Deletion of TOP3 beta, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

Georg Stoll; Olli Pietiläinen; Bastian Linder; Jaana Suvisaari; Cornelia Brosi; William Hennah; Virpi Maria Leppä; Minna Torniainen; Samuli Ripatti; Sirpa Ala-Mello; Oliver Plottner; Karola Rehnstrom; Annamari Tuulio-Henriksson; Teppo Varilo; Jonna Tallila; Kati Kristiansson; Matti Isohanni; Jaakko Kaprio; Johan G. Eriksson; Olli T. Raitakari; Terho Lehtimaki; Marjo-Riitta Jarvelin; Veikko Salomaa; Matthew Hurles; Hreinn Stefansson; Leena Palotie; Patrick F. Sullivan; Tiina Paunio; Jouko Lönnqvist; Mark J. Daly; Utz Fischer; Nelson B. Freimer; Aarno Palotie

doi:10.1038/nn.3484

Deletion of TOP3 beta, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

Georg Stoll, Olli Pietiläinen, Bastian Linder, Jaana Suvisaari, Cornelia Brosi, William Hennah, Virpi Maria Leppä, Minna Torniainen, Samuli Ripatti, Sirpa Ala-Mello, Oliver Plottner, Karola Rehnstrom, Annamari Tuulio-Henriksson, Teppo Varilo, Jonna Tallila, Kati Kristiansson, Matti Isohanni, Jaakko Kaprio, Johan G. Eriksson, Olli T. RaitakariTerho Lehtimaki, Marjo-Riitta Jarvelin, Veikko Salomaa, Matthew Hurles, Hreinn Stefansson, Leena Palotie, Patrick F. Sullivan, Tiina Paunio, Jouko Lönnqvist, Mark J. Daly, Utz Fischer, Nelson B. Freimer, Aarno Palotie

Research output: Contribution to journal › Article › Scientific › peer-review

Original language	English
Journal	Nature Neuroscience
Volume	16
Issue number	9
Pages (from-to)	1228-U99
Number of pages	13
ISSN	1097-6256
DOIs	https://doi.org/10.1038/nn.3484
Publication status	Published - Sept 2013
MoE publication type	A1 Journal article-refereed

Fields of Science

FRAGILE-X-SYNDROME
MENTAL-RETARDATION PROTEIN
GENOME-WIDE ASSOCIATION
HIDDEN-MARKOV MODEL
SNP GENOTYPING DATA
VELOCARDIOFACIAL SYNDROME
FOUNDER POPULATION
DIGEORGE-SYNDROME
SCHIZOPHRENIA
RNA
3112 Neurosciences

Access to Document

10.1038/nn.3484

RNA analysis in Finnish Schizophrenia Families
Hennah, W. (Creator), National Institute for Health and Welfare, 18 Jun 2013
http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE48072
Dataset

FIMM Genomics (LS-RIA/ HGI)
Donner, K. M. (Manager)
Institute for Molecular Medicine Finland
Facility/equipment: Core Facility

Cite this

Stoll, G., Pietiläinen, O., Linder, B., Suvisaari, J., Brosi, C., Hennah, W., Leppä, V. M., Torniainen, M., Ripatti, S., Ala-Mello, S., Plottner, O., Rehnstrom, K., Tuulio-Henriksson, A., Varilo, T., Tallila, J., Kristiansson, K., Isohanni, M., Kaprio, J., Eriksson, J. G., ... Palotie, A. (2013). Deletion of TOP3 beta, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders. Nature Neuroscience, 16(9), 1228-U99. https://doi.org/10.1038/nn.3484

@article{ab024f16dfc0490f8758c7af73fcaae9,

title = "Deletion of TOP3 beta, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders",

keywords = "FRAGILE-X-SYNDROME, MENTAL-RETARDATION PROTEIN, GENOME-WIDE ASSOCIATION, HIDDEN-MARKOV MODEL, SNP GENOTYPING DATA, VELOCARDIOFACIAL SYNDROME, FOUNDER POPULATION, DIGEORGE-SYNDROME, SCHIZOPHRENIA, RNA, 3112 Neurosciences",

