-6707.
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title = "Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner",
keywords = "CHRONIC MYELOID-LEUKEMIA, DIAGNOSED CHRONIC-PHASE, CHROMOSOME-POSITIVE LEUKEMIAS, PLEURAL EFFUSION, CELL-ADHESION, FOLLOW-UP, NK-CELLS, IMATINIB, THERAPY, KINASE, 3122 Cancers",
author = "Anna Kreutzman and Beatriz Colom-Fernandez and {Marcos Jimenez}, Ana and Mette Ilander and Carlos Cuesta-Mateos and Yaiza Perez-Garcia and {Delgado Arevalo}, Cristina and Oscar Bruck and Henna Hakanen and Jani Saarela and Alvaro Ortega-Carrion and {de Rosendo}, Ana and Alba Juanes-Garcia and {Luis Steegmann}, Juan and Satu Mustjoki and Miguel Vicente-Manzanares and Cecilia Munoz-Calleja",
year = "2017",
month = "11",
day = "1",
doi = "10.1158/1078-0432.CCR-16-0667",
language = "English",
volume = "23",
pages = "6697--6707",
journal = "Clinical Cancer Research",
issn = "1078-0432",
publisher = "American Association for Cancer Research",
number = "21",

}

Kreutzman, A, Colom-Fernandez, B, Marcos Jimenez, A, Ilander, M, Cuesta-Mateos, C, Perez-Garcia, Y, Delgado Arevalo, C, Bruck, O, Hakanen, H, Saarela, J, Ortega-Carrion, A, de Rosendo, A, Juanes-Garcia, A, Luis Steegmann, J, Mustjoki, S, Vicente-Manzanares, M & Munoz-Calleja, C 2017, 'Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner', Clinical Cancer Research, vol. 23, no. 21, pp. 6697-6707. https://doi.org/10.1158/1078-0432.CCR-16-0667

Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner. / Kreutzman, Anna; Colom-Fernandez, Beatriz; Marcos Jimenez, Ana; Ilander, Mette; Cuesta-Mateos, Carlos; Perez-Garcia, Yaiza; Delgado Arevalo, Cristina; Bruck, Oscar; Hakanen, Henna; Saarela, Jani; Ortega-Carrion, Alvaro; de Rosendo, Ana; Juanes-Garcia, Alba; Luis Steegmann, Juan; Mustjoki, Satu; Vicente-Manzanares, Miguel; Munoz-Calleja, Cecilia.

In: Clinical Cancer Research, Vol. 23, No. 21, 01.11.2017, p. 6697-6707.

Research output: Contribution to journalArticleScientificpeer-review

TY - JOUR

T1 - Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner

AU - Kreutzman, Anna

AU - Colom-Fernandez, Beatriz

AU - Marcos Jimenez, Ana

AU - Ilander, Mette

AU - Cuesta-Mateos, Carlos

AU - Perez-Garcia, Yaiza

AU - Delgado Arevalo, Cristina

AU - Bruck, Oscar

AU - Hakanen, Henna

AU - Saarela, Jani

AU - Ortega-Carrion, Alvaro

AU - de Rosendo, Ana

AU - Juanes-Garcia, Alba

AU - Luis Steegmann, Juan

AU - Mustjoki, Satu

AU - Vicente-Manzanares, Miguel

AU - Munoz-Calleja, Cecilia

PY - 2017/11/1

Y1 - 2017/11/1

KW - CHRONIC MYELOID-LEUKEMIA

KW - DIAGNOSED CHRONIC-PHASE

KW - CHROMOSOME-POSITIVE LEUKEMIAS

KW - PLEURAL EFFUSION

KW - CELL-ADHESION

KW - FOLLOW-UP

KW - NK-CELLS

KW - IMATINIB

KW - THERAPY

KW - KINASE

KW - 3122 Cancers

U2 - 10.1158/1078-0432.CCR-16-0667

DO - 10.1158/1078-0432.CCR-16-0667

M3 - Article

VL - 23

SP - 6697

EP - 6707

JO - Clinical Cancer Research

JF - Clinical Cancer Research

SN - 1078-0432

IS - 21

ER -