author = "Georg Stoll and Olli Pietil{\"a}inen and Bastian Linder and Jaana Suvisaari and Cornelia Brosi and William Hennah and Lepp{\"a}, \{Virpi Maria\} and Minna Torniainen and Samuli Ripatti and Sirpa Ala-Mello and Oliver Plottner and Karola Rehnstrom and Annamari Tuulio-Henriksson and Teppo Varilo and Jonna Tallila and Kati Kristiansson and Matti Isohanni and Jaakko Kaprio and Eriksson, \{Johan G.\} and Raitakari, \{Olli T.\} and Terho Lehtimaki and Marjo-Riitta Jarvelin and Veikko Salomaa and Matthew Hurles and Hreinn Stefansson and Leena Palotie and Sullivan, \{Patrick F.\} and Tiina Paunio and Jouko L{\"o}nnqvist and Daly, \{Mark J.\} and Utz Fischer and Freimer, \{Nelson B.\} and Aarno Palotie",

year = "2013",

month = sep,

doi = "10.1038/nn.3484",

language = "English",

volume = "16",

pages = "1228--U99",

journal = "Nature Neuroscience",

issn = "1097-6256",

publisher = "Nature Research ",

number = "9",

}

Stoll, G, Pietiläinen, O, Linder, B, Suvisaari, J, Brosi, C, Hennah, W, Leppä, VM, Torniainen, M, Ripatti, S , Ala-Mello, S, Plottner, O, Rehnstrom, K, Tuulio-Henriksson, A , Varilo, T, Tallila, J, Kristiansson, K, Isohanni, M, Kaprio, J , Eriksson, JG, Raitakari, OT, Lehtimaki, T, Jarvelin, M-R, Salomaa, V, Hurles, M, Stefansson, H, Palotie, L, Sullivan, PF, Paunio, T , Lönnqvist, J, Daly, MJ, Fischer, U, Freimer, NB & Palotie, A 2013, 'Deletion of TOP3 beta, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders', Nature Neuroscience, vol. 16, no. 9, pp. 1228-U99. https://doi.org/10.1038/nn.3484

TY - JOUR

T1 - Deletion of TOP3 beta, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

AU - Stoll, Georg

AU - Pietiläinen, Olli

AU - Linder, Bastian

AU - Suvisaari, Jaana

AU - Brosi, Cornelia

AU - Hennah, William

AU - Leppä, Virpi Maria

AU - Torniainen, Minna

AU - Ripatti, Samuli

AU - Ala-Mello, Sirpa

AU - Plottner, Oliver

AU - Rehnstrom, Karola

AU - Tuulio-Henriksson, Annamari

AU - Varilo, Teppo

AU - Tallila, Jonna

AU - Kristiansson, Kati

AU - Isohanni, Matti

AU - Kaprio, Jaakko

AU - Eriksson, Johan G.

AU - Raitakari, Olli T.

AU - Lehtimaki, Terho

AU - Jarvelin, Marjo-Riitta

AU - Salomaa, Veikko

AU - Hurles, Matthew

AU - Stefansson, Hreinn

AU - Palotie, Leena

AU - Sullivan, Patrick F.

AU - Paunio, Tiina

AU - Lönnqvist, Jouko

AU - Daly, Mark J.

AU - Fischer, Utz

AU - Freimer, Nelson B.

AU - Palotie, Aarno

PY - 2013/9

Y1 - 2013/9

KW - FRAGILE-X-SYNDROME

KW - MENTAL-RETARDATION PROTEIN

KW - GENOME-WIDE ASSOCIATION

KW - HIDDEN-MARKOV MODEL

KW - SNP GENOTYPING DATA

KW - VELOCARDIOFACIAL SYNDROME

KW - FOUNDER POPULATION

KW - DIGEORGE-SYNDROME

KW - SCHIZOPHRENIA

KW - RNA

KW - 3112 Neurosciences

U2 - 10.1038/nn.3484

DO - 10.1038/nn.3484

M3 - Article

SN - 1097-6256

VL - 16

SP - 1228-U99

JO - Nature Neuroscience

JF - Nature Neuroscience

IS - 9

ER -

Deletion of TOP3 beta, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disorders

Fields of Science

Access to Document

Datasets

RNA analysis in Finnish Schizophrenia Families

Equipment

FIMM Genomics (LS-RIA/ HGI)

Cite this